Protein Alignment Atg4a and Atg4c

DIOPT Version :9

• Sequence 1: NP_608563.1
• Gene: Atg4a / 33283
• FlyBaseID: FBgn0031298
• Length: 411
• Species: Drosophila melanogaster
• Sequence 2: NP_001101418.1
• Gene: Atg4c / 313391
• RGDID: 1598323
• Length: 458
• Species: Rattus norvegicus
• Alignment Length: 413
• Identity: 126/413 - (30%)
• Similarity: 181/413 - (43%)
• Gaps: 108/413 - (26%)

  Fly    46 RNTDVWVLGKKYN----------------AIQE------LELIRRDIQSRLWCTYRHGFSPLGEV 88
            ||:.|.:|||.|:                ||::      :|..|:|..||:|.|||..|..:...
  Rat    37 RNSPVLLLGKCYHFKYEDESKVLPARSGCAIEDHVIAGNVEEFRKDFISRIWLTYREEFPQIEAS 101

  Fly    89 QLTTDKGWGCMLRCGQMVLAQALIDLHLGRDWFWTPDC--------------------------- 126
            .||||.||||.||.|||:|||.||...|||.|.| ||.
  Rat   102 ALTTDCGWGCTLRTGQMLLAQGLILHFLGRAWTW-PDALHIESSDSDSWTSNTIHKFTASFEASL 165

  Fly   127 -------RDATYLK--------------------IVNRFEDVRNSFYSIHQIAQMGESQNKAVGE 164
                   ..|..||                    |::.|.|...:.:.:|::.:.|:...|..|:
  Rat   166 SGERELRTPAVSLKETSGKHPDDHAVQSEIYHRQIISWFGDSPVAVFGLHRLIEFGKKSGKKAGD 230

  Fly   165 WLGPNTVAQILKKLV---RFDDWSSLAIHVAMDSTV----VLDDVYASCREGGSW-KPLLLIIPL 221
            |.||..||.||:|.|   |..|...|.|:||.|.||    |:|....|...|.:. |.:::::|:
  Rat   231 WYGPAVVAHILRKAVEEARHPDLQGLTIYVAQDCTVYNSDVIDKQTDSVTAGDARDKAVIILVPV 295

  Fly   222 RLGITDINPLYVPALKRCLELDSSCGMIGGRPNQALYFLGYVDDEVLYLDPHTTQRTGAVAQKTA 286
            |||....|..|:..:|..|.|:...|:|||:|.|:.||.|:.||.::|:|||..|....|:.|
  Rat   296 RLGGERTNIDYLEFVKGVLSLEYCVGIIGGKPKQSYYFAGFQDDSLIYMDPHYCQSFVDVSIK-- 358

  Fly   287 AAEQDYD-ETYHQKHAARLNFSAMDPSLAVCFLCKTSDSFESLLTKLKEEVLSLCSPA------L 344
                |:. ||:|.....:::|..||||..:.|.|:....||    :..||:..:...:      |
  Rat   359 ----DFPLETFHCPSPKKMSFRKMDPSCTIGFYCRNVQDFE----RASEEITKMLKISSKEKYPL 415

  Fly   345 FEISQTRAVDWDTT------EDI 361
            |......:.|:|.|      ||:
  Rat   416 FTFVNGHSRDFDFTSTAASEEDL 438

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Atg4a	NP_608563.1	Peptidase_C54	66..328	CDD:281417	107/324 (33%)
Atg4c	NP_001101418.1	Peptidase_C54	76..395	CDD:397471	106/325 (33%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2674
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG55011
OrthoDB	1	1.010	-	-		D332531at33208
OrthoFinder	1	1.000	-	-		FOG0000466
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100501
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X289
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	8	7.730