Protein Alignment IA-2 and Ptpn9

DIOPT Version :10

• Sequence 1: NP_608562.4
• Gene: IA-2 / 33277
• FlyBaseID: FBgn0031294
• Length: 1319
• Species: Drosophila melanogaster
• Sequence 2: NP_062625.2
• Gene: Ptpn9 / 56294
• MGIID: 1928376
• Length: 593
• Species: Mus musculus
• Alignment Length: 320
• Identity: 101/320 - (31%)
• Similarity: 144/320 - (45%)
• Gaps: 49/320 - (15%)

  Fly   933 PAL--TNMDISTGH-MVLSYMEDHL--RNKGRLQREWEALCRYEAEPSAREAASQPQCAGLNRPG 992
            |||  .::.:...| |.:..:.|::  |.|..:..|:|.: |.|........:..|.....||.|
Mouse   271 PALDWDSVHVPGPHAMTIQELVDYVNTRQKRGIYEEYEDI-RRENPVGTFHCSMSPGNLEKNRYG 334

  Fly   993 APLPYDHSRVVLNHLANAEGLDYVNASTITDHDPRAPAYVAAQGPLPSTLAHFWQMIWEQGAVVI 1057
            .....|.:||.|...:.....||:||| ..|...:..||:..||||.:|...||.|:|||..:||
Mouse   335 DVPCLDQTRVKLTKRSGHTQTDYINAS-FMDGYKQKNAYIGTQGPLENTYRDFWLMVWEQKVLVI 398

  Fly  1058 VALCRLQENGEVACARYWPEE---------------GAEVYHIYEVHLVSEHIWCDDYLVRSFYL 1107
            |...|.:|.|...|.:|||.|               |.|..:.|:...:..|
Mouse   399 VMTTRFEEGGRRKCGQYWPLEKDSRIRFGFLTVTNLGVENMNHYKKTTLEIH------------- 450

  Fly  1108 KNLRTSETRTVTQFHFLSWPHMGVPAQAKALLDFRRKV---------NKSYRGRRSC---PIVVH 1160
             |....:.|.||.|.|||||..|||:.|.:|:||.|.|         |...|.:..|   |||||
Mouse   451 -NTEERQKRQVTHFQFLSWPDYGVPSSAASLIDFLRVVRNQQSMAVGNLGARSKGQCPEPPIVVH 514

  Fly  1161 GSAGAGRTGVYILLDLVLERMNKGAREIDIAATLEHLRDQRAGVVATRQQFEFVLMAVAE 1220
            .|||.||||.:..||:.|.::.: ...:::..|:..:|.|||..:.|.:|:.|...|:.|
Mouse   515 CSAGIGRTGTFCSLDICLAQLEE-LGTLNVFQTVSRMRTQRAFSIQTPEQYYFCYKAILE 573

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
IA-2	NP_608562.4	Receptor_IA-2	705..795	CDD:463293
		PTP_DSP_cys	942..1225	CDD:475123	98/309 (32%)
Ptpn9	NP_062625.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..20
		CRAL_TRIO_N	20..66	CDD:215024
		SEC14	90..240	CDD:214706
		PTPc-N9	299..569	CDD:350391	92/286 (32%)