DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment IA-2 and PTP1

DIOPT Version :9

Sequence 1:	NP_608562.4	Gene:	IA-2 / 33277	FlyBaseID:	FBgn0031294	Length:	1319	Species:	Drosophila melanogaster
Sequence 2:	NP_001031266.1	Gene:	PTP1 / 843516	AraportID:	AT1G71860	Length:	340	Species:	Arabidopsis thaliana

Alignment Length:	345	Identity:	100/345 - (28%)
Similarity:	155/345 - (44%)	Gaps:	23/345 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly   905 SGRITSLSKENEGRPPSSRSSTSSWSEEPALTNMDISTGHMVLSYMEDHLRNKGRLQREWEALCR 969
            :|:.:|.:....|......||..|...:.:|::..::..|..|......::|...:..|:..|..
plant     3 TGKTSSAANLFTGSTRFDLSSADSPPSKLSLSSDQLNHCHQALGVFRGKIQNPDSIAHEFTGLQA 67

  Fly   970 YEAEPSA----REAASQPQCAGLNRPGAPLPYDHSRVVLNHLANAEGLDYVNASTI-TDHDPRAP 1029
            ....||.    ...|........||....:|:|.:|:|||...::....|||||.| |.......
plant    68 NRMWPSELLLNSTVAMNSVNVEKNRYSDVVPFDKNRIVLNPCKDSSAKGYVNASLIKTSESESIS 132

  Fly  1030 AYVAAQGPLPSTLAHFWQMIWEQGAVVIVALCRLQENGE-VACARYW-PEEGAEVYHIYEVHLVS 1092
            .::|.|||||.|:..||:|:.:|...:||.|.||.:|.. |.|..|: .|:|...:.  .:.|.:
plant   133 QFIATQGPLPHTMEDFWEMVIQQHCPIIVMLTRLVDNNRTVKCGDYFQDEDGPREFG--NISLTT 195

  Fly  1093 EHIWCDDYLVRSFYLKNLRTSETRT------VTQFHFLSWPHMGVPAQAKALLDFRRKVNKSYRG 1151
            :.|...|   .|..|:||..:...|      |....:..||..|||....|:   |..:.:.|:.
plant   196 KWIKTTD---TSLMLRNLEVNYKETEDQPMSVLHIQYPEWPDHGVPKDTVAV---REILKRLYQV 254

  Fly  1152 RRSC-PIVVHGSAGAGRTGVYILLDLVLERMNKG-AREIDIAATLEHLRDQRAGVVATRQQFEFV 1214
            ..|. ||:||.|||.||||.|..:...::|:..| ...:|:|.|:...|.||.|:|.|..|:.|.
plant   255 PPSLGPIIVHCSAGIGRTGTYCAIHNTIQRILAGDMSALDLAKTVALFRKQRIGMVQTMDQYFFC 319

  Fly  1215 LMAVAEEVHAILKALPANTS 1234
            ..|:.:|:..:.....|.||
plant   320 YNAIVDELEDLTAGTNAGTS 339

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
IA-2	NP_608562.4	Receptor_IA-2	708..795	CDD:288410
		PTPc	960..1220	CDD:214550	86/274 (31%)
		PTPc	995..1220	CDD:238006	79/235 (34%)
PTP1	NP_001031266.1	PTPc_plant_PTP1	117..321	CDD:350496	72/211 (34%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	0	0.000