DRSC/TRiP Functional Genomics Resources

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back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment CG4341 and Bbs4

DIOPT Version :9

Sequence 1:NP_608558.1 Gene:CG4341 / 33276 FlyBaseID:FBgn0028481 Length:938 Species:Drosophila melanogaster
Sequence 2:XP_038937022.1 Gene:Bbs4 / 300754 RGDID:1309134 Length:529 Species:Rattus norvegicus


Alignment Length:450 Identity:97/450 - (21%)
Similarity:160/450 - (35%) Gaps:95/450 - (21%)


- Green bases have known domain annotations that are detailed below.


  Fly   503 CVLIMSLSFLALPFLPASNLLFYVGFVVAERLLYLPSVGFCLLVGYGVSKLMSCNQRTRNILLLS 567
            |.|...|.||.|..|..........|.:.|:|.:|..: :.:...|...|.:...|......|..
  Rat    13 CPLPGKLRFLHLLNLKNPGQKKAPEFPIVEKLNWLIHL-YYIRKDYEACKAVIKEQLQETQGLCE 76

  Fly   568 FSLLLAAMSLRTLRRNADWRDEESL-YRSAIAINPPKALGNLGSVLSS---QGRYEEAKQVLQEA 628
            :::.:.|:..| |..|.    :||| .....|:..|:...||..|..|   .|:::.|.:|..||
  Rat    77 YAIYVQALIFR-LEGNI----QESLELFQTCAVLSPQCADNLKQVARSLFLLGKHKAATEVYNEA 136

  Fly   629 IRFRPNMADVHFNLGI---------------------------------LHQNQQVYPAAVECFQ 660
            .:......::..|||:                                 :|..|.....|:|.::
  Rat   137 AKLNQKDWEICHNLGVCYTYLKQFSKAQDQLHSALQLNKHDLTYIMLGKIHLLQGDLDKAIEIYK 201

  Fly   661 RAIKFRPNLAVAYLNLGISFIALGKRQQAIEILQAGSNLDGAAVRDRTAHDQARSSAYLQLGALY 725
            :|::|.|........||:.::.||..|:|.|.|       |.|:    .:|.|...|.|..|::.
  Rat   202 KAVEFSPENTELLTTLGLLYLQLGVYQKAFEHL-------GNAL----TYDPANYKAILAAGSMM 255

  Fly   726 VEQGKLQRALAIYREALSSLPGLPQQREILYQRIGDVLGRLQQWDEAERHHRAALELQPNQVAAH 790
            ...|....||..||....::|..|.    |:..||...       ..::.:.||:..        
  Rat   256 QTHGDFDVALTKYRVVACAIPESPP----LWNNIGMCF-------FGKKKYVAAISC-------- 301

  Fly   791 LSYGITLARNSSRASEAEMWFKRALKLAPEQASVYHHYAEFLSLQSRHHESAIYHRRAA-ELAPN 854
                                .|||..|||....:.::.. .:.|..:.:.||.:...|| ...|.
  Rat   302 --------------------LKRANYLAPFDWKILYNLG-LVHLTMQQYASAFHFLSAAINFQPK 345

  Fly   855 DYTLVVAAATAMRLLDRKVDAEMWYRKAVALRPGDAHAHTNLGAILHLLGRTNHAAASYK 914
            ...|.:..|.|:..|:...:|:..|.:||.|...:...:.|...:|:..|....|.|.|:
  Rat   346 MGELYMLLAVALTNLEDIENAKRAYVEAVRLDKCNPLVNLNYAVLLYNQGEKKGALAQYQ 405

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG4341NP_608558.1 PMT_2 112..>232 CDD:304453
DUF1736 275..343 CDD:285594
TPR_11 602..667 CDD:290150 19/100 (19%)
TPR_1 602..634 CDD:278916 10/34 (29%)
TPR repeat 602..630 CDD:276809 10/30 (33%)
TPR repeat 635..665 CDD:276809 8/62 (13%)
TPR_11 636..700 CDD:290150 18/96 (19%)
TPR_1 636..668 CDD:278916 9/64 (14%)
TPR repeat 670..694 CDD:276809 7/23 (30%)
TPR_11 714..784 CDD:290150 15/69 (22%)
TPR repeat 715..743 CDD:276809 8/27 (30%)
TPR repeat 748..782 CDD:276809 6/33 (18%)
TPR_11 755..819 CDD:290150 9/63 (14%)
TPR repeat 787..816 CDD:276809 3/28 (11%)
TPR_11 821..887 CDD:290150 15/66 (23%)
TPR repeat 822..850 CDD:276809 5/28 (18%)
TPR repeat 855..885 CDD:276809 8/29 (28%)
TPR_11 <874..921 CDD:290150 11/40 (28%)
TPR repeat 890..918 CDD:276809 6/24 (25%)
Bbs4XP_038937022.1 PEP_TPR_lipo <31..442 CDD:274350 90/431 (21%)
TPR repeat 77..104 CDD:276809 7/31 (23%)
TPR repeat 110..138 CDD:276809 9/27 (33%)
TPR repeat 143..173 CDD:276809 3/29 (10%)
TPR repeat 178..205 CDD:276809 5/26 (19%)
TPR repeat 211..238 CDD:276809 9/33 (27%)
TPR repeat 245..273 CDD:276809 8/27 (30%)
TPR repeat 279..307 CDD:276809 9/66 (14%)
TPR repeat 312..342 CDD:276809 5/30 (17%)
TPR repeat 347..375 CDD:276809 7/27 (26%)
TPR repeat 381..406 CDD:276809 6/24 (25%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E2759_KOG1124
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.900

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