Protein Alignment GluRIIC and GLR2.1

DIOPT Version :10

• Sequence 1: NP_608557.4
• Gene: GluRIIC / 33275
• FlyBaseID: FBgn0046113
• Length: 940
• Species: Drosophila melanogaster
• Sequence 2: NP_198062.2
• Gene: GLR2.1 / 832768
• AraportID: AT5G27100
• Length: 901
• Species: Arabidopsis thaliana
• Alignment Length: 897
• Identity: 190/897 - (21%)
• Similarity: 344/897 - (38%)
• Gaps: 184/897 - (20%)

  Fly    31 FYDDELELEKEFMTVVNAINGPESEQTMRFYPLIKRLKPEDGSVTMQEHACDLIDN-GVAAIFGP 94
            ||....|.:...:|.|                    :..::..||....|.|||.| .|.||.||
plant    59 FYSSHPETQTRLVTTV--------------------VDSKNDVVTAAAAALDLITNKEVKAILGP 103

  Fly    95 SSKAASDIVALVCNSTGIPHIEFDISDEGIQAEKPNHQMTLNLYPAQAILSKAYADIVQNFGWRK 159
            .:...:..:..:...:.:|.:.:..:...:.:.:..:........:..:  .|..:|::.||||:
plant   104 WTSMQAQFMIEMGQKSQVPIVTYSATSPSLASIRSQYFFRATYDDSSQV--HAIKEIIKLFGWRE 166

  Fly   160 FTIVYDADDARAAA---RLQDLLQ---LREVHNDVVRVRKFHKDDDFRV-MWKSIRGERRVVLDC 217
            ...|| .||.....   ||.|:||   :|..:..|:....  .||:..| :.:.:....||.:
plant   167 VAPVY-VDDTFGEGIMPRLTDVLQEINVRIPYRTVISPNA--TDDEISVELLRMMTLPTRVFV-- 226

  Fly   218 EPNMLVELLNS-----STEFGLTGQYNHIFLTNLETYTDHLEELAADNETFAVNITAARLLVNPD 277
              ..|||||.|     :||.||..|.....|||  |.||.|..:   ||| .:......|.|..
plant   227 --VHLVELLASRFFAKATEIGLMKQGYVWILTN--TITDVLSIM---NET-EIETMQGVLGVKT- 282

  Fly   278 PPPYSLPYGYVTQRDNIV-YESSDPPRTLIHDL------IHD-----ALQLFAQSWRNASFFYPD 330
                     ||.:...:. :.|....|..|.||      .:|     ||.:......|.:|.
plant   283 ---------YVPRSKELENFRSRWTKRFPISDLNVYGLWAYDATTALALAIEEAGTSNLTFV--- 335

  Fly   331 RMVVPRITCDFAASGGRTWAMGRYLARLMKGTSGVN-----------NTNFRTSILQF----DED 380
            :|...|...:....|     :.:|..:|::..|.|.           |...:.|:.:.    .:.
plant   336 KMDAKRNVSELQGLG-----VSQYGPKLLQTLSRVRFQGLAGDFQFINGELQPSVFEIVNVNGQG 395

  Fly   381 GQRITFNIEVY--------DPLDGIGIAIWDPR-------GQITQL--NVDVKAQKKMIYRVATR 428
            |:.|.|.::.|        .|......:.|..|       |..|.:  ..::....|.:     :
plant   396 GRTIGFWMKEYGLFKNVDQKPASKTTFSSWQDRLRPIIWPGDTTSVPKGWEIPTNGKRL-----Q 455

  Fly   429 IGPPYFSYNETAREL------NLTGNALYQGYAVDLIDAIARHVGFE--YVFVPVADQQYGKLDK 485
            ||.|   .|.|.::.      .:|.:.::.|:::|..:|:.:.:.::  |.|:|..|..|
plant   456 IGVP---VNNTFQQFVKATRDPITNSTIFSGFSIDYFEAVIQAIPYDISYDFIPFQDGGY----- 512

  Fly   486 ETKQWNGIIGEIINNDAHMGICDLTITQARKTAVDFTVPFMQLGVSILAYKSPHVEKTLDAYLAP 550
                 :.::.::........:.|.||:..|...|||::|:...||.::......|.::...:|.|
plant   513 -----DALVYQVYLGKYDAVVADTTISSNRSMYVDFSLPYTPSGVGLVVPVKDSVRRSSTIFLMP 572

  Fly   551 FGGEVWIWILISVFVMTFLKTIVARISKMDWENPHPCNRDPEVLENQWRIHNTGWLTVASIMTAG 615
            ....:|:..|:|.|::..:..::......|::.|           .|:::....|.:.:.::.|
plant   573 LTLALWLISLLSFFIIGLVVWVLEHRVNPDFDGP-----------GQYQLSTIFWFSFSIMVFA- 625

  Fly   616 CDILPR----SPQVRMFEATWWIFAIIIANSYTANLAAFLTSSKMEGSIANLKDLSAQKKVKFGT 676
                ||    |...|:....|:...:::..||||:||:.||:..:..::.|:..|.|:     |.
plant   626 ----PRERVLSFWARVVVIIWYFLVLVLTQSYTASLASLLTTQHLHPTVTNINSLLAK-----GE 681

  Fly   677 IYGGSTYNLLADSNETVYRLAFNLMNNDDP----SAYTKDNLEGVDRVRKNRGDYMFLMETTTLE 737
            ..|..:..:|....::.:..| :|::...|    :..:|...||        |....|||...:.
plant   682 SVGYQSSFILGRLRDSGFSEA-SLVSYGSPEHCDALLSKGQAEG--------GVSAVLMEVPYVR 737

  Fly   738 YHREQNCD-LRSVGEKFGEKHYAIAVPFGAEYRSNLSVAILKLSERGELYDLKQKWWKNPNASCF 801
            ....|.|: .:.|...|.........|.|:...:::|.||||:.|..:...|:..|:|..:.||
plant   738 IFLGQYCNKYKMVQTPFKVDGLGFVFPIGSPLVADISRAILKVEESNKANQLENAWFKPIDESC- 801

  Fly   802 EEPD----PDATPDMTFEELRGIFYTLYAGILIAFLIGITEFLVYVQQVALE 849
              ||    ||..|.::|.:|.  |.:.:...|:|.::.....|.:|.|...|
plant   802 --PDPLTNPDPNPSVSFRQLG--FDSFWVLFLVAAIVCTMALLKFVYQFLKE 849

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
GluRIIC	NP_608557.4	Periplasmic_Binding_Protein_type1	26..409	CDD:471960	92/432 (21%)
		PBP2_iGluR_Kainate	423..794	CDD:270432	79/387 (20%)
		Lig_chan	554..827	CDD:459656	63/285 (22%)
GLR2.1	NP_198062.2	PBP1_GABAb_receptor_plant	33..411	CDD:380645	88/404 (22%)
		GluR_Plant	452..794	CDD:270404	79/389 (20%)
		Lig_chan	574..833	CDD:459656	65/293 (22%)