Protein Alignment ast and fam120b

DIOPT Version :10

• Sequence 1: NP_523451.2
• Gene: ast / 33282
• FlyBaseID: FBgn0015905
• Length: 854
• Species: Drosophila melanogaster
• Sequence 2: NP_001429173.1
• Gene: fam120b / 445206
• ZFINID: ZDB-GENE-040801-119
• Length: 682
• Species: Danio rerio
• Alignment Length: 721
• Identity: 138/721 - (19%)
• Similarity: 228/721 - (31%)
• Gaps: 263/721 - (36%)

  Fly     1 MGVRGLTSY-------------IAQRAEIYLKPHELHSTALVIDGDNLSCNLYKDVTGSYSAFGG 52
            |||:||..:             :.|.|..:||.|...:.:||:|.  ::|..|.....:: ..||
Zfish     1 MGVKGLQYFMEVCCPDSCVPVDLKQMAGNHLKAHPDSTASLVVDA--MACLRYWYRCPAW-VHGG 62

  Fly    53 DYDDFYRAVVQFFQVLAECNIRPYVLMDGGYEERK-LRTVSTRLRNKISVIKKI--------NPN 108
            .:.::...:.:|........||.....||..|||| ...:..|||....:.|..        .||
Zfish    63 QWKEYINILQEFINAFTAAGIRLIFFFDGTVEERKRSEWIKRRLRVNQDIAKVFQHIKTHNQQPN 127

  Fly   109 A-SITLFPLHLKEVFVDAVRDCGVPVMRCVFEADDELAALARKLNC-PVLSYDSDFYIHNVKYIP 171
            : ::...|..|......|::..|......|.|.|.|:|..|...|| .:|..|:||.|:|.  :|
Zfish   128 SRNLFCLPSGLATFSRFALKSLGQETFCSVREGDYEVADYALSHNCMGILGQDTDFVIYNT--VP 190

  Fly   172 LITLTVKVLTKQVKDKNSSNQKDSRDLRHCEAKNVKKRTRANKIVTGIQTTGLTASTKGSSKTYK 236
            .:::                                     :|:.....||.|.:..|
Zfish   191 YLSI-------------------------------------SKLHLNSMTTVLFSREK------- 211

  Fly   237 YLDCCIYRVSHLCGRGTLSPEKLPLFAALLGNDYIARSAFKNFFAAGMGKAGRSRKLKLQQKRIQ 301
                       ||....|....|||.:.|||||.:.....:           |.|.:.|...|::
Zfish   212 -----------LCRVLQLHVHDLPLLSCLLGNDVVHEQQMQ-----------RLRNIALDSYRMK 254

  Fly   302 VILTWLKEETAES--ALAKVLSRLKKNQRD----SLVSQVNAAISGYSNELCHAYDYFDEHYENA 360
                 .||...:.  |.|:.::..|.:...    |.:|.|.|........:|
Zfish   255 -----CKEVQGDRVYAAAEFINIHKPSCEGTVGLSQLSLVKAEEEALERGIC------------- 301

  Fly   361 FPYIEP------------VSEEECSDDEHSSSSDEKFSDVEEGEDQEEADNQDEEQQE---ENQD 410
             .|:.|            .||..|:           .|:...|:..|.|..|....:.   .|..
Zfish   302 -MYLLPGQTSPWVKRSVWSSEPTCA-----------MSEFVAGDILEAAVEQHRRAESFFIYNVL 354

  Fly   411 VDSGDEEEEEADEGLELEVEDKTLLFPQWFLDKLYPAHLPRSFVDLMHLRKYINNPQIEHFPFHD 475
            .|...|.....::..|:|:..:.:|:
Zfish   355 YDGVVECSNTLEDEDEMELPPQAILY--------------------------------------- 380

  Fly   476 SNEVALPILNYVFALLHHVECEKIELPLEVDMDIEGSTVPYLTY-------LTRALRVT--NVRY 531
                 |||...::.:|         ||.|.|.  .|.||....:       |....|||  .:|:
Zfish   381 -----LPIRERIYGIL---------LPTEPDG--SGHTVSVKEWFVFPGNPLKEPTRVTPKPIRH 429

  Fly   532 FKMPIEKKPAYPFDPLSPDARHLRAVFEDNAPNADTEKLFSKLD-----QLPEDLRLYF----LA 587
            .|.|::                ||:|:....|...|.:..:.||     :..|:|: ||    :|
Zfish   430 LKGPLD----------------LRSVWFKTDPEVKTIRTSTLLDIFDLYEFTEELK-YFDSPLIA 477

  Fly   588 IIYWLHRSEHCDLLHLHSLILSLVVLRTIDVTIPAEREVKTFL--------KRFGKTLKAERAVR 644
            :|        |        :::.:.::|..:::   .:|..:|        |.|.:|.:....|.
Zfish   478 VI--------C--------LVTYIAIQTRQLSL---EDVDAYLSQAVCVRFKSFRETQQLRIPVV 523

  Fly   645 DKEAAE 650
            |..|.:
Zfish   524 DPRAVQ 529

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ast	NP_523451.2	PIN_asteroid-like	28..182	CDD:350243	41/164 (25%)
fam120b	NP_001429173.1	None