DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG4341 and Spag1

DIOPT Version :9

Sequence 1:NP_608558.1 Gene:CG4341 / 33276 FlyBaseID:FBgn0028481 Length:938 Species:Drosophila melanogaster
Sequence 2:NP_001012116.1 Gene:Spag1 / 315033 RGDID:1310702 Length:893 Species:Rattus norvegicus


Alignment Length:303 Identity:64/303 - (21%)
Similarity:108/303 - (35%) Gaps:88/303 - (29%)


- Green bases have known domain annotations that are detailed below.


  Fly   598 AINPPKALGNLGSVLSSQGRYEEAKQVLQEAI-RFRPNMADVHFNLGILHQNQQVYPAAV----- 656
            |.:.|..|.:.|:.|...|::.||......|| :..|..::....|.||:.|:    ||.     
  Rat   425 AADSPGDLKSRGNELFRGGQFAEAAVQYSGAIAQLEPTGSENADELSILYSNR----AACYLKEG 485

  Fly   657 ---ECFQ---RAIKFRP-------NLAVAYLNLG------ISFIALGKRQQAIEILQAGSN---- 698
               .|.|   ||::.:|       ..|:||..|.      :.:|.:.|....|::.....|    
  Rat   486 NCRGCIQDCDRALELQPFAVKPLLRRAMAYETLEQYRSAYVDYITVLKIDCRIQLASDSVNRITR 550

  Fly   699 ----LDGAAVRDR----------------------------------TAHDQARSSAYLQLGALY 725
                |||...|:|                                  |..|:....|..:.|...
  Rat   551 ILTELDGPKWRERLPPIPAVPASEPLRVWHPAAETPDQDPCPNSCTPTITDEKMFQALKEEGNQL 615

  Fly   726 VEQGKLQRALAIYREAL---SSLPGLPQQREILYQRIGDVLGRLQQWDEAERHHRAALELQPNQV 787
            |:....:.|::.|.|.|   |....:...|.:.|.::|       |::||:.....||::....|
  Rat   616 VKDKNYKDAISKYNECLKINSKACAIYTNRALCYLKLG-------QFEEAKLDCDKALQIDSKNV 673

  Fly   788 AAHLSYGITLAR---NSSRASEAEMWFKRALKLAPEQASVYHH 827
            .|  ||.:.||:   .:.|...|:.  .:.:.|:|:.:....|
  Rat   674 KA--SYRLELAQKGLENCRERVADP--SQVVLLSPDSSEAARH 712

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG4341NP_608558.1 PMT_2 112..>232 CDD:304453
DUF1736 275..343 CDD:285594
TPR_11 602..667 CDD:290150 20/76 (26%)
TPR_1 602..634 CDD:278916 9/32 (28%)
TPR repeat 602..630 CDD:276809 9/28 (32%)
TPR repeat 635..665 CDD:276809 10/40 (25%)
TPR_11 636..700 CDD:290150 19/95 (20%)
TPR_1 636..668 CDD:278916 11/49 (22%)
TPR repeat 670..694 CDD:276809 7/29 (24%)
TPR_11 714..784 CDD:290150 16/72 (22%)
TPR repeat 715..743 CDD:276809 7/30 (23%)
TPR repeat 748..782 CDD:276809 8/33 (24%)
TPR_11 755..819 CDD:290150 16/66 (24%)
TPR repeat 787..816 CDD:276809 8/31 (26%)
TPR_11 821..887 CDD:290150 1/7 (14%)
TPR repeat 822..850 CDD:276809 1/6 (17%)
TPR repeat 855..885 CDD:276809
TPR_11 <874..921 CDD:290150
TPR repeat 890..918 CDD:276809
Spag1NP_001012116.1 Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 112..155
3a0801s09 141..>303 CDD:273380
TPR 1 213..246
TPR repeat 217..241 CDD:276809
TPR repeat 246..275 CDD:276809
TPR 2 247..279
TPR 3 280..313
TPR repeat 280..308 CDD:276809
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 324..344
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 349..368
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 373..437 3/11 (27%)
TPR 4 429..463 10/33 (30%)
3a0801s09 <432..>569 CDD:273380 33/140 (24%)
TPR repeat 432..458 CDD:276809 8/25 (32%)
TPR repeat 466..500 CDD:276809 10/37 (27%)
TPR 5 471..504 10/36 (28%)
TPR repeat 505..533 CDD:276809 5/27 (19%)
TPR 6 506..538 6/31 (19%)
3a0801s09 569..>695 CDD:273380 25/134 (19%)
TPR 7 605..638 8/32 (25%)
TPR repeat 606..633 CDD:276809 6/26 (23%)
TPR repeat 638..668 CDD:276809 8/36 (22%)
TPR 8 639..672 8/39 (21%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 704..756 2/9 (22%)
RPAP3_C 769..858 CDD:404718
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E2759_KOG1124
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.900

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