Protein Alignment IA-2 and ptprja

DIOPT Version :10

• Sequence 1: NP_608562.4
• Gene: IA-2 / 33277
• FlyBaseID: FBgn0031294
• Length: 1319
• Species: Drosophila melanogaster
• Sequence 2: NP_001129714.1
• Gene: ptprja / 559679
• ZFINID: ZDB-GENE-030131-8301
• Length: 1650
• Species: Danio rerio
• Alignment Length: 293
• Identity: 97/293 - (33%)
• Similarity: 155/293 - (52%)
• Gaps: 24/293 - (8%)

  Fly   976 AREAASQPQCAGLNRPGAPLPYDHSRVVLNHLANAEGLDYVNASTITDHDPRAPAYVAAQGPLPS 1040
            ::..|..|:....||....||||.|||.|:.|::... ||:||:.:..:..: ..::|||||||.
Zfish  1371 SKTVAVFPENKAKNRYNNVLPYDSSRVKLSVLSSPFD-DYINANYMPGYITK-KEFIAAQGPLPG 1433

  Fly  1041 TLAHFWQMIWEQGAVVIVALCRLQENGEVACARYWPEEGAEVYHIYEVHLVSEHIWCDDYLVRSF 1105
            |:..||::|||:....||.|.:..|.|.|.|..|||.| .:.:....|..:|: |..:|:.:|.|
Zfish  1434 TVNDFWRLIWEKNVHTIVMLTKCNEQGRVKCEEYWPAE-MKTFSNLTVTTISD-IPLEDWTLRDF 1496

  Fly  1106 YLKNLRTSETRTVTQFHFLSWPHMGVPAQAKALLDFRRKVNK---SYRGRRSCPIVVHGSAGAGR 1167
            .:||::|:|.|:|..|||.:||..|||...:.|::||..|.:   .|  .|..|.:||.|||.||
Zfish  1497 EVKNMKTAEIRSVRHFHFTAWPDHGVPETTELLINFRHLVREHMDEY--SRHSPTLVHCSAGVGR 1559

  Fly  1168 TGVYILLDLVLERMNKGAREIDIAATLEHLRDQRAGVVATRQQFEFVLMAVAEEVHAILKALPAN 1232
            ||.:|.:|.::.::.:.. .:|:...:..||..|..:|.|..|:.|:.....:    |:|:...|
Zfish  1560 TGTFIAIDRLIFQIERDG-VVDVYGIIHDLRMHRPLMVQTEDQYVFLNQCAMD----IIKSRTGN 1619

  Fly  1233 TSGEKRELDKDPVVGGGSSSTTTK--EPLKEDK 1263
                    :.|.:....::.|..:  ||||:.|
Zfish  1620 --------NVDLIYQNTAALTIYENFEPLKKGK 1644

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
IA-2	NP_608562.4	Receptor_IA-2	705..795	CDD:463293
		PTP_DSP_cys	942..1225	CDD:475123	87/251 (35%)
ptprja	NP_001129714.1	fn3	102..168	CDD:394996
		FN3	158..676	CDD:442628
		FN3	707..783	CDD:473895
		FN3	968..1031	CDD:214495
		PTP_tm	1157..1279	CDD:465889
		R-PTPc-J	1384..1611	CDD:350463	85/233 (36%)