Protein Alignment Atg4a and atg-4.2

DIOPT Version :9

• Sequence 1: NP_608563.1
• Gene: Atg4a / 33283
• FlyBaseID: FBgn0031298
• Length: 411
• Species: Drosophila melanogaster
• Sequence 2: NP_502208.1
• Gene: atg-4.2 / 3565022
• WormBaseID: WBGene00014080
• Length: 521
• Species: Caenorhabditis elegans
• Alignment Length: 323
• Identity: 110/323 - (34%)
• Similarity: 172/323 - (53%)
• Gaps: 44/323 - (13%)

  Fly    49 DVWVLGKKYN-AIQE------LELIRRDIQSRLWCTYRHGFSPLGEVQLTTDKGWGCMLRCGQMV 106
            ||..||::|: ::.|      .|....|..||||.|||..|..|.:...|||.|||||:|..||:
 Worm   147 DVVFLGRRYSTSVDESGLRSGFENFCSDYYSRLWITYRTDFPALLDTDTTTDCGWGCMIRTTQMM 211

  Fly   107 LAQALIDLHLGRDWFWT------------PDCRDATYLK---IVNRFEDVRNSFYSIHQ---IAQ 153
            :|||::....||||.:|            .|..|...::   |:..|||...:...||:   ||.
 Worm   212 VAQAIMVNRFGRDWRFTRRKRSHVAAHGDEDDFDREKIQEWMILKLFEDKPTAPLGIHKMVGIAA 276

  Fly   154 MGESQNKAVGEWLGPNTVAQILKKLVRFDDWSSLAIHVAM----DSTVVLDDVYASCREGGSW-K 213
            ||:.: ||||.|..|:....|:||.:. :..|.|..:.||    |..|.:.|:..   |..:| |
 Worm   277 MGKGK-KAVGSWYSPSEAVFIMKKALT-ESSSPLTGNTAMLLSIDGRVHIRDIEV---ETKNWMK 336

  Fly   214 PLLLIIPLRLGITDINPLYVPALKRCLELDSSCGMIGGRPNQALYFLGYVDDEVLYLDPHTTQ-- 276
            .|:|:|.:|||..::||:|||.|.|...::|..|:.||||:.:.:|:||..|:::|||||...
 Worm   337 KLILVIVVRLGAAELNPIYVPHLMRLFAMESCLGITGGRPDHSSWFVGYYGDQIIYLDPHVAHEY 401

  Fly   277 -------RTGAVAQKTAAAEQDYDETYHQKHAARLNFSAMDPSLAVCFLCKTSDSFESLLTKL 332
                   .|..|...:..|::..:::||.:..::::|..||||.|:||..::.:.|::.:.:|
 Worm   402 IPIDINPNTNVVDSDSKKAKKCPEKSYHCRLLSKMHFFDMDPSCALCFQFESREQFDNDMRQL 464

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Atg4a	NP_608563.1	Peptidase_C54	66..328	CDD:281417	102/293 (35%)
atg-4.2	NP_502208.1	Peptidase_C54	168..459	CDD:367485	103/295 (35%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2674
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG55011
OrthoDB	1	1.010	-	-		D332531at33208
OrthoFinder	1	1.000	-	-		FOG0000466
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100501
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R109
SonicParanoid	1	1.000	-	-		X289
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	8	7.760