DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG4341 and ogt.1

DIOPT Version :9

Sequence 1:	NP_608558.1	Gene:	CG4341 / 33276	FlyBaseID:	FBgn0028481	Length:	938	Species:	Drosophila melanogaster
Sequence 2:	NP_001017359.1	Gene:	ogt.1 / 337685	ZFINID:	ZDB-GENE-030131-9631	Length:	1062	Species:	Danio rerio

Alignment Length:	427	Identity:	112/427 - (26%)
Similarity:	182/427 - (42%)	Gaps:	80/427 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly   570 LLLAAMSLRTLRRNADWRDEESLYRSAIAI--NP--PKALGNLGSVLSSQGRYEEAKQVLQEAIR 630
            |||:::..:..|.      :.|.:.|.:||  ||  .:|..|||:|...:|:.:||.:..:.|:|
Zfish    59 LLLSSIHFQCRRL------DRSAHFSTLAIKQNPMLAEAYSNLGNVYKERGQLQEAIEHYRHALR 117

  Fly   631 FRPNMADVHFNL-------GILHQNQQVYPAAVE---------------------------CFQR 661
            .:|:..|.:.||       |.:....|.|.:|::                           |:.:
Zfish   118 LKPDFIDGYINLAAALVAAGDMEGAVQAYVSALQYNPDLYCVRSDLGNLLKALGRLEEAKACYLK 182

  Fly   662 AIKFRPNLAVAYLNLGISFIALGKRQQAIEILQAGSNLD----------GAAVRDRTAHDQARSS 716
            ||:.:||.|||:.|||..|.|.|:...||...:....||          |..:::....|:| .:
Zfish   183 AIETQPNFAVAWSNLGCVFNAQGEIWLAIHHFEKAVTLDPNFLDAYINLGNVLKEARIFDRA-VA 246

  Fly   717 AYLQ--------------LGALYVEQGKLQRALAIYREALSSLPGLPQQREILYQRIGDVLGRLQ 767
            .||:              |..:|.|||.:..|:..||.|:...|..|.    .|..:.:.|....
Zfish   247 GYLRALSLSPNHAVVHGNLACVYYEQGLIDLAIDTYRRAIELQPHFPD----AYCNLANALKEKG 307

  Fly   768 QWDEAERHHRAALELQPNQVAAHLSYGITLARNSSRASEAEMWFKRALKLAPEQASVYHHYAEFL 832
            ...|||..:..||.|.|.. |..|:....:.|......||...:::||::.||.|:.:.:.|..|
Zfish   308 NVSEAEECYNTALRLCPTH-ADSLNNLANIKREQGNIEEAVQLYRKALEVFPEFAAAHSNLASVL 371

  Fly   833 SLQSRHHESAIYHRRAAELAPNDYTLVVAAATAMRLLDRKVDAE---MWYRKAVALRPGDAHAHT 894
            ..|.:..|:.::::.|..::|   |...|.:.....|....|.:   ..|.:|:.:.|..|.||:
Zfish   372 QQQGKLQEALMHYKEAIRISP---TFADAYSNMGNTLKEMQDVQGALQCYTRAIQINPAFADAHS 433

  Fly   895 NLGAILHLLGRTNHAAASYKAALRLQPGDAITLGNLA 931
            ||.:|....|....|.|||:.||:|:|.......|||
Zfish   434 NLASIHKDSGNIPEAIASYRTALKLKPDFPDAYCNLA 470

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4341	NP_608558.1	PMT_2	112..>232	CDD:304453
		DUF1736	275..343	CDD:285594
		TPR_11	602..667	CDD:290150	21/98 (21%)
		TPR_1	602..634	CDD:278916	10/31 (32%)
		TPR repeat	602..630	CDD:276809	9/27 (33%)
		TPR repeat	635..665	CDD:276809	10/63 (16%)
		TPR_11	636..700	CDD:290150	23/97 (24%)
		TPR_1	636..668	CDD:278916	10/65 (15%)
		TPR repeat	670..694	CDD:276809	11/23 (48%)
		TPR_11	714..784	CDD:290150	21/83 (25%)
		TPR repeat	715..743	CDD:276809	11/41 (27%)
		TPR repeat	748..782	CDD:276809	8/33 (24%)
		TPR_11	755..819	CDD:290150	16/63 (25%)
		TPR repeat	787..816	CDD:276809	6/28 (21%)
		TPR_11	821..887	CDD:290150	13/68 (19%)
		TPR repeat	822..850	CDD:276809	6/27 (22%)
		TPR repeat	855..885	CDD:276809	6/32 (19%)
		TPR_11	<874..921	CDD:290150	18/49 (37%)
		TPR repeat	890..918	CDD:276809	12/27 (44%)
ogt.1	NP_001017359.1	TPR	20..285	CDD:223533	59/232 (25%)
		TPR repeat	24..49	CDD:276809
		TPR repeat	57..83	CDD:276809	7/29 (24%)
		TPR_1	89..122	CDD:278916	11/32 (34%)
		TPR repeat	89..117	CDD:276809	9/27 (33%)
		TPR repeat	122..152	CDD:276809	7/29 (24%)
		TPR repeat	157..185	CDD:276809	2/27 (7%)
		TPR_1	163..190	CDD:278916	4/26 (15%)
		TPR_1	191..224	CDD:278916	13/32 (41%)
		TPR repeat	191..219	CDD:276809	11/27 (41%)
		TPR	204..461	CDD:223533	67/265 (25%)
		TPR_17	213..246	CDD:290167	5/33 (15%)
		TPR repeat	226..253	CDD:276809	5/27 (19%)
		TPR repeat	259..287	CDD:276809	9/27 (33%)
		SNAP	276..430	CDD:305195	38/161 (24%)
		TPR repeat	290..322	CDD:276937	9/35 (26%)
		TPR_1	293..326	CDD:278916	10/36 (28%)
		TPR repeat	293..321	CDD:276809	7/31 (23%)
		TPR repeat	323..358	CDD:276937	8/35 (23%)
		TPR repeat	326..356	CDD:276809	7/30 (23%)
		TPR repeat	361..389	CDD:276809	6/27 (22%)
		TPR repeat	362..402	CDD:276937	8/42 (19%)
		TPR repeat	395..423	CDD:276809	5/27 (19%)
		TPR_1	429..462	CDD:278916	15/32 (47%)
		TPR repeat	429..457	CDD:276809	12/27 (44%)
		Glyco_transf_41	556..1038	CDD:290556
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910