| Sequence 1: | NP_608558.1 | Gene: | Tmtc2 / 33276 | FlyBaseID: | FBgn0028481 | Length: | 938 | Species: | Drosophila melanogaster |
|---|---|---|---|---|---|---|---|---|---|
| Sequence 2: | NP_003105.2 | Gene: | SPAG1 / 6674 | HGNCID: | 11212 | Length: | 926 | Species: | Homo sapiens |
| Alignment Length: | 407 | Identity: | 87/407 - (21%) |
|---|---|---|---|
| Similarity: | 127/407 - (31%) | Gaps: | 147/407 - (36%) |
- Green bases have known domain annotations that are detailed below.
|
Fly 602 PKALGNLGSVLSSQGRYEEAKQVLQEAIR-FRPNMADVHFNLGILHQNQQV-------YPAAVEC 658
Fly 659 FQRAIKFRPNLAVAYLNLGISFIALGKRQQAIEILQAGSNLDGAAVRDRTAHDQARSSAYLQLGA 723
Fly 724 LYVEQ-----------------GKLQRAL-----AIYREALSSLPGLPQQREILYQRIGDVLGRL 766
Fly 767 QQWDEAERHHRAALELQPNQVAAHLSYGITLARNSSRASEAEMWFKRALKLAPEQASVYHHYAEF 831
Fly 832 LS-----LQSRHHESAIYHRRAA--------ELAPNDYTLVVAAATAMRLLDRKVDAEMWYRKAV 883
Fly 884 A-------------------LRPGDAHAHTNLGAILHLLGRTNHAAASYKAALRL---------- 919
Fly 920 -----QPGDAITLGNLA 931 |
| Gene | Sequence | Domain | Region | External ID | Identity |
|---|---|---|---|---|---|
| Tmtc2 | NP_608558.1 | TMTC_DUF1736 | 270..343 | CDD:462468 | |
| TPR | 597..852 | CDD:440225 | 63/292 (22%) | ||
| TPR repeat | 602..630 | CDD:276809 | 8/27 (30%) | ||
| TPR repeat | 635..665 | CDD:276809 | 6/36 (17%) | ||
| TPR repeat | 670..694 | CDD:276809 | 5/23 (22%) | ||
| TPR repeat | 715..743 | CDD:276809 | 9/49 (18%) | ||
| TPR repeat | 748..782 | CDD:276809 | 5/33 (15%) | ||
| TPR | 780..>933 | CDD:440225 | 47/199 (24%) | ||
| TPR repeat | 787..816 | CDD:276809 | 8/28 (29%) | ||
| TPR repeat | 822..850 | CDD:276809 | 10/40 (25%) | ||
| TPR repeat | 855..885 | CDD:276809 | 10/48 (21%) | ||
| TPR repeat | 890..918 | CDD:276809 | 6/27 (22%) | ||
| SPAG1 | NP_003105.2 | 3a0801s09 | 141..>339 | CDD:273380 | |
| TPR 1 | 209..242 | ||||
| TPR repeat | 213..237 | CDD:276809 | |||
| TPR repeat | 242..271 | CDD:276809 | |||
| TPR 2 | 244..275 | ||||
| TPR 3 | 276..309 | ||||
| TPR repeat | 276..304 | CDD:276809 | |||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 318..452 | 2/6 (33%) | |||
| TPR 4 | 445..478 | 9/32 (28%) | |||
| 3a0801s09 | <446..>731 | CDD:273380 | 76/354 (21%) | ||
| TPR repeat | 448..481 | CDD:276809 | 9/32 (28%) | ||
| TPR repeat | 486..516 | CDD:276809 | 6/29 (21%) | ||
| TPR 5 | 487..520 | 6/42 (14%) | |||
| TPR repeat | 521..549 | CDD:276809 | 9/52 (17%) | ||
| TPR 6 | 522..554 | 9/56 (16%) | |||
| TPR 7 | 623..656 | 10/33 (30%) | |||
| TPR repeat | 624..651 | CDD:276809 | 8/27 (30%) | ||
| TPR repeat | 656..686 | CDD:276809 | 10/35 (29%) | ||
| TPR 8 | 657..690 | 11/38 (29%) | |||
| TPR repeat | 691..718 | CDD:276809 | 6/28 (21%) | ||
| TPR 9 | 692..724 | 7/33 (21%) | |||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 758..801 | 4/24 (17%) | |||
| RPAP3_C | 803..894 | CDD:464012 | |||
| Blue background indicates that the domain is not in the aligned region. | |||||