DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG4341 and Ifit2

DIOPT Version :9

Sequence 1:	NP_608558.1	Gene:	CG4341 / 33276	FlyBaseID:	FBgn0028481	Length:	938	Species:	Drosophila melanogaster
Sequence 2:	NP_001019924.1	Gene:	Ifit2 / 294091	RGDID:	1307804	Length:	464	Species:	Rattus norvegicus

Alignment Length:	268	Identity:	44/268 - (16%)
Similarity:	95/268 - (35%)	Gaps:	71/268 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly   585 DW---RDEESLYRSAIAINPPKALGNLGSVLSSQGRYE-EAKQVLQEAIRFRPNMADVHFNLGIL 645
            ||   .|.......||:::|......:...:..:..:| .||::::||::..|:..|........
  Rat   187 DWPASNDYIDSLEQAISLSPDNTYVKVLLAMKLEEVHENRAKELVEEALKKDPSAIDTMLGAAKF 251

  Fly   646 HQNQQVYPAAVECFQRAIKFRPNLAVAYLNLGISFIALGKRQQAIEILQAGSNLDGAAVRDRTAH 710
            :........|::..::|::..||.|..:..||..:     |.:.:.||..
  Rat   252 YVKVHDTDRAIQLLKKALESMPNNAYVHYYLGCCY-----RSKVLHILNT--------------- 296

  Fly   711 DQARSSAYLQLGALYVEQGKLQRALAIYREALSSLPGLPQQREILYQRIGDVLG---RLQQWDEA 772
            ::..|:            |..::..|:.:.||:.|......:|::......:.|   ..:|::||
  Rat   297 EETTSN------------GNREKLEALIQPALNHLRKAEDIKEMIENSCSHLAGLYVTTKQYEEA 349

  Fly   773 ERHHRAALELQPNQVAAHLSYGITLARNSSRASEAEMWFKRALKLAPEQASVYHHYAEFLSLQSR 837
            :.:.:..                               |.:.|:..|:|. ::..|..|...:.:
  Rat   350 DYYFQKE-------------------------------FNKDLRPLPKQL-LHLRYGNFQFYERK 382

  Fly   838 HHESAIYH 845
            ..:.||||
  Rat   383 CEDRAIYH 390

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4341	NP_608558.1	PMT_2	112..>232	CDD:304453
		DUF1736	275..343	CDD:285594
		TPR_11	602..667	CDD:290150	9/65 (14%)
		TPR_1	602..634	CDD:278916	5/32 (16%)
		TPR repeat	602..630	CDD:276809	5/28 (18%)
		TPR repeat	635..665	CDD:276809	3/29 (10%)
		TPR_11	636..700	CDD:290150	11/63 (17%)
		TPR_1	636..668	CDD:278916	3/31 (10%)
		TPR repeat	670..694	CDD:276809	5/23 (22%)
		TPR_11	714..784	CDD:290150	11/72 (15%)
		TPR repeat	715..743	CDD:276809	4/27 (15%)
		TPR repeat	748..782	CDD:276809	5/36 (14%)
		TPR_11	755..819	CDD:290150	6/66 (9%)
		TPR repeat	787..816	CDD:276809	1/28 (4%)
		TPR_11	821..887	CDD:290150	7/25 (28%)
		TPR repeat	822..850	CDD:276809	6/24 (25%)
		TPR repeat	855..885	CDD:276809
		TPR_11	<874..921	CDD:290150
		TPR repeat	890..918	CDD:276809
Ifit2	NP_001019924.1	TPR_12	51..126	CDD:290160
		TPR repeat	96..122	CDD:276809
		TPR repeat	127..167	CDD:276809
		TPR repeat	242..270	CDD:276809	3/27 (11%)
		TPR repeat	275..325	CDD:276809	12/81 (15%)
		TPR repeat	330..355	CDD:276809	4/24 (17%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1124
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810