DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG4341 and ifit5

DIOPT Version :9

Sequence 1:	NP_608558.1	Gene:	CG4341 / 33276	FlyBaseID:	FBgn0028481	Length:	938	Species:	Drosophila melanogaster
Sequence 2:	NP_001135660.1	Gene:	ifit5 / 100216220	XenbaseID:	XB-GENE-5842099	Length:	473	Species:	Xenopus tropicalis

Alignment Length:	333	Identity:	68/333 - (20%)
Similarity:	122/333 - (36%)	Gaps:	81/333 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly   618 YEEAKQVLQEAIRFRPNMADVHFNLGILHQNQQVYPAAVEC--------------------FQRA 662
            ||.||...:||::..|:  |..:|.|:         |.|.|                    .:||
Frog   153 YERAKGCFEEAVKGNPD--DPEWNTGL---------ATVVCRLEEFRGRNCPAFKSVSFQLLERA 206

  Fly   663 IKFRPNLAVAYLNLGISFIALGKRQQAIEILQAGSNLDGAAVRDRTAHDQARSSAYL--QLGALY 725
            :|..|..:|..:.|.:....|.::::|::.:             :.|.:......|:  .:...|
Frog   207 VKLNPKDSVIKVLLALKLQELKRQEEAMKHI-------------KDALELTPDLPYVLRYVAKFY 258

  Fly   726 VEQGKLQRALAIYREALSSLP---------GLPQQREILY-QRIGDVLGRLQQWDE-------AE 773
            ...||.:..:.:.::|:|..|         ||..::.|:. :|.|....|.|...|       |.
Frog   259 RRAGKFEETIRVLKKAVSITPNSGFLHHQLGLCYRQMIIQRKRTGKANYRGQDTQEIKDLTEKAI 323

  Fly   774 RHHRAALELQPNQVAAHLSYGITLARNSSRASEAEMWFKRALKL--APEQASVYHH--YAEFLSL 834
            .|...|||::...:.||........| |::..:||..:|:|.:|  .||......|  |.:||..
Frog   324 FHFEMALEMKKTFLHAHFDLADMYVR-SNQYQKAEETYKKATELITTPEHEKQQAHLQYGKFLEN 387

  Fly   835 QSRHHESAIYHRRAAELAPNDYTLVVAAATAMRLLDRKVDAEMWYRKAVALRPGDAHAHTNLGAI 899
            ..:..:.|:...:.....|:..|             .:.:.||..|:....|.......|:..|:
Frog   388 SKKSEDEAVEQYKEGLRIPDQNT-------------HRQECEMCLRRIANQRLARNSRDTSALAL 439

  Fly   900 LHLLGRTN 907
            |..:.:.|
Frog   440 LGFISKEN 447

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4341	NP_608558.1	PMT_2	112..>232	CDD:304453
		DUF1736	275..343	CDD:285594
		TPR_11	602..667	CDD:290150	16/68 (24%)
		TPR_1	602..634	CDD:278916	6/15 (40%)
		TPR repeat	602..630	CDD:276809	6/11 (55%)
		TPR repeat	635..665	CDD:276809	8/49 (16%)
		TPR_11	636..700	CDD:290150	14/83 (17%)
		TPR_1	636..668	CDD:278916	9/51 (18%)
		TPR repeat	670..694	CDD:276809	4/23 (17%)
		TPR_11	714..784	CDD:290150	20/88 (23%)
		TPR repeat	715..743	CDD:276809	5/29 (17%)
		TPR repeat	748..782	CDD:276809	11/41 (27%)
		TPR_11	755..819	CDD:290150	19/73 (26%)
		TPR repeat	787..816	CDD:276809	8/28 (29%)
		TPR_11	821..887	CDD:290150	10/67 (15%)
		TPR repeat	822..850	CDD:276809	5/29 (17%)
		TPR repeat	855..885	CDD:276809	4/29 (14%)
		TPR_11	<874..921	CDD:290150	8/34 (24%)
		TPR repeat	890..918	CDD:276809	4/18 (22%)
ifit5	NP_001135660.1	PEP_TPR_lipo	<144..>405	CDD:274350	58/276 (21%)
		TPR repeat	219..242	CDD:276809	4/35 (11%)
		TPR repeat	248..276	CDD:276809	5/27 (19%)
		TPR repeat	281..332	CDD:276809	12/50 (24%)
		TPR repeat	337..365	CDD:276809	8/28 (29%)
		TPR repeat	375..404	CDD:276809	5/28 (18%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910