DRSC/TRiP Functional Genomics Resources

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back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment CG4341 and ifit8

DIOPT Version :9

Sequence 1:NP_608558.1 Gene:CG4341 / 33276 FlyBaseID:FBgn0028481 Length:938 Species:Drosophila melanogaster
Sequence 2:NP_001032654.1 Gene:ifit8 / 641567 ZFINID:ZDB-GENE-051127-17 Length:429 Species:Danio rerio


Alignment Length:395 Identity:83/395 - (21%)
Similarity:131/395 - (33%) Gaps:133/395 - (33%)


- Green bases have known domain annotations that are detailed below.


  Fly   639 HFNLGILHQNQQVYPAAVECFQR-AIK--FRPNLAVAYLNLGISFIALGKRQQAIEILQAGSNLD 700
            ||..|:|.::..:....|:..:| .:|  :..||....||    |:|..|..|.... :|..|| 
Zfish    12 HFTWGLLKEDADLNFLEVKIRERLGVKSGYEGNLKQRELN----FLAFIKHLQGFND-EALKNL- 70

  Fly   701 GAAVRDRTAHDQARSSAYLQLGAL---------------YVEQGKLQRALAIYREALSSLPGLPQ 750
               :..:..|.....:..:..|.|               |:|:         ..|.|.:.|....
Zfish    71 ---LLAKEEHPNDDRTVIVTYGNLAWVHSFLSNATEAEAYIEK---------INEILRAFPTPEL 123

  Fly   751 QREIL--------------YQRIGDV-LGRLQ------QWD-------------EAERHHRA--- 778
            .||:|              |.|..:: |..||      :|:             :..::||.   
Zfish   124 HREVLSEKAWSLLKFSKKSYIRAKEIFLEALQKEPDDKEWNTGLAFSLFRLEGLKIGQYHRVRFE 188

  Fly   779 ----------ALELQPNQVAAHLSYGITLARNSSRASEAEMWFKRALKLAPEQASVYHHYAEFLS 833
                      ||:|.|:.....:..|:...:| .:.|||..:..:|||:||...||..|.|:|:.
Zfish   189 ESPAVLQLKKALKLDPDNPMILVYLGLKCYKN-IKNSEAWQYMTQALKMAPHNLSVVLHVAKFMK 252

  Fly   834 LQ--------------------SR-HHESA----------------------IYH-RRAAELAPN 854
            .:                    || |||.|                      ::| .:.|.|.|.
Zfish   253 KEQCYDRALDVLLEMLKKAPDSSRLHHEVANNYRWKAMQIDDIHNPELLGLCVHHLEKGASLNPG 317

  Fly   855 DYTLVVAAATAMRLLDRKVDAEMWYRKAVA---LRPGDAHA-HTNLGAI-LHLLGRTNHAAASYK 914
            .....:..|.....|.:...||..:.:..:   |:|.|..| |...|.. |:.||....|...||
Zfish   318 YVYPQLELALRYAELKQAGKAEQKFTELFSKPDLKPADLQAWHRLYGDFKLYRLGSEKAAVEHYK 382

  Fly   915 AALRL 919
            ..:.|
Zfish   383 QGMML 387

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG4341NP_608558.1 PMT_2 112..>232 CDD:304453
DUF1736 275..343 CDD:285594
TPR_11 602..667 CDD:290150 7/30 (23%)
TPR_1 602..634 CDD:278916
TPR repeat 602..630 CDD:276809
TPR repeat 635..665 CDD:276809 7/28 (25%)
TPR_11 636..700 CDD:290150 17/63 (27%)
TPR_1 636..668 CDD:278916 7/31 (23%)
TPR repeat 670..694 CDD:276809 6/23 (26%)
TPR_11 714..784 CDD:290150 21/131 (16%)
TPR repeat 715..743 CDD:276809 5/42 (12%)
TPR repeat 748..782 CDD:276809 13/80 (16%)
TPR_11 755..819 CDD:290150 21/110 (19%)
TPR repeat 787..816 CDD:276809 6/28 (21%)
TPR_11 821..887 CDD:290150 20/112 (18%)
TPR repeat 822..850 CDD:276809 12/71 (17%)
TPR repeat 855..885 CDD:276809 4/32 (13%)
TPR_11 <874..921 CDD:290150 15/51 (29%)
TPR repeat 890..918 CDD:276809 9/29 (31%)
ifit8NP_001032654.1 TPR_12 50..117 CDD:290160 16/84 (19%)
TPR repeat 206..236 CDD:276809 7/30 (23%)
TPR repeat 241..269 CDD:276809 5/27 (19%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E2759_KOG1124
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
ZFIN 00.000 Not matched by this tool.
21.810

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