DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG4629 and grp

DIOPT Version :9

Sequence 1:	NP_608564.3	Gene:	CG4629 / 33284	FlyBaseID:	FBgn0031299	Length:	570	Species:	Drosophila melanogaster
Sequence 2:	NP_477011.1	Gene:	grp / 34993	FlyBaseID:	FBgn0261278	Length:	512	Species:	Drosophila melanogaster

Alignment Length:	495	Identity:	121/495 - (24%)
Similarity:	215/495 - (43%)	Gaps:	94/495 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly    72 IGRGNFSKVKLAVHQLTRDKVAIKVVDLDRAGLDAKALRMLSSEIATLECVHHPNILRLFEVVET 136
            :|.|.:.:|||.:::.|.:.||:|:|||.:....|.::|   .|:...:.:...:|||.|. ..:
  Fly    28 LGEGAYGEVKLLINRQTGEAVAMKMVDLKKHPDAANSVR---KEVCIQKMLQDKHILRFFG-KRS 88

  Fly   137 LGRV-YLVTEWIRGGELYNHITQGGPLREIHAAPLLKQLLLAVKHMHSLGYVHRDIKAENVLLLS 200
            .|.| |:..|:..||||::.|.....:.:..|.....|||..:.::|..|..|||:|.||:||..
  Fly    89 QGSVEYIFLEYAAGGELFDRIEPDVGMPQHEAQRYFTQLLSGLNYLHQRGIAHRDLKPENLLLDE 153

  Fly   201 EDRLKLADFGFSTQL-INGANQKLDTFCGSPPYAAPELFSDDHYIGAPVDVWALGILLYFMVVGN 264
            .|.:|::|||.:|.. ..|..:.||..||:.||.|||:. ...|...|.|:|:.|::|..|:.|.
  Fly   154 HDNVKISDFGMATMFRCKGKERLLDKRCGTLPYVAPEVL-QKAYHAQPADLWSCGVILVTMLAGE 217

  Fly   265 MPFRAPTIPGLKAAILK-GDYLLPGQLSLP-------CIRLIQRILIHIPAQRPTIDDMLNSQFV 321
            :|:..|:....:....: .|:   .||..|       .|.|::::|...|..|.|::..|:.::.
  Fly   218 LPWDQPSTNCTEFTNWRDNDH---WQLQTPWSKLDTLAISLLRKLLATSPGTRLTLEKTLDHKWC 279

  Fly   322 TCPKLSADLMQWEINQHTKPVKRS-----IFWVRSKSHRLRKSASLRDRYAEVVKKPAIS--MNT 379
            .        ||:..|:.:..:..|     |...::|..||:.||.|.:...:.:.:...|  |.|
  Fly   280 N--------MQFADNERSYDLVDSAAALEICSPKAKRQRLQSSAHLSNGLDDSISRNYCSQPMPT 336

  Fly   380 RQQDEMF---------------VQNFLQPIEMGHELLVP-------VSSQLKEPQSTEQ------ 416
            .:.|:.|               .|...|...:.:....|       :::|:.:.|:..|
  Fly   337 MRSDDDFNVRLGSGRSKEDGGDRQTLAQEARLSYSFSQPALLDDLLLATQMNQTQNASQNYFQRL 401

  Fly   417 AKRPTRRYMFCGSLKKKVTPMETEPEKQLANGGQSIGSAKINPWNVEVAEDCPLFKNYDAETGSC 481
            .:|.||.:         ||....:..|:|....:.:|                   .|..:.|..
  Fly   402 VRRMTRFF---------VTTRWDDTIKRLVGTIERLG-------------------GYTCKFGDD 438

  Fly   482 VMLPTNTEDLSQLGALEFEARQILAELGLTSEMLINARQS 521
            .::..:|.|.::| .|.|:|..|    .:..::|::.|.|
  Fly   439 GVVTVSTVDRNKL-RLVFKAHII----EMDGKILVDCRLS 473

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4629	NP_608564.3	STKc_NIM1	63..321	CDD:270977	79/258 (31%)
CG4629	NP_608564.3	S_TKc	66..321	CDD:214567	79/258 (31%)
grp	NP_477011.1	STKc_Chk1	20..279	CDD:270971	79/258 (31%)
grp	NP_477011.1	S_TKc	22..278	CDD:214567	79/257 (31%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24343
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	2.010