DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG4341 and Ttc24

DIOPT Version :9

Sequence 1:NP_608558.1 Gene:CG4341 / 33276 FlyBaseID:FBgn0028481 Length:938 Species:Drosophila melanogaster
Sequence 2:NP_766114.1 Gene:Ttc24 / 214191 MGIID:2443841 Length:334 Species:Mus musculus


Alignment Length:312 Identity:72/312 - (23%)
Similarity:107/312 - (34%) Gaps:111/312 - (35%)


- Green bases have known domain annotations that are detailed below.


  Fly   612 LSSQGRYEEAKQVLQEAIRFRPN--MADVHFNLGILHQNQQVYPAAVECFQRAIKF--RPN-LAV 671
            ||...|..|..:.|.:|.|....  :...:.:||:.:...|::|.|||.|.:|:..  :|: .|.
Mouse     9 LSDVLRALEESRKLADADRSTDQGLLGPFYNDLGMGYFQLQLFPLAVEAFLQALPLCRQPSEQAT 73

  Fly   672 AYLNLGISFIALGKRQQAIEILQAGSNLDGAAVRDRTAHDQARS------------------SAY 718
            ...|||::...||...:|.|..|..::|.| :|..|  .:|.||                  .:|
Mouse    74 VLQNLGMTHNVLGNYWEAQEFHQKAASLHG-SVGQR--WEQGRSFSGLAFSLSQLGDHRAAWDSY 135

  Fly   719 LQ--------------------LGALYVEQGKLQRALAIYREALSSLPGLPQQ-REILYQRIGDV 762
            |.                    |||.....|:..:||..|:|||:.....|.. ||.|..::.|.
Mouse   136 LHALQAAQDTGDVKGQWQACEGLGAAAARLGQHDQALKYYKEALALCQHEPSSVRERLVAKLADA 200

  Fly   763 L-------------------GRLQ---------------------QWD-EAER--HHRAALE--- 781
            :                   |:||                     ||: ||..  |.:..:|   
Mouse   201 MRTFVAQEKIAQARFLPSAPGKLQTSRKAKTSARVQSSAEDAQESQWEGEASEGGHEKKEMEGLV 265

  Fly   782 -----LQP---NQVAAHL----------SYGITLARNSSRASEAEMWFKRAL 815
                 |.|   |:...||          .|...:|....|.|.:..|.|.||
Mouse   266 NTATVLGPQRQNRATTHLPSGGPSPSGEEYPFIIAPKKLRVSRSSTWAKEAL 317

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG4341NP_608558.1 PMT_2 112..>232 CDD:304453
DUF1736 275..343 CDD:285594
TPR_11 602..667 CDD:290150 16/58 (28%)
TPR_1 602..634 CDD:278916 7/21 (33%)
TPR repeat 602..630 CDD:276809 6/17 (35%)
TPR repeat 635..665 CDD:276809 9/29 (31%)
TPR_11 636..700 CDD:290150 19/66 (29%)
TPR_1 636..668 CDD:278916 9/33 (27%)
TPR repeat 670..694 CDD:276809 8/23 (35%)
TPR_11 714..784 CDD:290150 29/159 (18%)
TPR repeat 715..743 CDD:276809 12/65 (18%)
TPR repeat 748..782 CDD:276809 14/85 (16%)
TPR_11 755..819 CDD:290150 24/125 (19%)
TPR repeat 787..816 CDD:276809 10/39 (26%)
TPR_11 821..887 CDD:290150
TPR repeat 822..850 CDD:276809
TPR repeat 855..885 CDD:276809
TPR_11 <874..921 CDD:290150
TPR repeat 890..918 CDD:276809
Ttc24NP_766114.1 TPR 1 35..68 9/32 (28%)
TPR repeat 38..66 CDD:276809 9/27 (33%)
TPR_12 68..144 CDD:290160 19/78 (24%)
TPR 2 72..105 11/33 (33%)
TPR repeat 72..100 CDD:276809 9/27 (33%)
TPR repeat 111..141 CDD:276809 5/29 (17%)
TPR 3 112..145 4/32 (13%)
TPR_12 113..183 CDD:290160 14/69 (20%)
TPR 4 152..185 10/32 (31%)
TPR_1 152..184 CDD:278916 10/31 (32%)
TPR repeat 152..180 CDD:276809 9/27 (33%)
TPR_12 158..214 CDD:290160 15/55 (27%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 220..258 8/37 (22%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E2759_KOG1124
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.900

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