Protein Alignment IA-2 and ptrg-1

DIOPT Version :10

• Sequence 1: NP_608562.4
• Gene: IA-2 / 33277
• FlyBaseID: FBgn0031294
• Length: 1319
• Species: Drosophila melanogaster
• Sequence 2: NP_001255470.1
• Gene: ptrg-1 / 177898
• WormBaseID: WBGene00010558
• Length: 1159
• Species: Caenorhabditis elegans
• Alignment Length: 299
• Identity: 94/299 - (31%)
• Similarity: 156/299 - (52%)
• Gaps: 39/299 - (13%)

  Fly   949 YMEDHLRNKG-RLQREWEALCRYEAEPSAREA-------ASQPQCAGLNRPGAPLPYDHSRVVLN 1005
            |:||..||.. :.:.:::.|   |::.|..::       :|..:.:..||.......:.:|:.||
 Worm   631 YVEDLNRNDSLKFKTQFQIL---ESQTSGIDSVDSGESNSSSDENSQKNRYNNIGAIEATRIRLN 692

  Fly  1006 HLANAEGLDYVNASTITDHDPRAPAYVAAQGPLPSTLAHFWQMIWEQGAVVIVALCRLQENGEVA 1070
               :..|.||:||:.:...:.| .||:|.|.|||||.:.||.|||::.:.:||.:..:.|:|:..
 Worm   693 ---SPTGNDYINANYVDSCNER-NAYIATQAPLPSTFSDFWSMIWQERSNIIVCITNMVEDGKRK 753

  Fly  1071 CARYWP--EEGAEVYHIYEVHLVSE----HIWCDDYLVRSFYLKNLRTSET-----RTVTQFHFL 1124
            |.:|||  ::..:.:..|:|.||||    |.        |..:.:|:.::.     |.|.|.||:
 Worm   754 CDQYWPSQQDSPQTFGNYQVTLVSESTNAHF--------SHRILDLKIAKAVPAVERKVHQLHFM 810

  Fly  1125 SWPHMGVPAQAKALLDFRRKVNKSYRGRRSCPIVVHGSAGAGRTGVYILLDLVLERMNKGAREID 1189
            .||..|||:....||.|   |:.:.....:.|:|||.|||.||:|.|||:| .:.|.....|.::
 Worm   811 GWPDHGVPSSVFPLLSF---VHYTSDIHSTGPVVVHCSAGVGRSGSYILVD-SMRRHLISFRRLN 871

  Fly  1190 IAATLEHLRDQRAGVVATRQQFEFVLMAVAEEV-HAILK 1227
            :...|.|:|.|||.:|.|.:|:.|...|:.:.: |.|.:
 Worm   872 VQGHLTHMRRQRAKLVQTLEQYIFCHEAIRQLIRHGITR 910

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
IA-2	NP_608562.4	Receptor_IA-2	705..795	CDD:463293
		PTP_DSP_cys	942..1225	CDD:475123	93/295 (32%)
ptrg-1	NP_001255470.1	FN3	40..490	CDD:442628
		FN3	140..232	CDD:238020
		PTPc	642..900	CDD:214550	86/276 (31%)
		PTP_DSP_cys	959..1148	CDD:475123