DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG4629 and ssp2

DIOPT Version :9

Sequence 1:	NP_608564.3	Gene:	CG4629 / 33284	FlyBaseID:	FBgn0031299	Length:	570	Species:	Drosophila melanogaster
Sequence 2:	NP_588376.1	Gene:	ssp2 / 2539109	PomBaseID:	SPCC74.03c	Length:	576	Species:	Schizosaccharomyces pombe

Alignment Length:	458	Identity:	130/458 - (28%)
Similarity:	212/458 - (46%)	Gaps:	77/458 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly    61 RRIGLYRFCGDIGRGNFSKVKLAVHQLTRDKVAIKVVDLDRAGLDAKALRM-LSSEIATLECVHH 124
            |.||.|.....:|.|:|.|||||.|..|:.|||:|.:  .|..|....:.| :..||:.|:.:.|
pombe    29 RHIGPYIIRETLGEGSFGKVKLATHYKTQQKVALKFI--SRQLLKKSDMHMRVEREISYLKLLRH 91

  Fly   125 PNILRLFEVVETLGRVYLVTEWIRGGELYNHITQGGPLREIHAAPLLKQLLLAVKHMHSLGYVHR 189
            |:|::|::|:.|...:.:|.|: .||||:::|.:...:.|.......:|::.|:::.|....|||
pombe    92 PHIIKLYDVITTPTDIVMVIEY-AGGELFDYIVEKKRMTEDEGRRFFQQIICAIEYCHRHKIVHR 155

  Fly   190 DIKAENVLLLSEDRLKLADFGFSTQLINGANQKLDTFCGSPPYAAPELFSDDHYIGAPVDVWALG 254
            |:|.||:||.....:|:||||.|..:.:|  ..|.|.||||.|||||:.:...|.|..||||:.|
pombe   156 DLKPENLLLDDNLNVKIADFGLSNIMTDG--NFLKTSCGSPNYAAPEVINGKLYAGPEVDVWSCG 218

  Fly   255 ILLYFMVVGNMPFRAPTIPGLKAAILKGDYLLPGQLSLPCIRLIQRILIHIPAQRPTIDDMLNSQ 319
            |:||.|:||.:||....||.|...:....|::|..||.....||:|:::..|.||.||.::...
pombe   219 IVLYVMLVGRLPFDDEFIPNLFKKVNSCVYVMPDFLSPGAQSLIRRMIVADPMQRITIQEIRRD- 282

  Fly   320 FVTCPKLSADLMQWEINQHTKPVKRSIFWVRSKSHRLRKSASLRDRYAE--VVKKPAISMNTRQQ 382
                |..:.:|..:                      ||....::..||:  :|.|...:|..
pombe   283 ----PWFNVNLPDY----------------------LRPMEEVQGSYADSRIVSKLGEAMGF--- 318

  Fly   383 DEMFVQNFLQPIEMGHEL-----LVPVSSQLKEPQSTEQAKR--------PTRRYMFCGSLKKK- 433
            .|.::...|:..| .:|:     |:..:..::|.....::||        |.....:...|:||
pombe   319 SEDYIVEALRSDE-NNEVKEAYNLLHENQVIQEKSHLSKSKRVDSFLSVSPPAFSEYTSELQKKS 382

  Fly   434 ----VTPMETEPEKQLANGGQSIGSAKINPWNVEVAEDCPLFKNYDAETGSCVMLPTNTEDLSQL 494
                :.|....|.                 |.|   .|.|.:.....::..||::||..::..::
pombe   383 KQELIDPTLEGPR-----------------WTV---SDPPTYAKQTIDSNICVLVPTAEKNKLEM 427

  Fly   495 GAL 497
            ..|
pombe   428 RTL 430

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4629	NP_608564.3	STKc_NIM1	63..321	CDD:270977	97/258 (38%)
CG4629	NP_608564.3	S_TKc	66..321	CDD:214567	95/255 (37%)
ssp2	NP_588376.1	STKc_AMPK_alpha	31..285	CDD:270981	98/263 (37%)
		S_TKc	34..285	CDD:214567	96/260 (37%)
		UBA_SNF1_fungi	305..351	CDD:270519	8/49 (16%)
		AdenylateSensor	451..573	CDD:293187
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910