DRSC/TRiP Functional Genomics Resources

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Protein Alignment Atg4a and atg4a

DIOPT Version :10

Sequence 1:NP_608563.1 Gene:Atg4a / 33283 FlyBaseID:FBgn0031298 Length:411 Species:Drosophila melanogaster
Sequence 2:NP_001016619.1 Gene:atg4a / 549373 XenbaseID:XB-GENE-922674 Length:395 Species:Xenopus tropicalis


Alignment Length:416 Identity:165/416 - (39%)
Similarity:232/416 - (55%) Gaps:67/416 - (16%)


- Green bases have known domain annotations that are detailed below.


  Fly     5 LSDQLARIMESVFEAYLGPDSVLASAVGQAVGSGEPEDIPRRNTDVWVLGKKYNAIQELELIRRD 69
            :||.|....|.:.| ||                 :.|::|..:..|::|||:|:...|...::.|
 Frog     6 VSDYLKHENEPILE-YL-----------------DLEELPDSDEPVYILGKQYDMKTEKCNLQSD 52

  Fly    70 IQSRLWCTYRHGFSPLGEVQLTTDKGWGCMLRCGQMVLAQALIDLHLGRDWFWT-----PDCRDA 129
            |.||||.|||..|||:|....::|.|||||||||||:||||||..||||||.|.     |:    
 Frog    53 IVSRLWFTYRKKFSPIGGTGPSSDAGWGCMLRCGQMMLAQALICQHLGRDWRWEKHKEHPE---- 113

  Fly   130 TYLKIVNRFEDVRNSFYSIHQIAQMGESQNKAVGEWLGPNTVAQILKKLVRFDDWSSLAIHVAMD 194
            .|.:|:..|.|.::..|||||:||||..:.|::|||.|||||||:||||..||:|:|||::|:||
 Frog   114 EYRQILQCFLDRKDCCYSIHQMAQMGVGEGKSIGEWFGPNTVAQVLKKLALFDEWNSLAVYVSMD 178

  Fly   195 STVVLDDVYASCR--------------------------EGGSWKPLLLIIPLRLGITDINPLYV 233
            :|||::|:...|:                          :...|:|||||:||||||..|||:||
 Frog   179 NTVVIEDIKTMCKYQPHSCSMAQAASYQSTWSRCRDASGQSSGWRPLLLIVPLRLGINHINPVYV 243

  Fly   234 PALKRCLELDSSCGMIGGRPNQALYFLGYVDDEVLYLDPHTTQRTGAVAQKTAAAEQDYDETYH- 297
            .|.|.|.::..|.|.:||:||.|.||:|:..||::||||||||        |....:|.|:||| 
 Frog   244 DAFKACFKMPQSLGALGGKPNHAYYFIGFSGDEIIYLDPHTTQ--------TFVDTEDQDQTYHC 300

  Fly   298 QKHAARLNFSAMDPSLAVCFLCKTSDSFESLLTKLKEEVLSLCSPALFEISQTRAVDWDTTEDID 362
            ||....:....:|||:|:.|.||..:.|::....:::|:|...|..:||::......|.....  
 Frog   301 QKGPNSMKVLNLDPSVALGFFCKDENDFDNWCEVIEKEILKHQSLRMFELTPKHPPHWPPFIP-- 363

  Fly   363 WPTMPDIDWPAG--TSDSDSFAIVEE 386
             ||.|::.....  ...:|....|||
 Frog   364 -PTKPEVTTTGAELIESTDKLFDVEE 388

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Atg4aNP_608563.1 Peptidase_C54 63..328 CDD:460915 137/296 (46%)
atg4aNP_001016619.1 Peptidase_C54 46..333 CDD:460915 137/298 (46%)

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