Protein Alignment Atg4a and atg-4.1

DIOPT Version :9

• Sequence 1: NP_608563.1
• Gene: Atg4a / 33283
• FlyBaseID: FBgn0031298
• Length: 411
• Species: Drosophila melanogaster
• Sequence 2: NP_001368160.1
• Gene: atg-4.1 / 190777
• WormBaseID: WBGene00013595
• Length: 481
• Species: Caenorhabditis elegans
• Alignment Length: 460
• Identity: 160/460 - (34%)
• Similarity: 231/460 - (50%)
• Gaps: 78/460 - (16%)

  Fly    10 ARIMESVFEAYLGPDSVLASAVGQAVG------SGEP------EDIPRRNTDVWVLGKKYNAIQE 62
            :||:: .||.....|.:....:.|.||      :.||      |.|...|..::.|||:.:....
 Worm    13 SRILQ-YFEQLPVVDKMTEEILKQGVGIVETSLTFEPPFCESFERISIDNFPIFALGKEISKEDG 76

  Fly    63 LELIRRDIQSRLWCTYRHGFSPLGEVQLTTDKGWGCMLRCGQMVLAQALIDLHLGRDWFWTPDCR 127
            :|.:::.:.||.|.|||..|||:|....:||:||||||||.||:|.:.|:..|:||.:.|..:..
 Worm    77 IEAMKKYVTSRFWFTYRRDFSPIGGTGPSTDQGWGCMLRCAQMLLGEVLLRRHIGRHFEWDIEKT 141

  Fly   128 DATYLKIVNRFEDVRNSFYSIHQIAQMGESQNKAVGEWLGPNTVAQILKKLVRFDDWSSLAIHVA 192
            ...|.||:..|.|.:::.||||||||||.::.|.|.:|.||||.||::|||..|||||::|:|||
 Worm   142 SEIYEKILQMFFDEKDALYSIHQIAQMGVTEGKEVSKWFGPNTAAQVMKKLTIFDDWSNIAVHVA 206

  Fly   193 MDSTVVLDDV------YAS------CREGG----------------SWKPLLLIIPLRLGITDIN 229
            :|:.:|.:|.      |.|      ..|.|                .|:||||:||||||:|.||
 Worm   207 LDNILVKEDAITMATSYPSEDAVKLIMENGLVDKNRLSLSPGNIIPEWRPLLLMIPLRLGLTTIN 271

  Fly   230 PLYVPALKRCLELDSSCGMIGGRPNQALYFLGYVDDEVLYLDPH----TTQRTGAV-AQKTAAAE 289
            |.|:.|::...::....|:||||||.||||:|....::.|||||    .|:.|..: |:|.:.|.
 Worm   272 PCYLSAIQEFFKIPQCVGIIGGRPNHALYFVGMSGSKLFYLDPHYCRPKTESTAKMYAEKDSTAT 336

  Fly   290 QD--------------------Y----DETYHQKHAARLNFSAMDPSLAVCFLCKTSDSFESLLT 330
            .|                    |    |.|||.:....:.:..:|||||:...|:|.|.||:|..
 Worm   337 TDDVGFSHLEELVPLPSQTADVYTKMDDSTYHCQMMLWIEYENVDPSLALAMFCETRDEFENLCE 401

  Fly   331 KLKEEVLSLCSPALFEISQTRAVDWDTTE-------DIDWPTMPDIDWPAGTSDSDSFAIVEESG 388
            .|::..|....|.:||..|.|.......|       .|:.....||. .|.....|.|.:::...
 Worm   402 TLQKTTLPASQPPMFEFLQRRPKYLPKFEPYTGVSMKIEMKEFDDIG-AANVKIDDDFEVLDVHT 465

  Fly   389 RDSDA 393
            .:.||
 Worm   466 EEEDA 470

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Atg4a	NP_608563.1	Peptidase_C54	66..328	CDD:281417	126/318 (40%)
atg-4.1	NP_001368160.1	Peptidase_C54	77..401	CDD:397471	128/323 (40%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160159546
Domainoid	1	1.000	231	1.000	Domainoid score	I1377
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H70873
Inparanoid	1	1.050	251	1.000	Inparanoid score	I1993
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG55011
OrthoDB	1	1.010	-	-		D332531at33208
OrthoFinder	1	1.000	-	-		FOG0000466
OrthoInspector	1	1.000	-	-		oto19627
orthoMCL	1	0.900	-	-		OOG6_100501
Panther	1	1.100	-	-	LDO	PTHR22624
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X289
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	14	13.870