DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG4341 and bbs4

DIOPT Version :9

Sequence 1:	NP_608558.1	Gene:	CG4341 / 33276	FlyBaseID:	FBgn0028481	Length:	938	Species:	Drosophila melanogaster
Sequence 2:	NP_001070934.2	Gene:	bbs4 / 768303	ZFINID:	ZDB-GENE-060126-2	Length:	528	Species:	Danio rerio

Alignment Length:	496	Identity:	103/496 - (20%)
Similarity:	180/496 - (36%)	Gaps:	130/496 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly   514 LPFLPASNLLFYVGFVVAERLLYLPSVGFCLLVGYGVSKLMSCNQRTRNILLLSFSLLLAAMSLR 578
            ||.|...|.|.::.::..:               |...|.:...|......:..:::.:.|:.:|
Zfish    29 LPILEKRNWLIHLHYIRKD---------------YETCKAIVKEQLHETQGMCEYAVYVQALIMR 78

  Fly   579 TLRRNADWRDEES--LYRSAIAINPPKALGNLGSVLSS---QGRYEEAKQVLQEAIRFRPNMADV 638
                 .:.:.:||  |::|...|||..: .||..|..|   .|:::.|.:|..||.|......::
Zfish    79 -----LEGKIQESLELFQSCAIINPTSS-DNLKQVARSLFLLGKHKAAIEVYNEAARLNQKDWEI 137

  Fly   639 HFNLGI---------------------------------LHQNQQVYPAAVECFQRAIKFRPNLA 670
            ..|||:                                 :|..|.....|::.::.|::|.|...
Zfish   138 SHNLGVCYIYTKDFRSAEEQLNLALQLNKHDLTYMMLGKIHLLQGDTEKAIDVYKSAVEFSPENT 202

  Fly   671 VAYLNLGISFIALGKRQQAIE---------------ILQAGSNLDGAAVRDRTAHDQARSSAYL- 719
            .....||:.::.|||.|:|.|               ||.|||.:......| .|.::.|.:||.
Zfish   203 ELLTTLGLLYMQLGKYQKAFEHLGNALTYDPNNFKAILAAGSMMQTHGDYD-VAMNKYRVAAYAV 266

  Fly   720 --------QLGALYVEQGKLQRALAIYREA--LSSLPGLPQQREILYQRIGDVLGRLQQWDEAER 774
                    .:|..:..:.|...|::..:.|  ||     |...:||| .:|.|...:||:..|..
Zfish   267 PESPPLWNNIGMCFFGKKKYVAAISCLKRANYLS-----PFDWKILY-NLGLVHLTMQQFASAFH 325

  Fly   775 HHRAALELQPNQVAAHLSYGITLARNSSRASEAEMWFKRALKLAPEQASVYHHYAEFLSLQSRHH 839
            ...||:.|:|.....::...:.|. |...|..|...:::|:::......|..::|.||..|.
Zfish   326 FLSAAINLRPRMSELYMLLAVALT-NLDDAENARRSYEQAVQIDESSPLVNLNFAVFLYNQG--- 386

  Fly   840 ESAIYHRRAAELAPNDYTLVVAAATAMRLLDRKVDAEMWYRKAVALRPGDAHAHTNLGAILHL-- 902
                 .::||.|...:             ::|||:.::.........|........||..|..
Zfish   387 -----DKKAALLQYQE-------------MERKVNTQLENSSNTEFDPELVEMAQKLGGALQAGE 433

  Fly   903 ---------LGRTNHAAASYKAALRLQPGDAITLGNLAKLG 934
                     .|:|:..::|.|.:...||     ||....||
Zfish   434 NLYWSKPGKDGKTSQRSSSSKPSGSQQP-----LGTNQALG 469

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4341	NP_608558.1	PMT_2	112..>232	CDD:304453
		DUF1736	275..343	CDD:285594
		TPR_11	602..667	CDD:290150	18/100 (18%)
		TPR_1	602..634	CDD:278916	10/34 (29%)
		TPR repeat	602..630	CDD:276809	9/30 (30%)
		TPR repeat	635..665	CDD:276809	7/62 (11%)
		TPR_11	636..700	CDD:290150	22/111 (20%)
		TPR_1	636..668	CDD:278916	8/64 (13%)
		TPR repeat	670..694	CDD:276809	9/38 (24%)
		TPR_11	714..784	CDD:290150	21/80 (26%)
		TPR repeat	715..743	CDD:276809	6/38 (16%)
		TPR repeat	748..782	CDD:276809	11/33 (33%)
		TPR_11	755..819	CDD:290150	16/63 (25%)
		TPR repeat	787..816	CDD:276809	5/28 (18%)
		TPR_11	821..887	CDD:290150	11/65 (17%)
		TPR repeat	822..850	CDD:276809	6/27 (22%)
		TPR repeat	855..885	CDD:276809	3/29 (10%)
		TPR_11	<874..921	CDD:290150	8/57 (14%)
		TPR repeat	890..918	CDD:276809	7/38 (18%)
bbs4	NP_001070934.2	TPR repeat	68..95	CDD:276809	6/31 (19%)
		TPR_11	100..166	CDD:290150	13/66 (20%)
		TPR repeat	104..129	CDD:276809	8/24 (33%)
		TPR repeat	134..164	CDD:276809	3/29 (10%)
		TPR_11	169..233	CDD:290150	14/63 (22%)
		TPR repeat	169..196	CDD:276809	4/26 (15%)
		TPR repeat	202..229	CDD:276809	8/26 (31%)
		TPR_11	235..301	CDD:290150	16/71 (23%)
		TPR repeat	237..264	CDD:276809	8/27 (30%)
		TPR repeat	270..298	CDD:276809	4/27 (15%)
		PH-like	<272..340	CDD:302622	19/73 (26%)
		TPR_11	272..335	CDD:290150	18/68 (26%)
		TPR repeat	303..333	CDD:276809	10/30 (33%)
		TPR_11	305..369	CDD:290150	17/65 (26%)
		TPR repeat	338..366	CDD:276809	5/28 (18%)
		TPR repeat	372..397	CDD:276809	8/32 (25%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1124
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.900