DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG4341 and TOMM34

DIOPT Version :9

Sequence 1:NP_608558.1 Gene:CG4341 / 33276 FlyBaseID:FBgn0028481 Length:938 Species:Drosophila melanogaster
Sequence 2:NP_006800.2 Gene:TOMM34 / 10953 HGNCID:15746 Length:309 Species:Homo sapiens


Alignment Length:331 Identity:73/331 - (22%)
Similarity:109/331 - (32%) Gaps:109/331 - (32%)


- Green bases have known domain annotations that are detailed below.


  Fly   582 RNADWRDEESLYRSAIAINPPKALGNLGSVLSSQGRYE-EAKQVLQEAIRFRPNMADVHFNLGIL 645
            ||..:.:..:||..|:            .||.:||..: |.:.||..      |.|..|...|..
Human    21 RNGQYAEASALYGRAL------------RVLQAQGSSDPEEESVLYS------NRAACHLKDGNC 67

  Fly   646 HQNQQVYPAAVECFQ---RAIKFRPNLAVAYLNLGISFIALGKRQQAI----EILQAGSNLDGAA 703
            .          :|.:   .|:...|......|....::.||.|...|.    .:||...|:..| 
Human    68 R----------DCIKDCTSALALVPFSIKPLLRRASAYEALEKYPMAYVDYKTVLQIDDNVTSA- 121

  Fly   704 VRDRTAHDQARSSAYLQLGALYVEQ-GKLQRAL-----AIYREALSSLPGLPQQREILYQRIGDV 762
                                  ||. .::.|||     ..:|..|.|:|.:|...:         
Human   122 ----------------------VEGINRMTRALMDSLGPEWRLKLPSIPLVPVSAQ--------- 155

  Fly   763 LGRLQQWDE--AERHHRAALELQPNQVAAHLSYGITLARNS-SRASEAEMWFKRALKLAPEQAS- 823
                ::|:.  :|.|         .::|...|...|..:|. ..|.:.|.  .|.||   |:.: 
Human   156 ----KRWNSLPSENH---------KEMAKSKSKETTATKNRVPSAGDVEK--ARVLK---EEGNE 202

  Fly   824 ---------VYHHYAEFLSLQSRHHESAIYHRRA-AELAPNDYTLVVAAATAMRLLDRKVDAEMW 878
                     ....|:|  ||...:.|||.|..|| ..|....||..|...|....||.| :.:.:
Human   203 LVKKGNHKKAIEKYSE--SLLCSNLESATYSNRALCYLVLKQYTEAVKDCTEALKLDGK-NVKAF 264

  Fly   879 YRKAVA 884
            ||:|.|
Human   265 YRRAQA 270

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG4341NP_608558.1 PMT_2 112..>232 CDD:304453
DUF1736 275..343 CDD:285594
TPR_11 602..667 CDD:290150 13/68 (19%)
TPR_1 602..634 CDD:278916 7/32 (22%)
TPR repeat 602..630 CDD:276809 7/28 (25%)
TPR repeat 635..665 CDD:276809 5/32 (16%)
TPR_11 636..700 CDD:290150 14/70 (20%)
TPR_1 636..668 CDD:278916 5/34 (15%)
TPR repeat 670..694 CDD:276809 5/27 (19%)
TPR_11 714..784 CDD:290150 13/77 (17%)
TPR repeat 715..743 CDD:276809 6/33 (18%)
TPR repeat 748..782 CDD:276809 4/35 (11%)
TPR_11 755..819 CDD:290150 12/66 (18%)
TPR repeat 787..816 CDD:276809 7/29 (24%)
TPR_11 821..887 CDD:290150 22/75 (29%)
TPR repeat 822..850 CDD:276809 10/38 (26%)
TPR repeat 855..885 CDD:276809 11/30 (37%)
TPR_11 <874..921 CDD:290150 4/11 (36%)
TPR repeat 890..918 CDD:276809
TOMM34NP_006800.2 TPR 1 9..42 7/32 (22%)
TPR repeat 9..37 CDD:276809 5/27 (19%)
PLN03088 <12..>294 CDD:330826 73/331 (22%)
TPR repeat 50..80 CDD:276809 8/45 (18%)
TPR 2 51..84 9/48 (19%)
TPR repeat 85..113 CDD:276809 5/27 (19%)
TPR 3 86..118 7/31 (23%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 161..189 7/36 (19%)
TPR 4 193..226 8/37 (22%)
TPR repeat 193..221 CDD:276809 7/32 (22%)
TPR repeat 226..256 CDD:276809 11/29 (38%)
TPR 5 227..260 13/33 (39%)
TPR repeat 261..289 CDD:276809 4/10 (40%)
TPR 6 262..294 4/9 (44%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E2759_KOG1124
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
10.900

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