DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Atg4a and AT2G44140

DIOPT Version :9

Sequence 1:	NP_608563.1	Gene:	Atg4a / 33283	FlyBaseID:	FBgn0031298	Length:	411	Species:	Drosophila melanogaster
Sequence 2:	NP_001324765.1	Gene:	AT2G44140 / 819020	AraportID:	AT2G44140	Length:	467	Species:	Arabidopsis thaliana

Alignment Length:	405	Identity:	121/405 - (29%)
Similarity:	183/405 - (45%)	Gaps:	73/405 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly     6 SDQLARIMESVFEAYLGPDSVLASAVGQAVGSGEPEDIPRRNTDVWVLGKKYNAIQE-------- 62
            |..:.|..|.|    |||:..               .:|...:|||:||..|....:
plant    86 SGAIRRFQERV----LGPNRT---------------GLPSTTSDVWLLGVCYKISADENSGETDT 131

  Fly    63 ---LELIRRDIQSRLWCTYRHGFSPLGEVQLTTDKGWGCMLRCGQMVLAQALIDLHLGRDWFWTP 124
               |..::.|..|::..|||.||.|..:...|:|..||||:|..||:.||||:...|||.|....
plant   132 GTVLAALQLDFSSKILMTYRKGFEPFRDTTYTSDVNWGCMIRSSQMLFAQALLFHRLGRAWTKKS 196

  Fly   125 DCRDATYLKIVNRFEDVRNSFYSIHQIAQMGESQNKAVGEWLGPNTVAQ-----ILKKLVRFDDW 184
            :..:..||:.:..|.|...|.:|||.:...|.|...|.|.|:||..:.:     ..||..:.|..
plant   197 ELPEQEYLETLEPFGDSEPSAFSIHNLIIAGASYGLAAGSWVGPYAICRAWESLACKKRKQTDSK 261

  Fly   185 SS---LAIHVAMDS---------TVVLDDVYASCRE---GGS-WKPLLLIIPLRLGITDINPLYV 233
            :.   :|:|:...|         .:.::|...||.|   |.| |.|::|::||.||:..:||.|:
plant   262 NQTLPMAVHIVSGSEDGERGGAPILCIEDATKSCLEFSKGQSEWTPIILLVPLVLGLDSVNPRYI 326

  Fly   234 PALKRCLELDSSCGMIGGRPNQALYFLGYVDDEVLYLDPHTTQRTGAVAQKTAAAEQDYD-ETYH 297
            |:|........|.|::||:|..:.|.:|..:|:..|||||..|:...|.::|    .|.| .:||
plant   327 PSLVATFTFPQSVGILGGKPGASTYIVGVQEDKGFYLDPHEVQQVVTVNKET----PDVDTSSYH 387

  Fly   298 QKHAARLNFSAMDPSLAVCFLCKTSDSFESL---LTKLKEEVLSLCSPALFEISQTRAV------ 353
            ......:...::|||||:.|.|:..|.|:..   ..||.||  |..:| ||.::||...
plant   388 CNVLRYVPLESLDPSLALGFYCRDKDDFDDFCLRALKLAEE--SNGAP-LFTVTQTHTAINQSNY 449

  Fly   354 -----DWDTTEDIDW 363
                 |.:...:.||
plant   450 GFADDDSEDEREDDW 464

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Atg4a	NP_608563.1	Peptidase_C54	66..328	CDD:281417	93/283 (33%)
AT2G44140	NP_001324765.1	None

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2674
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H70873
Inparanoid	1	1.050	181	1.000	Inparanoid score	I1452
OMA	1	1.010	-	-		QHG55011
OrthoDB	1	1.010	-	-		D431748at2759
OrthoFinder	1	1.000	-	-		FOG0000466
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100501
Panther	1	1.100	-	-	O	PTHR22624
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X289
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	12	11.840