Protein Alignment Atg4a and Atg4b

DIOPT Version :9

• Sequence 1: NP_608563.1
• Gene: Atg4a / 33283
• FlyBaseID: FBgn0031298
• Length: 411
• Species: Drosophila melanogaster
• Sequence 2: XP_006245595.1
• Gene: Atg4b / 316640
• RGDID: 1309664
• Length: 393
• Species: Rattus norvegicus
• Alignment Length: 347
• Identity: 158/347 - (45%)
• Similarity: 210/347 - (60%)
• Gaps: 48/347 - (13%)

  Fly    39 EPEDIPRRNTDVWVLGKKYNAIQELELIRRDIQSRLWCTYRHGFSPLGEVQLTTDKGWGCMLRCG 103
            |.||.|..:..||:||:||:...|.:.|..|:.||||.|||..|..:|....|:|.|||||||||
  Rat    15 EFEDFPETSEPVWILGRKYSIFTEKDEILSDVASRLWFTYRRNFPAIGGTGPTSDTGWGCMLRCG 79

  Fly   104 QMVLAQALIDLHLGRDWFWT-----PDCRDATYLKIVNRFEDVRNSFYSIHQIAQMGESQNKAVG 163
            ||:.||||:..||||||.||     ||    :|..::|.|.|.::|:||||||||||..:.|::|
  Rat    80 QMIFAQALVCRHLGRDWRWTQRKRQPD----SYFSVLNAFLDRKDSYYSIHQIAQMGVGEGKSIG 140

  Fly   164 EWLGPNTVAQILKKLVRFDDWSSLAIHVAMDSTVVLDDVYASCR--------------------- 207
            :|.|||||||:||||..||.|||||:|:|||:|||::::...||
  Rat   141 QWYGPNTVAQVLKKLAVFDTWSSLAVHIAMDNTVVMEEIRRLCRASLPCAGAAALSMESERHCNG 205

  Fly   208 --EGG-------SWKPLLLIIPLRLGITDINPLYVPALKRCLELDSSCGMIGGRPNQALYFLGYV 263
              .|.       :|:||:|:||||||:||||..||..||.|..:..|.|:|||:||.|.||:|||
  Rat   206 LPAGAEVTNRPLAWRPLVLLIPLRLGLTDINEAYVETLKHCFMMPQSLGVIGGKPNSAHYFIGYV 270

  Fly   264 DDEVLYLDPHTTQRTGAVAQKTAAAEQDYDETYHQKH-AARLNFSAMDPSLAVCFLCKTSDSFES 327
            .:|::||||||||....:.......    ||::|.:| ..|:....:|||:||.|.|||.:.|..
  Rat   271 GEELIYLDPHTTQPAVELTDSCFIP----DESFHCQHPPCRMGIGELDPSIAVGFFCKTEEDFND 331

  Fly   328 LLTKLKEEVLSLCSPAL--FEI 347
            ...::|:  ||....||  ||:
  Rat   332 WCQQVKK--LSQLGGALPMFEL 351

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Atg4a	NP_608563.1	Peptidase_C54	66..328	CDD:281417	140/297 (47%)
Atg4b	XP_006245595.1	Peptidase_C54	40..335	CDD:281417	140/302 (46%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166341340
Domainoid	1	1.000	277	1.000	Domainoid score	I1659
eggNOG	1	0.900	-	-		E1_KOG2674
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	302	1.000	Inparanoid score	I2594
OMA	1	1.010	-	-		QHG55011
OrthoDB	1	1.010	-	-		D332531at33208
OrthoFinder	1	1.000	-	-		FOG0000466
OrthoInspector	1	1.000	-	-		otm45755
orthoMCL	1	0.900	-	-		OOG6_100501
Panther	1	1.100	-	-	LDO	PTHR22624
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X289
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	14	13.770