Protein Alignment IA-2 and C33H5.16

DIOPT Version :10

• Sequence 1: NP_608562.4
• Gene: IA-2 / 33277
• FlyBaseID: FBgn0031294
• Length: 1319
• Species: Drosophila melanogaster
• Sequence 2: NP_501293.3
• Gene: C33H5.16 / 183190
• WormBaseID: WBGene00016382
• Length: 341
• Species: Caenorhabditis elegans
• Alignment Length: 263
• Identity: 70/263 - (26%)
• Similarity: 120/263 - (45%)
• Gaps: 43/263 - (16%)

  Fly   998 DHSRVVLNHLANAEGLDYVNASTITDHDPRAPAYVAAQGPLPSTLAHFWQMIWEQGAVVIVALCR 1062
            |::||.|.|.....  ||::|:.::. ...|..::.||.||.:|.|.||.|..::....|..||.
 Worm    88 DNNRVKLAHPPWPH--DYIHANFVST-PANAKRFICAQAPLDNTCADFWYMCLQERVEAIFMLCN 149

  Fly  1063 LQENGEVACARYW--PEEGAEVYH--------IYEVHLVSEHIWCDDYLVRSFYL-------KNL 1110
            |.|.|...|:.|:  .|:...|:|        .||.....:.:.....:|:...|       :.|
 Worm   150 LMEKGAKKCSEYYATKEKPELVFHEKDQKITVKYEASGTVKFVKPTKAVVKETVLIIEGPGGQVL 214

  Fly  1111 RTSETRTVTQFHFLSWPHMGVPAQAKALLDFRRKVNKSYRGRRSCPIVVHGSAGAGRTGVYILLD 1175
            :|      |.:|::.||..|||....::::...|. :..:|    ||.||.|||.||||..::::
 Worm   215 KT------THYHWIDWPDRGVPPADLSIIELLIKA-RPLKG----PIAVHCSAGIGRTGSVVMIE 268

  Fly  1176 LVLERMNKGAREIDIAATLEHLRDQRAGVVATRQQFEFVLMAVAEEVHAILKALPANTSGEKREL 1240
            .:.|::..|.:..:....|:.:|:||...:.|..|:.|        ||.::    .|...||:..
 Worm   269 YMCEQLLNGNQIEETDKILQKIREQRNNSIQTDHQYLF--------VHQVM----MNFFLEKKLF 321

  Fly  1241 DKD 1243
            |::
 Worm   322 DEE 324

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
IA-2	NP_608562.4	Receptor_IA-2	705..795	CDD:463293
		PTP_DSP_cys	942..1225	CDD:475123	66/243 (27%)
C33H5.16	NP_501293.3	Y_phosphatase	76..313	CDD:459674	66/250 (26%)