DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG4341 and FKBPL

DIOPT Version :9

Sequence 1:NP_608558.1 Gene:CG4341 / 33276 FlyBaseID:FBgn0028481 Length:938 Species:Drosophila melanogaster
Sequence 2:NP_071393.2 Gene:FKBPL / 63943 HGNCID:13949 Length:349 Species:Homo sapiens


Alignment Length:333 Identity:66/333 - (19%)
Similarity:109/333 - (32%) Gaps:82/333 - (24%)


- Green bases have known domain annotations that are detailed below.


  Fly   438 APHLVSSAFRGSRSSSSCSNSTNSSSSSSSSSSSSSSSSSSLSGGFQCSSKDYALE------GMS 496
            :|...|.....::.:..........|..|..|:|....:...|..:.|....:..:      |:.
Human    52 SPDPASQILEHTQGAEKLVAELEGDSHKSHGSTSQMPEALQASDLWYCPDGSFVKKIVIRGHGLD 116

  Fly   497 PANRHACVLIMSLSFLALPFLPASNLLFYVGFVVAERLLYLPSVGFC-LLVGYG----------V 550
            .....:|..:::|.|   ||...                  |..|:. |.:|.|          :
Human   117 KPKLGSCCRVLALGF---PFGSG------------------PPEGWTELTMGVGPWREETWGELI 160

  Fly   551 SKLMS--CNQRTRNILLLSFSLLLAAMSLRTLRRNAD-WR----DEESLYRSAIAINPPKALGNL 608
            .|.:.  |......:.|...|.....::|.:..:..| |.    ::|:|.|...|         .
Human   161 EKCLESMCQGEEAELQLPGHSGPPVRLTLASFTQGRDSWELETSEKEALAREERA---------R 216

  Fly   609 GSVLSSQGRYEEAKQVLQEAIRF--------RPNMADVHFNLG----ILHQNQQVYPAAVECFQR 661
            |:.|...|..|.|.:....|:|.        .|....:|.||.    :|.|.|.   ||..| .|
Human   217 GTELFRAGNPEGAARCYGRALRLLLTLPPPGPPERTVLHANLAACQLLLGQPQL---AAQSC-DR 277

  Fly   662 AIKFRPNLAVAYLNLGISFIALGKRQQAIEILQAGSNLDGAAVRDRTAHDQARSSAYLQLGALYV 726
            .::..|....|....|::..|||..::|.           |.::...|.|....:|..:||.:.:
Human   278 VLEREPGHLKALYRRGVAQAALGNLEKAT-----------ADLKKVLAIDPKNRAAQEELGKVVI 331

  Fly   727 EQGKLQRA 734
             |||.|.|
Human   332 -QGKNQDA 338

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG4341NP_608558.1 PMT_2 112..>232 CDD:304453
DUF1736 275..343 CDD:285594
TPR_11 602..667 CDD:290150 18/76 (24%)
TPR_1 602..634 CDD:278916 7/39 (18%)
TPR repeat 602..630 CDD:276809 6/27 (22%)
TPR repeat 635..665 CDD:276809 10/33 (30%)
TPR_11 636..700 CDD:290150 17/67 (25%)
TPR_1 636..668 CDD:278916 10/35 (29%)
TPR repeat 670..694 CDD:276809 6/23 (26%)
TPR_11 714..784 CDD:290150 8/21 (38%)
TPR repeat 715..743 CDD:276809 8/20 (40%)
TPR repeat 748..782 CDD:276809
TPR_11 755..819 CDD:290150
TPR repeat 787..816 CDD:276809
TPR_11 821..887 CDD:290150
TPR repeat 822..850 CDD:276809
TPR repeat 855..885 CDD:276809
TPR_11 <874..921 CDD:290150
TPR repeat 890..918 CDD:276809
FKBPLNP_071393.2 Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 36..55 1/2 (50%)
TPR_11 187..>348 CDD:330823 43/177 (24%)
TPR 1 210..243 9/41 (22%)
TPR repeat 210..238 CDD:276809 8/36 (22%)
TPR repeat 251..281 CDD:276809 10/33 (30%)
TPR 2 252..285 11/36 (31%)
TPR 3 286..319 9/43 (21%)
TPR repeat 286..314 CDD:276809 7/38 (18%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E2759_KOG1124
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
10.900

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