Protein Alignment ast and aste1

DIOPT Version :9

• Sequence 1: NP_523451.2
• Gene: ast / 33282
• FlyBaseID: FBgn0015905
• Length: 854
• Species: Drosophila melanogaster
• Sequence 2: NP_001121487.1
• Gene: aste1 / 100158587
• XenbaseID: XB-GENE-990630
• Length: 662
• Species: Xenopus tropicalis
• Alignment Length: 901
• Identity: 205/901 - (22%)
• Similarity: 313/901 - (34%)
• Gaps: 289/901 - (32%)

  Fly     1 MGVRGLTSYIAQRAEIYLKPH--ELHSTALVIDGDNLSCNLYKDVTGSYSAFGGDYDDFYRAVVQ 63
            ||::||..|:..:...:   |  :|.:|.::|||:||...||.: :|.....||||..|..||.:
 Frog     1 MGIQGLMGYVGSKKYCF---HDLQLRNTKIIIDGNNLYHRLYFE-SGLDLICGGDYHLFTDAVHK 61

  Fly    64 FFQVLAECNIRPYVLMDGGYE--ERKLRTVSTRLRNKISVIKKINPNASITLFPLHLKEVFVDAV 126
            ||:.|:.|.|..||:.|||.:  ::|..|:..|.:.||.:...::.....::.||.::|||:..:
 Frog    62 FFESLSVCEIHAYVVFDGGCDISDKKFETLKQRAKEKIIMAHSLSKGEGGSVLPLLVREVFIQVL 126

  Fly   127 RDCGVPVMRCVFEADDELAALARKLNCPVLSYDSDFYIHNVK--YIPLITLTVKVLTKQVKDKNS 189
            ....||.::|..|||.||..||....||||::||||.|.::|  :.||
 Frog   127 EKMEVPFVQCFAEADRELVVLANLWKCPVLTFDSDFCIFDLKAGFCPL----------------- 174

  Fly   190 SNQKDSRDLRHCEAKNVKKRTRANKIVTGIQTTGLTASTKGSSKTYKYLDCCI----YRVSHLCG 250
             |....|::...:.||                                 :|.|    |.....|.
 Frog   175 -NSFQWRNIVTAKEKN---------------------------------ECFIPAKCYSAQQFCK 205

  Fly   251 R-GTLSPEKLPLFAALLGNDYIARSAFKNFFAAGMGKAGRSRKLKLQQKRIQVILTWLKE-ETAE 313
            . ..::...|||||.|:|||||...|.:.||:......|.|.....:..|||.:|.||.. ..||
 Frog   206 HFNNMNMSLLPLFAVLVGNDYINLPALERFFSQVHLPIGNSCHSGRKHVRIQGLLHWLSAFADAE 270

  Fly   314 SALAKVLSRLKKNQRDSLVSQVNAAISGYSNELCHAYDYFD-------EHYENAFPYIEPVSEEE 371
            .|:..||..||...||: |.|:          ||.|.:.:.       ||:.....|..|.:
 Frog   271 EAMHNVLIYLKAQDRDT-VRQL----------LCSAMEEYSLSDTVNLEHFFQKGIYSSPAA--- 321

  Fly   372 CSDDEHSSSSDEKFSDVEEGEDQEEADNQDEEQQEENQDVDSGDEEEEEADEGLELEVEDKTLLF 436
                                                                     |..|   .
 Frog   322 ---------------------------------------------------------VMSK---L 326

  Fly   437 PQWFLDKLYPAHLPRSFVDLMHLRKYINNPQIEHFPFHDSNEVALPILNYVFALLHHVECEKIEL 501
            |.|....|....:.....|.:.|::...:.|:|......::.:..||...::.:|
 Frog   327 PNWVQRSLARGQISPLLRDALVLQRSFLHSQVEDMKKPSAHLITKPIRRVIYGML---------- 381

  Fly   502 PLEVDMDIEGSTVPYLTYLTRALRVTNVRYFKMPIEKKPAYPFDPLSPDARHLRAVFEDNAPNAD 566
                              ||..              |....||..|..:...|......:...||
 Frog   382 ------------------LTPT--------------KSNEPPFKGLIVEFDRLEKSLRKSTLEAD 414

  Fly   567 T-----EKL-FSKLDQLPEDLRLYFLAIIYWLHRSEHCDLLHLHSLILSLVVLRTIDVTIPAER- 624
            |     |.| .:.|.:.|..:||..|           .|.|.:.:.||:.|.        ||..
 Frog   415 THWNLAENLSLANLPEAPTQIRLKLL-----------LDTLEIKTAILASVP--------PAHHL 460

  Fly   625 --EVKTFLKRFGKTLKAERAVRDKEAAEGIKRGIKPALLELSVPDRMAHVPKSDCYLTQER---- 683
              .|..:..|:              |...:|.....|||..||...:     .|.:||.|.
 Frog   461 PVAVTCYWVRY--------------ADPKVKLHHLKALLMGSVCGEL-----YDMFLTAEGNSKD 506

  Fly   684 -LLPHFHMQEIFK--------KKFDLYSTTVIHAFAEFQAVVYQLNGLNSLLDFPLLSPRMNQLY 739
             |..|..:|:|.:        .|.|:      |.|.::|..:......|.||..|||.|.:.:||
 Frog   507 ILYVHEQLQKIIQGNPCRKIPNKEDM------HIFCQWQCCLQVGLHFNQLLCTPLLHPNIKRLY 565

  Fly   740 CGAFLYNMYDVLRNRADVRYHVENFLLPDSKLMFDFYCYLYDWCAEFI------PTWKRLEVDPT 798
            .|..::.:...|::...    :|:...|...|..     ||....|.:      ..:|...|..|
 Frog   566 NGTLVHLLCQKLKSSPS----IEDLFSPCPPLKM-----LYQQMLEAVILAVPEDCFKSRTVSST 621

  Fly   799 AAKALQKKRLKKQRQAARKVELREA-IADPNAEMVEDADPENDFFDLNNKFCALKV 853
            ....:.|||       .||||.:|. :|..|..|          :::.|:|.:|::
 Frog   622 HKSKMGKKR-------NRKVESKEVHLAVENQPM----------YEVTNRFVSLRL 660

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ast	NP_523451.2	XPG_I_2	115..>354	CDD:289575	71/246 (29%)
aste1	NP_001121487.1	PIN_SF	1..161	CDD:301351	58/163 (36%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	63	1.000	Domainoid score	I10106
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	165	1.000	Inparanoid score	I4071
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D200053at33208
OrthoFinder	1	1.000	-	-		FOG0006050
OrthoInspector	1	1.000	-	-		oto105086
Panther	1	1.100	-	-	LDO	PTHR15665
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X4965
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	7	7.160