Protein Alignment IA-2 and ptpn4a

DIOPT Version :10

• Sequence 1: NP_608562.4
• Gene: IA-2 / 33277
• FlyBaseID: FBgn0031294
• Length: 1319
• Species: Drosophila melanogaster
• Sequence 2: XP_068079424.1
• Gene: ptpn4a / 368448
• ZFINID: ZDB-GENE-030616-449
• Length: 929
• Species: Danio rerio
• Alignment Length: 308
• Identity: 105/308 - (34%)
• Similarity: 158/308 - (51%)
• Gaps: 27/308 - (8%)

  Fly   932 EPALTNMDISTGHMVLSYMEDHLRNKGRLQREWEALCRYEAEPS-AREAASQPQCAGLNRPGAPL 995
            :|:..:.|.....|:  |:::.| |.|.:..:::.|  |...|. ....|..||....||.....
Zfish   631 DPSHLDQDAWRDSML--YLKEGL-NSGTILAQFDQL--YRKRPGMTMSCAKLPQNISKNRYRDIS 690

  Fly   996 PYDHSRVVLNHLANAEGLDYVNASTITDHDPRAP---AYVAAQGPLPSTLAHFWQMIWEQGAVVI 1057
            |||.:||:|....     ||:||:.|....|...   .|:|.|||||:|.:.||||.||||:.::
Zfish   691 PYDATRVILKGTE-----DYINANYINMEIPACSLINRYIACQGPLPNTCSDFWQMTWEQGSSMV 750

  Fly  1058 VALCRLQENGEVACARYWPE-EGAEVYHIYEVHLVSEHIWCDDYLVRSFYLKNLRTSETRTVTQF 1121
            |.|....|.|.|.|.:|||. .|:..|..:::...:|. ....:|||...|.::.:.|:|.:||.
Zfish   751 VMLTTQVERGRVKCHQYWPNPSGSATYGGFQISCQTEE-GNSAFLVREITLTHIESGESRELTQI 814

  Fly  1122 HFLSWPHMGVPAQAKALLDFRRKVNKSYRGRRSCPIVVHGSAGAGRTGVYILLD--LVLERMNKG 1184
            .:|:||..|||..:...|||...|.....|:.. |:|||.|||.|||||.|.::  :.|...::.
Zfish   815 QYLAWPDHGVPDDSTDFLDFVALVRNKRAGKDE-PVVVHCSAGIGRTGVLITMETAMCLMECSQP 878

  Fly  1185 AREIDIAATLEHLRDQRAGVVATRQQFEFV---LMAVAEEVHAILKAL 1229
            ...::|..|   :|||||.::.|..||:||   ::.|.||  .::|.|
Zfish   879 VFPLEIVRT---MRDQRAMMIQTPSQFKFVCEAILKVYEE--GLVKPL 921

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
IA-2	NP_608562.4	Receptor_IA-2	705..795	CDD:463293
		PTP_DSP_cys	942..1225	CDD:475123	101/292 (35%)
ptpn4a	XP_068079424.1	B41	30..222	CDD:214604
		FERM_C_PTPN4_PTPN3_like	216..310	CDD:270010
		FA	324..365	CDD:462582
		PDZ_PTPN3-4-like	514..603	CDD:467190
		PTPc-N4	704..915	CDD:350449	80/215 (37%)