DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG4341 and Dnaaf4

DIOPT Version :9

Sequence 1:NP_608558.1 Gene:CG4341 / 33276 FlyBaseID:FBgn0028481 Length:938 Species:Drosophila melanogaster
Sequence 2:NP_080590.3 Gene:Dnaaf4 / 67685 MGIID:1914935 Length:420 Species:Mus musculus


Alignment Length:196 Identity:47/196 - (23%)
Similarity:76/196 - (38%) Gaps:39/196 - (19%)


- Green bases have known domain annotations that are detailed below.


  Fly   559 RTRNILLLSFSLLLAAMSLR--TLRRNADWRDEESLYRSAIAINPPKALGNLGSVLSSQGRYEEA 621
            |:...:.:||:..:...:||  .:....:|..:::..|.|::.:.|:...               
Mouse   231 RSAGSIQISFTPRVFPTALRESQVAEEEEWLHKQAEARRAMSTDLPEFFD--------------- 280

  Fly   622 KQVLQEAIRFRPNMADVHFNLGILHQNQQVYPAAVECFQRAIKFRPNLAVAYLNLGISFIALGKR 686
               |:|..| .|:......|.....:|   |.|||:.:..||:....:.:.|||.....:.|...
Mouse   281 ---LKEEER-NPDWLKDKGNKLFATEN---YLAAVDAYNLAIRLNCKIPLLYLNRAACHLKLKNL 338

  Fly   687 QQAIEILQAGSNL------DGAAVRDRTAHDQARSSAYLQLGALYVEQGKLQRALAIYREALSSL 745
            .:|||.......|      |.|..|.: ||.: |.:|:.|| .||||      .|..|..||...
Mouse   339 HKAIEDSSKALELLTPPVADNANARMK-AHVR-RGTAFCQL-ELYVE------GLQDYEAALKID 394

  Fly   746 P 746
            |
Mouse   395 P 395

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG4341NP_608558.1 PMT_2 112..>232 CDD:304453
DUF1736 275..343 CDD:285594
TPR_11 602..667 CDD:290150 13/64 (20%)
TPR_1 602..634 CDD:278916 4/31 (13%)
TPR repeat 602..630 CDD:276809 3/27 (11%)
TPR repeat 635..665 CDD:276809 8/29 (28%)
TPR_11 636..700 CDD:290150 16/69 (23%)
TPR_1 636..668 CDD:278916 8/31 (26%)
TPR repeat 670..694 CDD:276809 7/23 (30%)
TPR_11 714..784 CDD:290150 13/33 (39%)
TPR repeat 715..743 CDD:276809 10/27 (37%)
TPR repeat 748..782 CDD:276809
TPR_11 755..819 CDD:290150
TPR repeat 787..816 CDD:276809
TPR_11 821..887 CDD:290150
TPR repeat 822..850 CDD:276809
TPR repeat 855..885 CDD:276809
TPR_11 <874..921 CDD:290150
TPR repeat 890..918 CDD:276809
Dnaaf4NP_080590.3 Mediates interaction with ESR1 and STUB1. /evidence=ECO:0000250 7..103
p23_DYX1C1_like 10..87 CDD:107226
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 164..212
TPR_11 287..351 CDD:290150 16/66 (24%)
TPR 1 288..321 9/35 (26%)
TPR repeat 288..316 CDD:276809 8/30 (27%)
TPR repeat 321..351 CDD:276809 7/29 (24%)
TPR 2 322..355 8/32 (25%)
TPR_1 322..351 CDD:278916 7/28 (25%)
TPR_12 324..396 CDD:290160 26/81 (32%)
TPR repeat 362..392 CDD:276809 14/38 (37%)
TPR 3 364..397 15/41 (37%)
TPR_1 365..397 CDD:278916 15/40 (38%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E2759_KOG1124
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.900

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