Protein Alignment CG4629 and aak-2

DIOPT Version :10

• Sequence 1: NP_608564.3
• Gene: CG4629 / 33284
• FlyBaseID: FBgn0031299
• Length: 570
• Species: Drosophila melanogaster
• Sequence 2: NP_510710.2
• Gene: aak-2 / 181727
• WormBaseID: WBGene00020142
• Length: 626
• Species: Caenorhabditis elegans
• Alignment Length: 524
• Identity: 134/524 - (25%)
• Similarity: 239/524 - (45%)
• Gaps: 74/524 - (14%)

  Fly    62 RIGLYRFCGDIGRGNFSKVKLAVHQLTRDKVAIKVVDLDR-AGLDAKALRMLSSEIATLECVHHP 125
            :||.|.....:|.|.|.|||:.:|:.|:.|||:|:::..: ..||  .:..:..||..|....||
 Worm    83 KIGHYILKETLGVGTFGKVKVGIHETTQYKVAVKILNRQKIKSLD--VVGKIRREIQNLSLFRHP 145

  Fly   126 NILRLFEVVETLGRVYLVTEWIRGGELYNHITQGGPLREIHAAPLLKQLLLAVKHMHSLGYVHRD 190
            :|:||::|:.|...::::.|.:.||||:::|.:.|.|:...|....:|::..|.:.|....||||
 Worm   146 HIIRLYQVISTPSDIFMIMEHVSGGELFDYIVKHGRLKTAEARRFFQQIISGVDYCHRHMVVHRD 210

  Fly   191 IKAENVLLLSEDRLKLADFGFSTQLINGANQKLDTFCGSPPYAAPELFSDDHYIGAPVDVWALGI 255
            :|.||:||..::.:|:||||.|..:.:|  ..|.|.||||.|||||:.|...|.|..||||:.|:
 Worm   211 LKPENLLLDEQNNVKIADFGLSNIMTDG--DFLRTSCGSPNYAAPEVISGKLYAGPEVDVWSCGV 273

  Fly   256 LLYFMVVGNMPFRAPTIPGLKAAILKGDYLLPGQLSLPCIRLIQRILIHIPAQRPTIDDMLNSQF 320
            :||.::.|.:||....:|.|...|..|.:..|..|..|.:.|:..:|...|.:|.||.|::..::
 Worm   274 ILYALLCGTLPFDDEHVPSLFRKIKSGVFPTPDFLERPIVNLLHHMLCVDPMKRATIKDVIAHEW 338

  Fly   321 VTCPKLSADLMQWEINQHTKPVKRSIFWVRSKSHRLRKSASLRDRYAEVVKKPAISMNTRQQDEM 385
                 ...||.    |....|:..|             .||:.|  .|.|::..........:|.
 Worm   339 -----FQKDLP----NYLFPPINES-------------EASIVD--IEAVREVTEFQRYHVAEEE 379

  Fly   386 FVQNFLQPIEMGHELLVPVSSQLKEPQSTEQAKRPTRRYMFCGSLKKKVTPMETEPEKQLANGGQ 450
             |.:.|...:..|.|.:..:..:...:..::..:.:....:..:..|...|:...||:..|:
 Worm   380 -VTSALLGDDPHHHLSIAYNLIVDNKRIADETAKLSIEEFYQVTPNKGPGPVHRHPERIAAS--- 440

  Fly   451 SIGSAKINPWNVEVAEDCPLFKNYDAETGSCVMLPTNTEDLSQLGALEFEARQILAELGLTSEML 515
              .|:||.| .::..|.....:|..|:....:...:..||:.      ||..:.:.:|.:..::|
 Worm   441 --VSSKITP-TLDNTEASGANRNKRAKWHLGIRSQSRPEDIM------FEVFRAMKQLDMEWKVL 496

  Fly   516 ------INARQSGPRSD----IIGAYRIVVNRLQKQSWL-----------------ARKHVEMAL 553
                  :..:...|.:|    .:..|::     .::|:|                 :.:|..|::
 Worm   497 NPYHVIVRRKPDAPAADPPKMSLQLYQV-----DQRSYLLDFKSLADEESGSASASSSRHASMSM 556

  Fly   554 HSEP 557
            ..:|
 Worm   557 PQKP 560

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG4629	NP_608564.3	STKc_NIM1	63..321	CDD:270977	93/258 (36%)
aak-2	NP_510710.2	STKc_AMPK_alpha	84..339	CDD:270981	93/263 (35%)
		UBA_AID_AMPKalpha	356..419	CDD:270521	10/65 (15%)
		AMPKA_C	462..624	CDD:213378	15/110 (14%)