Protein Alignment GluRIIC and GLR1.3

DIOPT Version :10

• Sequence 1: NP_608557.4
• Gene: GluRIIC / 33275
• FlyBaseID: FBgn0046113
• Length: 940
• Species: Drosophila melanogaster
• Sequence 2: NP_199652.1
• Gene: GLR1.3 / 834896
• AraportID: AT5G48410
• Length: 860
• Species: Arabidopsis thaliana
• Alignment Length: 952
• Identity: 190/952 - (19%)
• Similarity: 344/952 - (36%)
• Gaps: 249/952 - (26%)

  Fly    29 AFFYDDELELEKEFMTVVN-AINGPESEQTMRFYPLIKRLKPEDGSVTMQEHACDLIDNGVAAIF 92
            ::||    .:..::.|.|: ::.....|..:.....:..||.|                ||.||.
plant    67 SYFY----AIHNDYKTRVSVSLRNSHGEPLLALASAVDLLKTE----------------GVEAII 111

  Fly    93 GPSSKAASDIVALVCNSTGIPHIEFDISDEGIQAEKPNH--QMTLNLYPAQAILSKAYADIVQNF 155
            |.:|...:.::..:.....:|.|..| |...:...|..|  |.|.:    ....:|.....:..|
plant   112 GGNSLLEAKLLGELGEKARVPMISLD-SPFSLSLSKYTHLIQATHD----STSEAKGITSFINVF 171

  Fly   156 GWRKFTIVY-DADDARAAARLQDLLQLREVHNDVVRVRK-----FHKDDDF---RVMWKSIRGER 211
            .|....:|| |.||.|.:.:    |.:...|.:.|||:.     ....:||   |:......|..
plant   172 DWNSVALVYEDHDDWRESMQ----LLVEHFHENGVRVQSKVGFTVSSSEDFVMGRLQQLKDLGTT 232

  Fly   212 RVVLDCEPNMLVELLNSSTEFG---------LTGQYNHIFLTNLETYTDHLEELAADNETFAVNI 267
            ..|:.....:...|...:...|         ||.:..:.|..|::.:|....|.....:::.
plant   233 VFVVHLSEVIATHLFPCARRLGLMGDGFVWILTAKTMNSFHENIDDFTKQAMEGVVGFKSYI--- 294

  Fly   268 TAARLLVNPDPPPYSLPYGYVTQRDNIVYESSDPPRTLI-----HDLIHDALQLFAQSWRNASFF 327
                      |....|....:..|.::..|.::..|..|     ||:.. ||...|:..|
plant   295 ----------PMSIELQNFTLRWRKSLPVEEAELTRLSISGIWAHDIAF-ALARAAEVIR----- 343

  Fly   328 YPDRMVVPRITCDFAASGGRTWAMG----------RYLARLMKGTSGVNNTNFRTSILQFDEDGQ 382
                  :|.:|........:|...|          :.|:...:..:.:.::..|...|..:....
plant   344 ------MPNVTSTLLEEITKTRFNGLSGDFQLNDKKLLSNKFEIINMIGSSERRVGFLNSNGSFS 402

  Fly   383 RITFNIEVYDPLDGIGIAIW------DPRGQITQLNVDVKAQKKMIYRVATRIGPPYFSYNETAR 441
            ........::.|:.|   ||      .|:|  |.|   :.:.:|.:..:.|       |.|...|
plant   403 NRRHLSSTHNKLETI---IWPGGSAQSPKG--TSL---IDSDRKKLRVLVT-------SSNRFPR 452

  Fly   442 ELN-----LTGNALYQGYAVDLIDAIARHVGFEYVFVP---------VADQQYGKLDKETKQWNG 492
            .:.     :|...:.:|:.:::..|......:|..::|         :|...:.:.||
plant   453 LMKVETDPVTNELIVEGFCIEVFRASISPFNYEVEYIPWLNGSNYDNLAYALHSQKDK------- 510

  Fly   493 IIGEIINNDAHMGICDLTITQARKTAVDFTVPFMQLGVSILAYKSPHVEKTLDAYLAPFGGEVWI 557
                   .||.:|  |:|||..|.|.||||:||.::|:.|:|.|    |:::..:..|...::||
plant   511 -------YDAAVG--DITITSNRSTYVDFTLPFTEMGLGIVAVK----ERSMWVFFQPLTPDLWI 562

  Fly   558 WILISVFVMTFLKTIVARISKMDWENPHPCNRDPEVLENQW--RIHNTGWLTVASIMTAGCDILP 620
               .|.|.......||..|.:.:       |::   .:..|  :|....|...::::.|..:.|.
plant   563 ---TSAFFFVLTGVIVWLIERAE-------NKE---FQGSWPQQIGVVLWFGFSTLVYAHREKLK 614

  Fly   621 RSPQVRMFEATWWIFAIIIAN-SYTANLAAFLTSSKMEGSIANLKDLSAQKKVKFGTIYGGSTYN 684
            .:  :..|..|.|:||::|.. ||||.|.:.:|                .::::|
plant   615 HN--LSRFVVTVWVFAVLILTASYTATLTSMMT----------------VQQIRF---------- 651

  Fly   685 LLADSNET-VYRLAFNLMNNDDPSAYTKDNLEGVDRVRKN-RGDYMFLMETTTLEYHREQNCDLR 747
               :|||. |..|:.:|:.|   .|.|..:|..:..:..| ..||...:...|:.:..::...|:
plant   652 ---NSNEDYVGHLSGSLIAN---VALTSSSLRAMRSLGLNSAADYAQALLNKTVSFVVDELPYLK 710

  Fly   748 SV-GEK----FGEKHYAIAVPFGAEYRS------NLSVAILKLSERGELYDLKQKWWKN--PNAS 799
            .| ||.    |..|..:....||..::.      |:|..|.||....:|.:::::|:.|  |..:
plant   711 VVLGENPTHFFMVKTQSTTNGFGFMFQKGFELVPNVSREISKLRTSEKLNEMEKRWFDNQLPYTT 775

  Fly   800 CFEEPDPDATPDMTFEELRGIFYTLYAGILIAFLIGITEFL-------VYVQQVALEERLTFKDA 857
                  .|.:..:|....||:|  :..|:..||.:.:...|       :.|..:.|.:||..
plant   776 ------DDTSNPITLYRFRGLF--IIIGVSFAFALAVLVILCLRDKWEILVDNLDLSQRLRH--- 829

  Fly   858 FKKEIRFVLCVWNNRKPIVAGTPISSVRTTPRRSLDKSLDRT 899
            |:  |.||                .|:.|:|   ||..:..|
plant   830 FR--IHFV----------------RSIHTSP---LDDPIGET 850

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
GluRIIC	NP_608557.4	Periplasmic_Binding_Protein_type1	26..409	CDD:471960	74/421 (18%)
		PBP2_iGluR_Kainate	423..794	CDD:270432	88/400 (22%)
		Lig_chan	554..827	CDD:459656	62/290 (21%)
GLR1.3	NP_199652.1	PBP1_GABAb_receptor_plant	43..405	CDD:380645	68/391 (17%)
		GluR_Plant	438..767	CDD:270404	88/402 (22%)