DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG4341 and spag1a

DIOPT Version :9

Sequence 1:NP_608558.1 Gene:CG4341 / 33276 FlyBaseID:FBgn0028481 Length:938 Species:Drosophila melanogaster
Sequence 2:NP_001082875.2 Gene:spag1a / 564953 ZFINID:ZDB-GENE-030131-9443 Length:386 Species:Danio rerio


Alignment Length:357 Identity:71/357 - (19%)
Similarity:130/357 - (36%) Gaps:110/357 - (30%)


- Green bases have known domain annotations that are detailed below.


  Fly   598 AINPPKA-LGNLGSVLSSQGRYEEAKQVLQEAIRFRPNMADVHFNLGI--------LHQNQQVYP 653
            |:.||.| |.|.|::|...|::.:|.:...:||       |.....||        |:.|:    
Zfish    79 ALPPPLARLKNQGNMLFKNGQFGDALEKYTQAI-------DGCIEAGIDSPEDLCVLYSNR---- 132

  Fly   654 AA--------VECFQ---RAIKFRPNLAVAYLNLGISFIALGKRQQAIEILQAGSNLDGAAVRDR 707
            ||        .:|.|   ||::..|......|...:::.:|.:.::|....:....:|   :..:
Zfish   133 AACFLKDGNSADCIQDCTRALELHPFSLKPLLRRAMAYESLERYRKAYVDYKTVLQID---ISVQ 194

  Fly   708 TAHDQARSSAYLQLGALYVEQGKLQRALAIYREALSSLPGLP----QQR------EILYQRI--- 759
            .|||...     ::..:.:||....     :||.|..:|.:|    |.|      |:|..|.   
Zfish   195 AAHDSVH-----RITKMLIEQDGPD-----WREKLPEIPAVPLSAQQHRKEEPSAELLQARAERA 249

  Fly   760 ------------------GDVLGRLQQWDEAERHHRAALELQPNQVAAHLSYGITLARNSSRASE 806
                              |:.|.:..|:..|...:...|.::||:.|.:.:..:...: ..|.:|
Zfish   250 EQEKARKAEARFTILKQEGNELVKNSQFQGASEKYSECLAIKPNECAIYTNRALCFLK-LERFAE 313

  Fly   807 AEMWFKRALKLAPEQASVYHHYAEFLSLQSRHHESAIYHRRAAELAPNDYTLVVAAATAMRLLDR 871
            |:.....||::.|:                  ::.|.|.|..|.....||   ::|:|.:     
Zfish   314 AKQDCDSALQMEPK------------------NKKAFYRRALAHKGLKDY---LSASTDL----- 352

  Fly   872 KVDAEMWYRKAVALRPGDAHAHTNLGAILHLL 903
                    ::.:.|.|....|...|..:.:||
Zfish   353 --------QEVLQLDPNVQEAEQELEMVTNLL 376

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG4341NP_608558.1 PMT_2 112..>232 CDD:304453
DUF1736 275..343 CDD:285594
TPR_11 602..667 CDD:290150 21/84 (25%)
TPR_1 602..634 CDD:278916 10/32 (31%)
TPR repeat 602..630 CDD:276809 9/28 (32%)
TPR repeat 635..665 CDD:276809 11/48 (23%)
TPR_11 636..700 CDD:290150 15/82 (18%)
TPR_1 636..668 CDD:278916 11/50 (22%)
TPR repeat 670..694 CDD:276809 3/23 (13%)
TPR_11 714..784 CDD:290150 17/100 (17%)
TPR repeat 715..743 CDD:276809 4/27 (15%)
TPR repeat 748..782 CDD:276809 11/64 (17%)
TPR_11 755..819 CDD:290150 15/84 (18%)
TPR repeat 787..816 CDD:276809 5/28 (18%)
TPR_11 821..887 CDD:290150 9/65 (14%)
TPR repeat 822..850 CDD:276809 3/27 (11%)
TPR repeat 855..885 CDD:276809 4/29 (14%)
TPR_11 <874..921 CDD:290150 6/30 (20%)
TPR repeat 890..918 CDD:276809 4/14 (29%)
spag1aNP_001082875.2 TPR_11 87..157 CDD:290150 19/80 (24%)
TPR repeat 87..112 CDD:276809 8/31 (26%)
TPR repeat 125..155 CDD:276809 8/33 (24%)
TPR_11 128..190 CDD:290150 12/65 (18%)
TPR repeat 160..188 CDD:276809 3/27 (11%)
TPR_11 263..326 CDD:290150 13/63 (21%)
TPR repeat 263..289 CDD:276809 4/25 (16%)
TPR repeat 294..324 CDD:276809 6/30 (20%)
TPR_11 297..360 CDD:290150 15/97 (15%)
TPR_1 297..328 CDD:278916 6/49 (12%)
TPR repeat 329..357 CDD:276809 8/43 (19%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E2759_KOG1124
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
ZFIN 00.000 Not matched by this tool.
10.900

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