Protein Alignment GluRIIC and GLR2.6

DIOPT Version :10

• Sequence 1: NP_608557.4
• Gene: GluRIIC / 33275
• FlyBaseID: FBgn0046113
• Length: 940
• Species: Drosophila melanogaster
• Sequence 2: NP_001330285.1
• Gene: GLR2.6 / 830988
• AraportID: AT5G11180
• Length: 967
• Species: Arabidopsis thaliana
• Alignment Length: 829
• Identity: 165/829 - (19%)
• Similarity: 301/829 - (36%)
• Gaps: 158/829 - (19%)

  Fly    88 VAAIFGPSSKAASDIVALVCNSTGIPHIEFDISDEGIQA------EKPNHQMTLNLYPAQAILSK 146
            |.||.||.:...:..:..:.|.:.:|.|.|..|...:.:      .:..|..:..::
plant   101 VVAIIGPGNSMQAPFLINLGNQSQVPIISFSASSPVLDSLRSPYFIRATHDDSSQVH-------- 157

  Fly   147 AYADIVQNFGWRKFTIVYDADDARAAARLQDLLQLREVHNDVVRVR---KFHKDDDF--RVMWKS 206
            |.:.|:::|.||:...:| ||:......|..|:...:..|..:|.|   ..|..||.  :.::|.
plant   158 AISAIIESFRWREVVPIY-ADNEFGEGILPYLVDAFQEINVRIRYRSAISVHSTDDLVKKELYKL 221

  Fly   207 IRGERRV-VLDCEPNMLVELLNSSTEFG-LTGQYNHIFLTNLETYTDHLEELAADNETFAVNITA 269
            :....|| ::...|::...|.:.:.|.| :|..|..|....:......:.|.:.:|....:.:..
plant   222 MTMPTRVFIVHMLPDLGSRLFSIAKEIGMMTKGYVWIVTNGIADQMSVMGESSLENMHGVLGVKT 286

  Fly   270 ARLLVNPDPPPYSLPYGYVTQRDNIVYESS-------------------DPPRTL---IHDLIHD 312
                             |.::...::|..:                   |....|   |.::..:
plant   287 -----------------YFSRSKELMYLETRWRKRFGGEELNNFECWGYDTATALAMSIEEISSN 334

  Fly   313 ALQLFAQSWRNASFFYPDRMVVPRITCDFAASGGRTWAMGRYLARL-MKGTSG--------VNNT 368
            ....|:|:.||.|   .|..........||.||.:   :.:.||.: .||.:|        :..|
plant   335 VNMSFSQTKRNTS---RDDTGTDLDDLSFALSGPK---LLQALATVSFKGVAGRFQLKNGKLEAT 393

  Fly   369 NFRTSILQFDEDGQR-----------------------ITFNIEVYDPLDGIGIAIWDPRGQITQ 410
            .|:  |:..:|.|:|                       |:.:.....|:...|..|:.|:|....
plant   394 TFK--IVNIEESGERTVGFWKSKVGLVKSLRVNQTGIKISHSSHRLRPIIWPGDTIFVPKGWEFP 456

  Fly   411 LNVDVKAQKKMIYRVATRIGPPYFSYNETARELNLTGNALYQGYAVDLIDAIARH----VGFEYV 471
            .|.     ||:  |:|......:.::.|..::.| |......|:.:|:.|...|.    |.:||:
plant   457 TNA-----KKL--RIAVPKKDGFNNFVEVTKDAN-TNAPTITGFCIDVFDTAMRQMPYAVPYEYI 513

  Fly   472 FVPVAD-QQYGKLDKETKQWNGIIGEIINNDAHMGICDLTITQARKTAVDFTVPFMQLGVSILAY 535
            .....| :..|..|:..  ::..:||.   |..:|  |.||...|.|.|||.:|:.:.|:.::..
plant   514 PFETPDGKPRGSYDEMV--YHVFLGEF---DGAVG--DTTILANRSTYVDFALPYSETGIVVVVP 571

  Fly   536 KSPHVEKTLDAYLAPFGGEVWIWILISVFVMTFLKTIVARISKMDWENPHPCNRDPEVLENQWRI 600
            .....||....:|.|...|:|.....|...:..:..|....:..|:......|          :|
plant   572 VKDEREKGKWVFLKPLTRELWFLTAASFLYIGIMVWIFEYQASGDFRKQSIIN----------KI 626

  Fly   601 HNTGWLTVASIMTAGCDILP-RSPQVRMFEATWWIFAIIIANSYTANLAAFLTSSKMEGSIANLK 664
            .|..:.:.:::..|  .:.| .|...|:....|....:|:..||||.|.:.||..::..::.::.
plant   627 SNVFYFSFSTLFFA--HMRPSESIFTRVLVVVWCFVLLILTQSYTATLTSMLTVQELRPTVRHMD 689

  Fly   665 DLSAQKKVKFGTIYGGSTYNLLADSNETVYRLAFNLMNNDDPSA-----YTKDNLEGVDRVRKNR 724
            || ....|..|...|..|:..|........|    |...|.|..     ..|.:..|:|..
plant   690 DL-RNSGVNIGYQTGSFTFERLKQMGYKESR----LKTYDTPQEMHELFLKKSSNGGIDAA---- 745

  Fly   725 GDYMFLMETTTLEYHREQNCDLRSVGE-KFGEKHYAIAVPFGAEYRSNLSVAILKLSERGELYDL 788
                 ..|...::....:.|...::.| .|....:..|.|.|:....:||..||.::|...:..:
plant   746 -----FDEVAYVKLFMAKYCSKYTIIEPTFKADGFGFAFPLGSPLVPDLSRQILNITEGETMKAI 805

  Fly   789 KQKWWKNPNASCFEEPDPDATPDM---TFEELRGIFYTLYAGILIAFLI 834
            :.||... ...|.:....|:...:   :||.|..|.:.:...:|:|.|:
plant   806 ENKWLLG-EKHCLDSTTSDSPIRLDHHSFEALFTIVFVVSMLLLLAMLV 853

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
GluRIIC	NP_608557.4	Periplasmic_Binding_Protein_type1	26..409	CDD:471960	71/387 (18%)
		PBP2_iGluR_Kainate	423..794	CDD:270432	82/382 (21%)
		Lig_chan	554..827	CDD:459656	55/282 (20%)
GLR2.6	NP_001330285.1	PBP1_GABAb_receptor_plant	38..421	CDD:380645	65/353 (18%)
		GluR_Plant	460..810	CDD:270404	83/385 (22%)
		Lig_chan	590..842	CDD:459656	55/278 (20%)