Protein Alignment Atg4a and Atg4c

DIOPT Version :9

• Sequence 1: NP_608563.1
• Gene: Atg4a / 33283
• FlyBaseID: FBgn0031298
• Length: 411
• Species: Drosophila melanogaster
• Sequence 2: NP_001139439.1
• Gene: Atg4c / 242557
• MGIID: 2651854
• Length: 458
• Species: Mus musculus
• Alignment Length: 428
• Identity: 128/428 - (29%)
• Similarity: 185/428 - (43%)
• Gaps: 115/428 - (26%)

  Fly    46 RNTDVWVLGKKYN----------------AIQE------LELIRRDIQSRLWCTYRHGFSPLGEV 88
            ||:.|.:|||.|:                ||::      :|..|:|..||:|.|||..|..:...
Mouse    37 RNSPVLLLGKCYHFKYEDESKMLPARSGCAIEDHVIAGNVEEFRKDFISRIWLTYREEFPQIEAS 101

  Fly    89 QLTTDKGWGCMLRCGQMVLAQALIDLHLGRDWFWTPD---------------------------- 125
            .||||.||||.||.|||:|||.||...|||.|.| ||
Mouse   102 ALTTDCGWGCTLRTGQMLLAQGLILHFLGRAWTW-PDALHIENADSDSWTSNTVKKFTASFEASL 165

  Fly   126 -------------------CRD-------ATYLKIVNRFEDVRNSFYSIHQIAQMGESQNKAVGE 164
                               |.|       |.:.||::.|.|...:.:.:|::.:.|:...|..|:
Mouse   166 SGDRELRTPAVSLKETSGKCPDDHAVRNEAYHRKIISWFGDSPVAVFGLHRLIEFGKKSGKKAGD 230

  Fly   165 WLGPNTVAQILKKLV---RFDDWSSLAIHVAMDSTV----VLDDVYASCREGGSW-KPLLLIIPL 221
            |.||..||.||:|.|   |..|...|.|:||.|.||    |:|....|...|.:. |.:::::|:
Mouse   231 WYGPAVVAHILRKAVEEARHPDLQGLTIYVAQDCTVYNSDVIDKQTDSVTAGDARDKAVIILVPV 295

  Fly   222 RLGITDINPLYVPALKRCLELDSSCGMIGGRPNQALYFLGYVDDEVLYLDPHTTQRTGAVAQKTA 286
            |||....|..|:..:|..|.|:...|:|||:|.|:.||.|:.||.::|:|||..|....|:.|
Mouse   296 RLGGERTNTDYLEFVKGVLSLEYCVGIIGGKPKQSYYFAGFQDDSLIYMDPHYCQSFVDVSIK-- 358

  Fly   287 AAEQDYD-ETYHQKHAARLNFSAMDPSLAVCFLCKTSDSFESLLTKLKEEVLSLCSPA------L 344
                |:. ||:|.....:::|..||||..:.|.|:....||    :..||:..:...:      |
Mouse   359 ----DFPLETFHCPSPKKMSFRKMDPSCTIGFYCRNVQDFE----RASEEITKMLKISSKEKYPL 415

  Fly   345 FEISQTRAVDWDTTEDIDWPTMPDIDWPAGTSDSDSFA 382
            |......:.|:|.|.             ...|:.|.|:
Mouse   416 FTFVNGHSKDFDFTS-------------TAASEEDLFS 440

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Atg4a	NP_608563.1	Peptidase_C54	66..328	CDD:281417	108/324 (33%)
Atg4c	NP_001139439.1	Peptidase_C54	77..395	CDD:281417	107/324 (33%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2674
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG55011
OrthoDB	1	1.010	-	-		D332531at33208
OrthoFinder	1	1.000	-	-		FOG0000466
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100501
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R109
SonicParanoid	1	1.000	-	-		X289
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	8	7.760