Protein Alignment IA-2 and Y48G9A.9

DIOPT Version :10

• Sequence 1: NP_608562.4
• Gene: IA-2 / 33277
• FlyBaseID: FBgn0031294
• Length: 1319
• Species: Drosophila melanogaster
• Sequence 2: NP_001022893.1
• Gene: Y48G9A.9 / 175343
• WormBaseID: WBGene00021702
• Length: 361
• Species: Caenorhabditis elegans
• Alignment Length: 355
• Identity: 95/355 - (26%)
• Similarity: 149/355 - (41%)
• Gaps: 45/355 - (12%)

  Fly   906 GRITSLSKENEGRPPSSRSSTSSWSEEPALTNMDISTGHMVLSYMEDHLRNKGRLQREW------ 964
            |||.::|....|.|      ...:.|.|...|......|.:....:||.|........:
 Worm     8 GRIKAVSSVPRGTP------IYQFFEAPDANNNYDENEHKIYKKTDDHHRKYVETLNNFIIATEK 66

  Fly   965 ---EALCRYEAEPSAREAASQ-----PQCAGLNRPGAPLPYDHSRVVLNHLANAEGLDYVNASTI 1021
               |.|.:...:..|::.:|.     .|....||....:..|.:||.|. :..:...||::|:.:
 Worm    67 LGIEGLAKQYRKLDAQQDSSLTFEAFKQNMHKNRYSDVVCRDTTRVKLT-IDKSRYEDYIHANYV 130

  Fly  1022 TDHDPRAPAYVAAQGPLPSTLAHFWQMIWEQGAVVIVALCRLQENGEVACARYWPEEG-AEVYHI 1085
            ..:..| ..::..||||..|:..||:||:::.|..|:.||:..|.|...|..|||..| .|.|..
 Worm   131 KTNYLR-NTFICTQGPLQHTIIDFWRMIFQERAESILMLCKTMEEGRPKCVGYWPSLGVTETYGC 194

  Fly  1086 YEVHLVSEHIWCDDY----LVRSFYLKNLRTSETRT------VTQFHFLSWPHMGVPAQAKALLD 1140
            ..|..:.|.  .|::    |..:|...|:...|...      |....:.:||..|||.: |....
 Worm   195 IRVTNMGES--SDEFEICNLAVTFVPDNVPVDEQPANLKELRVNLIKWPNWPDRGVPDE-KCHTV 256

  Fly  1141 FRRKVNKSYRGRRSCPIVVHGSAGAGRTGVYILLDLVLERMNKGAREIDIAATLEHLRDQRAGVV 1205
            .:|.:.:...|    |.|||.|||.||||..:.|:....::::|.: :|....:..||.|||..:
 Worm   257 PQRLLAQVRHG----PCVVHCSAGIGRTGCVVALEFAYNKLDRGLK-VDFEEIITELRKQRAQCI 316

  Fly  1206 ATRQQFEF---VLMAVAE-EVHAILKALPA 1231
            .|..|:.:   |::|.|. |.....|||.|
 Worm   317 QTEIQYLYIHRVMIAFARGETDVSEKALAA 346

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
IA-2	NP_608562.4	Receptor_IA-2	705..795	CDD:463293
		PTP_DSP_cys	942..1225	CDD:475123	82/311 (26%)
Y48G9A.9	NP_001022893.1	PTPc	71..330	CDD:214550	74/268 (28%)