Protein Alignment ast and ast

DIOPT Version :10

• Sequence 1: NP_523451.2
• Gene: ast / 33282
• FlyBaseID: FBgn0015905
• Length: 854
• Species: Drosophila melanogaster
• Sequence 2: XP_061512838.1
• Gene: ast / 1278980
• VectorBaseID: AGAMI1_005189
• Length: 879
• Species: Anopheles gambiae
• Alignment Length: 916
• Identity: 318/916 - (34%)
• Similarity: 470/916 - (51%)
• Gaps: 100/916 - (10%)

  Fly     1 MGVRGLTSYIAQRAEIYLKPHELHSTALVIDGDNLSCNLYKDVTGSYSAFGGDYDDFYRAVVQFF 65
            |||||||::|.:.|.:||||||||.|.||||||||...|:|.......|.||:||.:||.||.||
Mosquito     1 MGVRGLTTFIEKNAAVYLKPHELHDTNLVIDGDNLCVQLFKRSQKVGFALGGNYDAYYRTVVDFF 65

  Fly    66 QVLAECNIRPYVLMDGGYEERKLRTVSTRLRNKISVIKKINPNASITLFPLHLKEVFVDAVRDCG 130
            .:|...|:.||||:|||||.||:..|..|::.:|..:|..:..|..:..|..|:||||||:|:.|
Mosquito    66 DMLQLVNVVPYVLLDGGYESRKIAIVRYRMQQRILKMKGFHVPAINSATPPMLREVFVDAMRESG 130

  Fly   131 VPVMRCVFEADDELAALARKLNCPVLSYDSDFYIHNVKYIPLITLTVKVLTKQVKDKNSSNQKDS 195
            |..|||.||||||:|.|||||.|||||||||||||:|:|||.:||:.||..| |.|:...|.|
Mosquito   131 VAFMRCAFEADDEVAILARKLGCPVLSYDSDFYIHDVQYIPYVTLSSKVYRK-VSDREGENFK-- 192

  Fly   196 RDLRHCEAKNVKKRTRANKIVTGIQTTG--LTASTKGSSKTYKYLDCCIYRVSHLCG-RGTLSPE 257
              :...|.|..||..:....|..|...|  .....:|..:||.|||||:|.:.:|.| ...|..|
Mosquito   193 --VGIVERKQTKKARQRGDGVRYIAQCGDQDVVEGEGEVETYSYLDCCLYNIDNLTGPHDQLGKE 255

  Fly   258 KLPLFAALLGNDYIARSAFKNFF-AAGMGKAGRSRKLKLQQKRIQVILTWLKEETAESALAKVLS 321
            .:||||.|||||||.|:..:.|: |...|:.  :||:..|::|::|||.||:..|.|||...::.
Mosquito   256 MIPLFAVLLGNDYIERNVLRAFYEAISTGRV--NRKINQQERRLKVILKWLQNHTFESATRAIIR 318

  Fly   322 RLKKNQRDSLVSQVNAAISGYSNELCHAYDYF--------------DEHYENAFPYIEPVSE--- 369
            .:|..|:..:..|:..||.||:.|.|.|..||              ||..::....:..:.|
Mosquito   319 HIKGEQKQQVYRQILTAIRGYNCEDCVALHYFGLQDQTEQETPLEDDEIEKDLQTRLGAIDEGEE 383

  Fly   370 --EECSDDE---HSSSSDEKFSDVEEGEDQEEADNQDEEQQ-----EENQDVDSGD--EEEEEAD 422
              ||..|:.   .|...:||.|...||::::..|:|::|..     :|..|.|..|  :||.:|:
Mosquito   384 TMEETVDEASFLDSEEEEEKESTSNEGQNEKSKDDQEDELSRHNSCDEEHDKDENDLLQEESDAE 448

  Fly   423 E----------GLEL---EVEDKTLLFPQWFLDKLYPAHLPRSFVDLMHLRKYINNPQIEHFPFH 474
            |          |.||   :..|:.  :|.||......|.:||...||:|...|||.||||.....
Mosquito   449 EIIMDGHEPLIGPELKRNKFTDRN--WPDWFKRIYSAAQVPRFLADLIHSNLYINYPQIEDVKRQ 511

  Fly   475 DSNEVALPILNYVFALLHHVECEKIELPLEVDMDIEGSTVPYLTYLTRALRVTNVRYFKMPIEKK 539
            |||.::.|||..|||:|              ....:..|..: .|:||.:..|.|....:.....
Mosquito   512 DSNRLSGPILRTVFAIL--------------KTSFKVKTTEF-KYVTRRVPGTGVVNATVTDACL 561

  Fly   540 PA-YPFDPLS-PDARHLRAVFEDNAPNADTEK---LFSKLDQLPEDLRLYFLAIIYWLHRSEHCD 599
            || ..:||.. |:...||.:|||    |..||   ||..:..:|.:|||||||||||.......:
Mosquito   562 PAGVEYDPAKLPNVTILRKLFED----AGIEKCDELFETIRSVPSNLRLYFLAIIYWAKNCPDVN 622

  Fly   600 LLHLHSLILSLVVLRTIDVTIPA-EREVKTFLKRFGKTLKAERAV-RDKEAAEGIKRGIKP-ALL 661
            |.::|:|::.::.|:.:|..:.: .|.|..|.:...:.|:.:|.. :..|.:.|     || ...
Mosquito   623 LAYVHALVVCILQLQIVDKALKSLNRNVDQFRQAHREYLEQQRQTSKTSEQSAG-----KPDVAF 682

  Fly   662 ELSVPDRMAH-VPKSDCYLTQERLLPHFHMQE---IFKKKFDLYSTTVIHAFAEFQAVVYQLNGL 722
            ..:..:::|. ..::...|..:.|:.||..:|   ..::|..:.:.| :|..|.||:|.:.|..|
Mosquito   683 NRTFYNKLASGTSRASALLAYDHLIQHFSYKEEEVRGRRKMWIEAGT-MHTLASFQSVCFNLYAL 746

  Fly   723 NSLLDFPLLSPRMNQLYCGAFLYNMYDVLRNRADVRYHVENFLLPDSKLMFDFYCYLYDWCAEFI 787
            ..||.:|:.:.||::||...|:||:|:.::|.||:..:....:...|..::...|.:..:...::
Mosquito   747 TPLLGYPVENLRMHELYNTLFVYNVYEGMKNLADLGEYERTVIFRHSATLYAAVCVMVRFVETYV 811

  Fly   788 PTWKRLEVDPTAAKALQKKRLKKQRQAARKVELREAIADPNAEMVEDADPEND----FFDLNNKF 848
            |..|...|.....||.:    :|::.......:....|:...|..:|...|:|    :.|:||||
Mosquito   812 PELKGRTVRAKTGKAAK----RKEQPVVHVQPITVRPANDWDEGKKDESSESDDGEGYVDVNNKF 872

  Fly   849 CALKVA 854
            ..|.:|
Mosquito   873 SQLLLA 878

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ast	NP_523451.2	PIN_asteroid-like	28..182	CDD:350243	86/153 (56%)
ast	XP_061512838.1	None