Protein Alignment Tmtc2 and Kdm6b

DIOPT Version :10

• Sequence 1: NP_608558.1
• Gene: Tmtc2 / 33276
• FlyBaseID: FBgn0028481
• Length: 938
• Species: Drosophila melanogaster
• Sequence 2: XP_030101676.1
• Gene: Kdm6b / 216850
• MGIID: 2448492
• Length: 1642
• Species: Mus musculus
• Alignment Length: 204
• Identity: 52/204 - (25%)
• Similarity: 77/204 - (37%)
• Gaps: 54/204 - (26%)

  Fly   339 YSVLVGVAWGSCRQLLSGSKEVTHCGVSSTFPQYHIQKVASRKSRSKRKRLANNTKYQAFEAAYH 403
            ::.|.|.|||..|:   ||                    |..:.:.:|..:.::..|.|...:.|
Mouse   284 WNTLHGDAWGPERK---GS--------------------APPERQEQRHSMPHSYPYPAPAYSAH 325

  Fly   404 QQQQEALPCRDCNNNNSSGYVYEGSSPVAQAPAQAP---HLVSSAFRGSRSSSSCSNSTNSS--- 462
            ......:|    |.....|....|:......||..|   .|..|..:.||..||.|.:.:::
Mouse   326 PPSHRLVP----NTPLGPGPRPPGAESHGCLPATRPPGSDLRESRVQRSRMDSSVSPAASTACVP 386

  Fly   463 ----------SSSSSSSSSSSSSSSSLSG-----GFQCSS--KDYALEGMSPANRHACVLIMSLS 510
                      .:||||||||||:::.|.|     |...:.  ::.||| :||   |...|..|..
Mouse   387 YAPSRPPGLPGTSSSSSSSSSSNNTGLRGVEPSPGIPGADHYQNPALE-ISP---HQARLGPSAH 447

  Fly   511 FLALPFLPA 519
            ....|||.|
Mouse   448 SSRKPFLTA 456

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tmtc2	NP_608558.1	TMTC_DUF1736	270..343	CDD:462468	0/3 (0%)
		TPR	597..852	CDD:440225
		TPR repeat	602..630	CDD:276809
		TPR repeat	635..665	CDD:276809
		TPR repeat	670..694	CDD:276809
		TPR repeat	715..743	CDD:276809
		TPR repeat	748..782	CDD:276809
		TPR	780..>933	CDD:440225
		TPR repeat	787..816	CDD:276809
		TPR repeat	822..850	CDD:276809
		TPR repeat	855..885	CDD:276809
		TPR repeat	890..918	CDD:276809
Kdm6b	XP_030101676.1	BepA	<90..154	CDD:443813
		TPR repeat	106..136	CDD:276809
		JmjC	1342..1406	CDD:214721
		JmjC	1376..1484	CDD:396791