Protein Alignment GluRIIC and GLR2.4

DIOPT Version :10

• Sequence 1: NP_608557.4
• Gene: GluRIIC / 33275
• FlyBaseID: FBgn0046113
• Length: 940
• Species: Drosophila melanogaster
• Sequence 2: NP_001328410.1
• Gene: GLR2.4 / 829299
• AraportID: AT4G31710
• Length: 912
• Species: Arabidopsis thaliana
• Alignment Length: 931
• Identity: 189/931 - (20%)
• Similarity: 339/931 - (36%)
• Gaps: 218/931 - (23%)

  Fly    52 PESEQTMRFYPLIKRLKPEDGSVTMQEHACDLIDN-GVAAIFGPSSKAASDIVALVCNSTGIPHI 115
            |||...:    |:......|..|.....|.|||.| .|.||.||.:...:..|..|...:.:|.|
plant    87 PESRTRL----LLNFADSRDDVVGAAAAALDLIKNKEVKAILGPRTTMQASFVIEVGQKSQVPII 147

  Fly   116 EFDISDEGIQAEKPNHQMTLNLYPAQAILSKAYADIVQNFGWRKFTIVYD--ADDARAAARLQDL 178
            .|..:...:.:.:..:........:..:  :|.::|::.||||:...||:  |........|.|.
plant   148 SFSATSPFLDSGRSPYFFRSTYDDSSQV--QAISEIIKVFGWREVVPVYENNAFGEGIMPGLTDA 210

  Fly   179 LQ---LREVHNDVVRVRKFHKDDDFRV-MWKSIRGERRV-VLDCEPNMLVELLNSSTEFGL---- 234
            ||   :|..:..|:....  .||:..| :.|.:....|| |:.....:...:.:.:.|.||
plant   211 LQAINIRIPYRTVISPNA--TDDEISVDLLKLMTKPTRVFVVHMNRFLASRVFSKARETGLMKQG 273

  Fly   235 ------TGQYNHIFLTN------------LETYTDHLEELAADNETFAVNITAARLLVNPDPPPY 281
                  .|..:|:.|.|            :.|:....|||.......|.....:.|.:      |
plant   274 YAWILTNGVIDHLVLMNGTDIEAMQGVIGIRTHFPISEELQTFRSRLAKAFPVSELNI------Y 332

  Fly   282 SL-PYGYVTQRDNIVYESSDPPRTL-------IHDLIHDALQLFAQSWRNASFFYPDRMVVPRIT 338
            .| .|...|.....|.|:.....|.       |.||  :||.:..         |..:::
plant   333 GLRAYDATTALAMAVEEAGTTNLTFSKMDGRNISDL--EALSVSE---------YGPKLI----- 381

  Fly   339 CDFAASGGRTWAMGRYLARL-MKGTSGVNNTNFRTSILQFDEDGQRITFNIEVYDPLDGIGIAI- 401
                          |.|::: .||.||  :.:|        .|||......|:.:.:||.||.:
plant   382 --------------RSLSQIQFKGLSG--DYHF--------VDGQLHASVFEIVNVIDGGGILVG 422

  Fly   402 -W-DPRGQITQLN-----------------------VDVKAQKKMIYRVAT-----RIGPPYFSY 436
             | ..:|.:..|:                       :.:...|.  :.:.|     :||.|..::
plant   423 FWTQDKGLVKDLSPSSGTTRTFSSWKNHLNPILWPGITLTVPKG--WEIPTNGKELQIGVPVGTF 485

  Fly   437 NETARELN--LTGNALYQGYAVDLIDAIARHVGFE--YVFVPVADQQYGKLDKETKQWNGIIGEI 497
            .:..:...  ||...:..|:.:|..:|:.:.:.::  :.|:|..|.. ||.:
plant   486 PQFVKVTTDPLTHETIVTGFCIDFFEAVIQAMPYDVSHRFIPFGDDD-GKTN------------- 536

  Fly   498 INNDAHMGICDLTITQARKTAVDFTVPFMQLGVSILAYKSPHVEKTLDAYLAPFGGEVWIWILIS 562
                      |.||...|.:.||||:|:...||.::.....:|.::...:..|....:|...|.|
plant   537 ----------DTTILANRSSYVDFTLPYTTSGVGMVVPLKDNVARSSLIFFKPLTPGLWGMTLGS 591

  Fly   563 VFVMTFLKTIVARISKMDWENPHPCNRDPEVLENQWRIHNTGWLTVASIMTAGCDILPRSPQVRM 627
            .||:.|:..|:......::..|           .|::|....|...:.::.|     ||. :|..
plant   592 FFVVGFVVWILEHRVNSEFTGP-----------PQYQISTMFWFAFSIMVFA-----PRE-RVMS 639

  Fly   628 FEA-----TWWIFAIIIANSYTANLAAFLTSSKMEGSIANLKDLSAQKKVKFGTIYGGSTYNLLA 687
            |.|     ||:...:::..||||:|::.||:.::..:..::|                   |:||
plant   640 FTARVVVITWYFIVLVLTQSYTASLSSLLTTQQLNPTETSIK-------------------NVLA 685

  Fly   688 DSNETVYRLAFNLMNNDDPSAYTKDNL----------EGVDRVRKNRGDYMFLMETTTLEYHREQ 742
            ......|:....::.....|.:.:..|          |.:::.....|.....||...:.....|
plant   686 KGGPVAYQRDSFVLGKLRESGFPESRLVPFTSPEKCEELLNKGPSKGGVSAAFMEVPYVRVFLGQ 750

  Fly   743 NC-DLRSVGEKFGEKHYAIAVPFGAEYRSNLSVAILKLSERGELYDLKQKWWKNPNASCFEEPD- 805
            .| ..:.|...|....:....|.|:...:::|.||||::|..:...|:..|:||.:.:|   ||
plant   751 YCKKYKMVEVPFDVDGFGFVFPIGSPLVADVSRAILKVAESNKATQLETAWFKNIDKTC---PDP 812

  Fly   806 ---PDATPDMTFEELR-GIFYTLYAGILIAFLIGITEFLVYVQQVALEERLTFKDAFKKEIRFVL 866
               ||..|.::|.:|. ..|..|:........:.:.:|::.   ..::.|:...|.|.:..| :.
plant   813 MNNPDPNPTVSFRKLSLDSFLLLFVAAATVCTLALLKFVIC---FLIQNRIILNDEFYRGKR-MK 873

  Fly   867 CVWNNRKPIVAGTPISSVRTT 887
            .:|.........:.||.||:|
plant   874 EMWLKFMESDGESYISRVRST 894

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
GluRIIC	NP_608557.4	Periplasmic_Binding_Protein_type1	26..409	CDD:471960	86/398 (22%)
		PBP2_iGluR_Kainate	423..794	CDD:270432	78/395 (20%)
		Lig_chan	554..827	CDD:459656	63/293 (22%)
GLR2.4	NP_001328410.1	PBP1_GABAb_receptor_plant	56..434	CDD:380645	86/400 (22%)
		GluR_Plant	474..802	CDD:270404	76/387 (20%)
		Periplasmic_Binding_Protein_Type_2	482..>696	CDD:473866	54/273 (20%)