Protein Alignment GluRIIC and Ir75b

DIOPT Version :9

• Sequence 1: NP_608557.4
• Gene: GluRIIC / 33275
• FlyBaseID: FBgn0046113
• Length: 940
• Species: Drosophila melanogaster
• Sequence 2: NP_001137966.2
• Gene: Ir75b / 8673994
• FlyBaseID: FBgn0261402
• Length: 605
• Species: Drosophila melanogaster
• Alignment Length: 722
• Identity: 128/722 - (17%)
• Similarity: 245/722 - (33%)
• Gaps: 235/722 - (32%)

  Fly   180 QLREVHNDVVRVRKFHKDDDF---RVMWKSIRGERRVVLD--CEPNMLVELLNSSTEFGLTGQYN 239
            |.:.:|:|:      ..:|||   .::      :..|.||  |:.:..|..:.|:..| .:.:|:
  Fly    43 QFQPLHSDI------QLNDDFLNHNIL------KLGVFLDINCDKSGTVLDMASAKRF-FSHRYH 94

  Fly   240 HIFL---TNLETYTDHLEELAADNETFAVNITAARLLVNPDPPPYSLPYGYVTQRDNIVYESSDP 301
            .:..   .|......|.:|              |::.|:.|                :.|.:.||
  Fly    95 WLIYDRSMNFSVLESHFKE--------------AQIFVDAD----------------VTYVTHDP 129

  Fly   302 --PRTLIHDLIHDALQLFAQSWRNASFFYPDRMVVPRITCDFAASGGRT-WAMGRYLARLMKGTS 363
              ...|::|:.:...||..:.               .||.|......:| ..:.|||:.|...::
  Fly   130 FSKNFLLYDVYNKGRQLGGEL---------------NITADREIFCNKTNCRVERYLSELYTRSA 179

  Fly   364 GVNNTNFRTSILQFDEDGQRITFNIEVYDPLDGIGIAIWDPRGQITQLNVDVKAQKKMIYRVATR 428
            ..:..:|....::.......:..|:.:.:        |:|......::.:|..|          |
  Fly   180 LQHRKSFTGLTMRATAVVTALPLNVSIKE--------IFDFMNSKYRIQLDTYA----------R 226

  Fly   429 IGPPYFSYNETARELNLTGNALYQGYAVDLIDAIARHVGFEYVFVPVADQQYGKLDKETKQWN-- 491
            :|   :...:..|               |::|.     .|:|:|              ..:|:
  Fly   227 LG---YQARQPLR---------------DMLDC-----KFKYIF--------------RDRWSDG 254

  Fly   492 ----GIIGEIINNDAHMGICDLTITQARKTAVDFTVPFMQLGV--SILAYKSPH-VEKTLDA--Y 547
                |:||::|.:.|.:.|.....:..|..   |..|..:..|  .|..:::|. |...|.|  :
  Fly   255 NATGGMIGDLILDKADLAIAPFIYSFDRAL---FLQPITKFSVFREICMFRNPRSVSAGLSATEF 316

  Fly   548 LAPFGGEVWI---WILISVFVMTFLKTIVARISKMDWENPHPCNRDPEVLENQWRIHNTGWLTVA 609
            |.||.|.||:   .:|:....:.::..|:.|                   ..||:         .
  Fly   317 LQPFSGGVWLTFALLLLLAGCLLWVTFILER-------------------RKQWK---------P 353

  Fly   610 SIMT-------AGCD----ILPRSPQVRMFEATWWIFAIIIANSYTANLAAFLTSSKMEGSIANL 663
            |::|       |||.    :.|||...||......:.:.::.|.||:.:.:.|....::.:|..|
  Fly   354 SLLTSCLLSFGAGCIQGAWLTPRSMGGRMAFFALMVTSYLMYNYYTSIVVSKLLGQPIKSNIRTL 418

  Fly   664 KDLSAQKKVKFGTIYGGSTYNLLADSN------ETVYRLAFNLMNNDDPSA---YTKDNL----- 714
            :.                    |||||      .|||...: :..:::|..   |.|..|
  Fly   419 QQ--------------------LADSNLDVGIEPTVYTRIY-VETSEEPDVRDLYRKKVLGSKRS 462

  Fly   715 ---------EGVDRVRKNRGDYMFLMETTTLEYHRE-----QNCDLRSVGEKFGEKHYAIAVPFG 765
                     .||..||...|........|..|:.|:     |.|:|..:..: ...|....:...
  Fly   463 PDKIWIPTEAGVLSVRDQEGFVYITGVATGYEFVRKHFLAHQICELNEIPLR-DASHTHTVLAKR 526

  Fly   766 AEYRSNLSVAILKLSERGELYDLKQKWWKNPNASCFEEPDPDATPDMTFEELRGIFYTLYAGILI 830
            :.|...:.::.|::.|.| ::...::.|......|::.   :.|..:..|....:|..|...|::
  Fly   527 SPYAELIKLSELRMLETG-VHFKHERSWMETKLHCYQH---NHTVAVGLEYAAPLFIILLGAIIL 587

  Fly   831 AF-LIGI 836
            .. ::|:
  Fly   588 CMGILGL 594

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
GluRIIC	NP_608557.4	PBP1_iGluR_Kainate	26..404	CDD:107377	38/234 (16%)
		Periplasmic_Binding_Protein_Type_1	<279..363	CDD:299141	15/86 (17%)
		PBP2_iGluR_Kainate	423..794	CDD:270432	79/423 (19%)
		Lig_chan	554..828	CDD:278489	57/315 (18%)
Ir75b	NP_001137966.2	Periplasmic_Binding_Protein_Type_2	253..553	CDD:304360	70/353 (20%)
		Lig_chan	343..585	CDD:278489	54/295 (18%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45462593
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	1.840