Protein Alignment GluRIIC and GLR2.5

DIOPT Version :10

• Sequence 1: NP_608557.4
• Gene: GluRIIC / 33275
• FlyBaseID: FBgn0046113
• Length: 940
• Species: Drosophila melanogaster
• Sequence 2: NP_001332219.1
• Gene: GLR2.5 / 830991
• AraportID: AT5G11210
• Length: 918
• Species: Arabidopsis thaliana
• Alignment Length: 972
• Identity: 187/972 - (19%)
• Similarity: 343/972 - (35%)
• Gaps: 250/972 - (25%)

  Fly     1 MWQRILLLGCMWSAFFMCRSRGQ------QINIGAFFYDD----ELELE------KEFMTVVN-- 47
            :|..|.|:       |:..|.|:      |:.:|.....:    :|.|.      .||....|
plant    14 LWLLIFLV-------FLVLSLGKSQKEALQVKVGIVLGSNVTLADLSLRAINMSLSEFYNTHNGF 71

  Fly    48 ----AINGPESEQTM------RFYPLIKRLKPEDGSVTMQEHACDLIDNGVAAIFGPSSKAASDI 102
                .:|..:|:||:      ..| |||:.:                   |.||.||.:...:..
plant    72 KTRIVLNVRDSKQTVVGAAASALY-LIKKRE-------------------VVAIIGPGTSMQAPF 116

  Fly   103 VALVCNSTGIPHIEFDISDEGIQAEKPNHQMTLNLYPAQAILSKAYADIVQNFGWRKFTIVYDAD 167
            :..:.|.:.:|.|.|..:...:.:.:..:.:......:..:  :|.:.|:::|.||:...:| .|
plant   117 LINLGNQSKVPIISFSATSPLLDSLRSPYFIRATHDDSSQV--QAISAIIESFRWREVVPIY-VD 178

  Fly   168 DARAAARLQDLLQLREVHNDVVRVR---KFHKDDD------FRVMWKSIR----------GERRV 213
            :......|.:|:...:..|..:|.|   ..|..||      :::|....|          |.|..
plant   179 NEFGEGILPNLVDAFQEINVRIRYRSAISLHYSDDQIKKELYKLMTMPTRVFIVHMLPDLGSRLF 243

  Fly   214 VLDCEPNML------------VELLNSSTEFGLTGQYNHIFLTNLETYTD------HL------- 253
            .:..|.:||            .:|::...|..|...:.   :..::||..      ||
plant   244 SIAKEIDMLSKGYVWIVTNGIADLMSIMGESSLVNMHG---VLGVKTYFAKSKELLHLEARWQKR 305

  Fly   254 ---EEL------AADNET-FAVNITAARLLVNPDPPPYSLPYGYV---TQRDNIVYESSDPPRTL 305
               |||      |.|..| .|:::...|.:        ::.:...   |.||:|..:..:....|
plant   306 FGGEELNNFACWAYDAATALAMSVEEIRHV--------NMSFNTTKEDTSRDDIGTDLDELGVAL 362

  Fly   306 IHDLIHDALQLFAQSWRNASFFYPDRMVVPRITCDFAASGGRTWAMGRYLARLMKGTSGVNNTNF 370
            ....:.|||.                      |..|....||        .:|..|.  :..|.|
plant   363 SGPKLLDALS----------------------TVSFKGVAGR--------FQLKNGK--LEATTF 395

  Fly   371 RTSILQFDEDGQR-------------------ITFNIEVYDPLDGIGIAIWDPRGQITQLNVDVK 416
            :  |:..:|.|:|                   ::.:.....|:...|..|:.|:|.....|.
plant   396 K--IINIEESGERTVGFWKSKVGLVKSLRVDKVSHSSRRLRPIIWPGDTIFVPKGWEFPTNA--- 455

  Fly   417 AQKKMIYRVATRIGPPYFSYNETARELNLTGNALYQGYAVDLIDAIARH----VGFEYVFVPVAD 477
              ||:  |:|......:.::.|..::.| |......|:.:|:.:.:...    |.:||:.....|
plant   456 --KKL--RIAVPKKDGFNNFVEVTKDEN-TNVPTVTGFCIDVFNTVMSQMPYAVSYEYIPFDTPD 515

  Fly   478 -QQYGKLDKETKQWNGIIGEIINNDAHMGICDLTITQARKTAVDFTVPFMQLGVSILAYKSPHVE 541
             :..|..|:..  :|..:||.   |..:|  |.||...|...|||.:|:.:.|:..|.......|
plant   516 GKPRGSYDEMV--YNVFLGEF---DGAVG--DTTILANRSHYVDFALPYSETGIVFLVPVKDGKE 573

  Fly   542 KTLDAYLAPFGGEVWIWILISVFVMTFLKTIVARISKMDWENPHPCN---RDPEVLENQWRIHNT 603
            |....:|.|...|:|:     |...:||     .|..|.|...:..:   |:..:::   :|.:.
plant   574 KGEWVFLKPLTKELWL-----VTAASFL-----YIGIMVWIFEYQADEEFREQMIID---KISSV 625

  Fly   604 GWLTVASIMTAGCDILPRSPQ----VRMFEATWWIFAIIIANSYTANLAAFLTSSKMEGSIANLK 664
            .:.:.:::..|     .|.|.    .|:....|....:|:..||||.|.:.||..::..::.::.
plant   626 FYFSFSTLFFA-----HRRPSESFFTRVLVVVWCFVLLILTQSYTATLTSMLTVQELRPTVRHMD 685

  Fly   665 DLSAQKKVKFGTIYGGSTYNLLADSNETVYRLAFNLMNNDDPSAYTKDNLEGVDRV----RKNRG 725
            || .:..|..|...|..|:..|..            |..|:....|.::.|.:..:    ..|.|
plant   686 DL-RKSGVNIGYQTGSFTFERLKQ------------MRFDESRLKTYNSPEEMRELFLHKSSNGG 737

  Fly   726 DYMFLMETTTLEYHREQNCDLRSVGE-KFGEKHYAIAVPFGAEYRSNLSVAILKLSERGELYDLK 789
            ......|...::....:.|...|:.| .|....:..|.|.|:...|::|..||.::|...:..::
plant   738 IDAAFDEVAYIKLFMAKYCSEYSIIEPTFKADGFGFAFPLGSPLVSDISRQILNITEGDAMKAIE 802

  Fly   790 QKWWKNPNASCFEEPDPDATPDMTFEELRGIFYTLYAGILIAFLIGITEFLVYVQQVALEER 851
            .||:.. ...|.:....|:...:.......:|       ||.|::.:...|:.:.....:||
plant   803 NKWFLG-EKHCLDSTTSDSPIQLDHHSFEALF-------LIVFVVSVILLLLMLASRGYQER 856

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
GluRIIC	NP_608557.4	Periplasmic_Binding_Protein_type1	26..409	CDD:471960	85/480 (18%)
		PBP2_iGluR_Kainate	423..794	CDD:270432	83/387 (21%)
		Lig_chan	554..827	CDD:459656	54/284 (19%)
GLR2.5	NP_001332219.1	PBP1_GABAb_receptor_plant	38..421	CDD:380645	80/450 (18%)
		GluR_Plant	456..806	CDD:270404	84/390 (22%)
		Lig_chan	584..838	CDD:459656	56/292 (19%)