Protein Alignment CG4629 and AMPKalpha

DIOPT Version :10

• Sequence 1: NP_608564.3
• Gene: CG4629 / 33284
• FlyBaseID: FBgn0031299
• Length: 570
• Species: Drosophila melanogaster
• Sequence 2: XP_312237.4
• Gene: AMPKalpha / 1273276
• VectorBaseID: AGAMI1_005037
• Length: 565
• Species: Anopheles gambiae
• Alignment Length: 538
• Identity: 142/538 - (26%)
• Similarity: 245/538 - (45%)
• Gaps: 95/538 - (17%)

  Fly    62 RIGLYRFCGDIGRGNFSKVKLAVHQLTRDKVAIKVVDLDR-AGLDAKALRMLSSEIATLECVHHP 125
            :||.|.....:|.|:|.|||:..||:|:.|||:|:::..: ..||  .:..:..||..|:...||
Mosquito    17 KIGHYILGATLGTGSFGKVKIGEHQVTKHKVAVKILNRQKIKSLD--VVGKIRREIQNLKLFRHP 79

  Fly   126 NILRLFEVVETLGRVYLVTEWIRGGELYNHITQGGPLREIHAAPLLKQLLLAVKHMHSLGYVHRD 190
            :|::|::|:.|...::::.|::.||||:::|.:.|.|:|..|....:|::..|.:.|....||||
Mosquito    80 HIIKLYQVISTPTDIFMIMEYVSGGELFDYIVKNGKLQESEARRFFQQIISGVDYCHRHMIVHRD 144

  Fly   191 IKAENVLLLSEDRLKLADFGFSTQLINGANQKLDTFCGSPPYAAPELFSDDHYIGAPVDVWALGI 255
            :|.||:||.....:|:||||.|..:::|  :.|.|.||||.|||||:.|...|.|..||:|:.|:
Mosquito   145 LKPENLLLDHNRHVKIADFGLSNMMLDG--EFLRTSCGSPNYAAPEVISGKLYAGPEVDIWSCGV 207

  Fly   256 LLYFMVVGNMPFRAPTIPGLKAAILKGDYLLPGQLSLPCIRLIQRILIHIPAQRPTIDDMLNSQF 320
            :||.::.|.:||....:|.|...|..|.:.:|..|:...:.|:.::|...|.:|.|::::...::
Mosquito   208 ILYALLCGTLPFDDEHVPTLFRKIKSGVFPIPEYLNKQVVSLLCQMLQVDPLKRATVEEIKKHEW 272

  Fly   321 VTCPKLSADLMQWEINQHTKPV----------KRSIFWVRSKSHRLRKSASLRDRYAEV-VKKPA 374
            .. ..|.|.|....:.|.:..|          |.|:     |.|.:..:....|.:.:: :....
Mosquito   273 FQ-KDLPAYLFPSPVEQDSSVVDTNAIREVCEKFSV-----KEHEVHNALLSGDPHDQLAIAYHL 331

  Fly   375 ISMNTRQQDEMFVQNFLQPIEMGHELLVPVSSQLKE-------PQSTEQAKRPTRRYMFCGSLKK 432
            |..|.|..||                  ...::|||       |.....:|..|.  :..||:..
Mosquito   332 IIDNKRIADE------------------AAKAELKEFYVAGSPPPPGADSKFGTP--LGPGSIAP 376

  Fly   433 KVTPMETEPEKQLANGGQSIGSAKINPWNVEVAEDCPLFKNYDAETGSCVMLPTNTEDLSQLGAL 497
            ......:||.|..:...:.|...:..|  |..|::.|              :|| ...:|....:
Mosquito   377 TQAGTPSEPFKSPSIHPERIAPLRERP--VTAAQNMP--------------VPT-LSTMSPSAVM 424

  Fly   498 EFE------ARQILAELGLTSEMLINARQSGPRSDIIGAYRI---------VVN----RLQKQSW 543
            ..:      .::....||:.|       ||.|...::..||.         ::|    |::|.:.
Mosquito   425 PIDKHRGTPVKRAKWHLGIRS-------QSKPNDIMLEVYRAMKALDFEWKIINPYHVRVRKYNA 482

  Fly   544 LARKHVEMAL---HSEPK 558
            ...|||:|:|   ..:||
Mosquito   483 RNDKHVKMSLQLYQVDPK 500

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG4629	NP_608564.3	STKc_NIM1	63..321	CDD:270977	90/258 (35%)
AMPKalpha	XP_312237.4	STKc_AMPK_alpha	18..273	CDD:270981	90/258 (35%)
		UBA_AID_AMPKalpha	290..354	CDD:270521	14/86 (16%)
		AMPKA_C	436..563	CDD:213378	18/72 (25%)