Protein Alignment GluRIIC and GLR5

DIOPT Version :10

• Sequence 1: NP_608557.4
• Gene: GluRIIC / 33275
• FlyBaseID: FBgn0046113
• Length: 940
• Species: Drosophila melanogaster
• Sequence 2: NP_565744.1
• Gene: GLR5 / 817801
• AraportID: AT2G32400
• Length: 921
• Species: Arabidopsis thaliana
• Alignment Length: 1043
• Identity: 207/1043 - (19%)
• Similarity: 365/1043 - (34%)
• Gaps: 280/1043 - (26%)

  Fly    21 RGQQINIGAFFYDD-------ELELEKEFMTVVNAINGPESEQTMRFYPLIKRLKPEDGSVTMQE 78
            |.|.:||||.|..|       ::.||    ..|:.:|..:|           .||..:..:.|::
plant    27 RPQLVNIGAVFAFDSVIGRAAKVALE----AAVSDVNNDKS-----------FLKETELRLLMED 76

  Fly    79 HAC----------DLIDNGVAAIFGPSSKAASDIVALVCNSTGIPHIEFDISDEGIQA------- 126
            .||          :|::..|.|:.||.|.:.:..::.:......|.:.|..:|..:.|
plant    77 SACNVFRGSFGAFELLEKEVVAMIGPISSSVAHTISDIAKGLHFPLVSFAATDPTLSALQFPFFL 141

  Fly   127 -EKPN--HQMTLNLYPAQAILSKAYADIVQNFGWRKFTIVYDADD--ARAAARLQDLLQLREVHN 186
             ..||  |||:            |..|::..:||::...||..|:  ....:.|.|.|..:....
plant   142 RTTPNDAHQMS------------ALVDLINFYGWKEVISVYSDDELGRNGVSALDDELYKKRSRI 194

  Fly   187 DVVRVRKFHKDDDFRV----MWKSIRGERRVVLDCEPNMLVELLNSSTEFG-LTGQYNHIFLTNL 246
            ........|.|:.|..    ..||| |.|..:|...|:.|:.:.:.:.:.. :|.:|..:....|
plant   195 SYKVPLSVHSDEKFLTNALNKSKSI-GPRVYILHFGPDPLLRIFDIAQKLQMMTHEYVWLATDWL 258

  Fly   247 ETYTDHLEELAADNETFAVNITAARLLVNPDPPPYSLPYGYVTQRDNIVYESSDPPRTLIHDLIH 311
            ....|.|.:..          |..||            .|.|..|.:|      |....:....|
plant   259 SVTLDSLSDKG----------TLKRL------------EGVVGLRQHI------PESVKMEHFTH 295

  Fly   312 D----------ALQLFAQSWR-------------NASFFYPDRMVVPRIT------CDFAASGGR 347
            .          ||..:...|.             |.:|.|.::::..|.|      ..|..||
plant   296 KLQSNRSMNAYALHAYDTVWMIAHGIEELLNEGINITFSYSEKLLHARGTKLHLEKIKFFNSG-- 358

  Fly   348 TWAMGRYLARLMKGTSGVNNTNFRTSILQFDEDGQRITFNIEV--YDPLDGIGIAIWDPRGQITQ 410
                ...|.:|:|    ||.|.....: ||......|..:.|:  .:..|...:..|...|..:.
plant   359 ----ELLLEKLLK----VNFTGIAGQV-QFGSGRNVIGCDYEIINVNKTDVHTVGFWSKNGGFSV 414

  Fly   411 LNVDVK-AQKKMIYRVATRIG----------------------------PPYFSYNETARELNLT 446
            :....: :|||..:....::|                            |...|:.|...|...:
plant   415 VAPKTRHSQKKTSFVSDEKLGDITWPGGGREKPRGWVIADSADPLKIVVPRRVSFVEFVTEEKNS 479

  Fly   447 GNALYQGYAVDLIDAIARHVGFE--YVFVPVADQQYGKLDKETKQWNGIIGEIINN--DAHMGIC 507
            .:.: ||:.:|:.....:.|.:.  |:|.|..:      ...:..:|.:|..:.:.  ||.:|
plant   480 SHRI-QGFCIDVFIEALKFVPYSVPYIFEPFGN------GHSSPNYNHLIQMVTDGVYDAAVG-- 535

  Fly   508 DLTITQARKTAVDFTVPFMQLGVSILAYKSPHVEKTLDAYLAPFGGEVWIWILISVFVMTFLKTI 572
            |:.|..:|...|||:.|:...|:.::.  ..:.:.....:|.||...:|..:|:|..|
plant   536 DIAIVPSRSKLVDFSQPYASTGLVVVI--PANDDNATWIFLRPFTSRLWCVVLVSFLV------- 591

  Fly   573 VARISKMDWENPHPCNRD----PEVLENQWRIHNTGWLTVASIMTAGCDILPRSPQ------VRM 627
               |:.:.|...|..|.|    |.        .....:.:.|..|    :..|:.:      .|:
plant   592 ---IAVVIWILEHRINEDFRGPPR--------RQLSTMLLFSFST----LFKRNQEDTISNLARL 641

  Fly   628 FEATWWIFAIIIANSYTANLAAFLTSSKMEGSIANLKDLSAQKKVKFGTIYGGSTYNLLADSNET 692
            ....|....:::..||||||.:.||..::..:|..:..|.| .:|..|  |...|:.|    ...
plant   642 VMIVWLFLLMVLTASYTANLTSILTVQQLPSAITGIDSLRA-SEVPIG--YQAGTFTL----EYL 699

  Fly   693 VYRLAF---NLMNNDDPSAYTK------DNLEGVDRVRKNRGDYMFLMETTTLEYHREQNCDLRS 748
            .|.|..   .|:..|....|.|      .|..||..:         :.|...:|....:....:.
plant   700 TYSLGMARSRLVPLDSTEEYEKALKLGPTNWGGVAAI---------VDELPYIELFLAERTGFKI 755

  Fly   749 VGEKFGEKHYAIAVPFGAEYRSNLSVAILKLSERGELYDLKQKWWKNPNASCFE--EPDPDATPD 811
            |||.|..:.:..|....:....::|.|||||||..:|.::::||....|.:...  .|:|:   .
plant   756 VGEPFMHRGWGFAFKRDSPLAIDMSTAILKLSETRKLQEIRKKWLCKTNCAGKSNWNPEPN---Q 817

  Fly   812 MTFEELRGIFYTLYAGILIAFLIGITEFLVYVQQVALEERLTFKDAFKKEIRFVLCVWNNRKPIV 876
            :..:..:|::       |:...|.::.|||:|.::           .::.:|:      .|....
plant   818 LHLKSFKGLY-------LVCIAITVSAFLVFVLRM-----------IRQFVRY------RRMERT 858

  Fly   877 AGTPISSVRTTPRRSLDKSLDRTPKSSRRVV------IGRSSEEMREMAQGSGSSSGSNNAGRGE 935
            :..|.:|...:|...|           |.:|      :....|.::.|.:.| ..|.:|.:..||
plant   859 SSMPRASWSASPTLRL-----------RELVFDFVEFVDEKEEAIKRMFRRS-DDSNNNPSHVGE 911

  Fly   936 KEA 938
            .:|
plant   912 VQA 914

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
GluRIIC	NP_608557.4	Periplasmic_Binding_Protein_type1	26..409	CDD:471960	90/447 (20%)
		PBP2_iGluR_Kainate	423..794	CDD:270432	86/421 (20%)
		Lig_chan	554..827	CDD:459656	62/293 (21%)
GLR5	NP_565744.1	PBP1_GABAb_receptor_plant	32..416	CDD:380645	90/450 (20%)
		GluR_Plant	458..800	CDD:270404	84/390 (22%)
		Lig_chan	578..832	CDD:459656	63/301 (21%)