Protein Alignment Atg4a and atg4c

DIOPT Version :9

• Sequence 1: NP_608563.1
• Gene: Atg4a / 33283
• FlyBaseID: FBgn0031298
• Length: 411
• Species: Drosophila melanogaster
• Sequence 2: NP_001002103.1
• Gene: atg4c / 415193
• ZFINID: ZDB-GENE-040625-84
• Length: 463
• Species: Danio rerio
• Alignment Length: 437
• Identity: 132/437 - (30%)
• Similarity: 200/437 - (45%)
• Gaps: 117/437 - (26%)

  Fly    46 RNTDVWVLGKKYN---------------AIQE------LELIRRDIQSRLWCTYRHGFSPLGEVQ 89
            ||:.|::|||.|:               |:.:      ::..|:|..||:|.|||..|..|....
Zfish    37 RNSPVFLLGKCYHFKVVDDENPTESTAEALDDDVVTGNVDEFRKDFTSRVWLTYREEFPALPGSS 101

  Fly    90 LTTDKGWGCMLRCGQMVLAQALIDLH-LGRDWFWT------------------------------ 123
            .|:|.||||.||.|||:|||||: || |||||.|:
Zfish   102 FTSDCGWGCTLRAGQMILAQALL-LHILGRDWKWSEALSLEPLDTETWTSSAARRLVATLEASIQ 165

  Fly   124 --------PDC------RDA-TYLK------IVNRFEDVRNSFYSIHQIAQMGESQNKAVGEWLG 167
                    |.|      .:| :|||      ||:.|.|..::...|:::.::|.:..|..|:|.|
Zfish   166 GERAQASQPLCPVQGEAEEADSYLKETYHRTIVSWFGDGPSAQLGIYKLVELGMTSGKQAGDWYG 230

  Fly   168 PNTVAQILKKLVRFDD-----WSSLAIHVAMDSTVVLDDVYAS-------------CREGGS--W 212
            |..||.||:|.|  |:     ...:.::||.|.||...||..|             ...|.|  .
Zfish   231 PAVVAHILRKAV--DEAVDAMLKGIRVYVAQDCTVYSADVIDSHSTRTESHSDPQGLDSGASPDS 293

  Fly   213 KPLLLIIPLRLGITDINPLYVPALKRCLELDSSCGMIGGRPNQALYFLGYVDDEVLYLDPHTTQR 277
            :.::::||:|||...|||.|:..:|..|.|:...|:|||:|.||.||:|:.||.::|:|||..|.
Zfish   294 RAVVILIPVRLGGEKINPEYLNFVKSILSLEYCIGIIGGKPKQAYYFVGFQDDSLIYMDPHYCQS 358

  Fly   278 TGAVAQKTAAAEQDYD-ETYHQKHAARLNFSAMDPSLAVCFLCKTSDSFESLLTKLKEEVLSLCS 341
            ...|      :..|:. :::|.....:::||.||||..:.|..|:.:.||    |:..|:..:..
Zfish   359 FVDV------STSDFPLQSFHCPSPKKMSFSKMDPSCTIGFYSKSVEHFE----KIANELSKILQ 413

  Fly   342 PA------LFEISQTRAVDWD---TTEDIDWPTMPDIDWPAGTSDSD 379
            |:      .|.|.:....|::   ..|..:||.:.|.. .|||:..|
Zfish   414 PSSKEKYPAFTIMKGHGKDYELSIAVEKREWPFIRDAR-KAGTTSGD 459

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Atg4a	NP_608563.1	Peptidase_C54	66..328	CDD:281417	110/334 (33%)
atg4c	NP_001002103.1	Peptidase_C54	76..407	CDD:281417	111/343 (32%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2674
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG55011
OrthoDB	1	1.010	-	-		D332531at33208
OrthoFinder	1	1.000	-	-		FOG0000466
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100501
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R109
SonicParanoid	1	1.000	-	-		X289
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	9	8.760