Protein Alignment GluRIIC and GLR2.8

DIOPT Version :10

• Sequence 1: NP_608557.4
• Gene: GluRIIC / 33275
• FlyBaseID: FBgn0046113
• Length: 940
• Species: Drosophila melanogaster
• Sequence 2: NP_001324459.1
• Gene: GLR2.8 / 817459
• AraportID: AT2G29110
• Length: 948
• Species: Arabidopsis thaliana
• Alignment Length: 984
• Identity: 205/984 - (20%)
• Similarity: 369/984 - (37%)
• Gaps: 267/984 - (27%)

  Fly    14 AFFMC----------RSRGQQINIGAFFYDDELELEKEFMTV-VNAINGPESEQTMRFY------ 61
            ::|:|          :::..:|.:|..     |:|...|..: :.:||...|:    ||
plant    13 SYFVCLFLLLEVGLGQNQISEIKVGVV-----LDLNTTFSKICLTSINLALSD----FYKDHPNY 68

  Fly    62 ----PLIKRLKPEDGSVTMQEHACDLIDN-GVAAIFGPSSKAASDIVALVCNSTGIPHIEFDISD 121
                .|..|...:| :|.....|.|||.| .|:||.||.....:..:..:.|.|.:|.|.|..:.
plant    69 RTRLALHVRDSMKD-TVQASAAALDLIQNEQVSAIIGPIDSMQAKFMIKLANKTQVPTISFSATS 132

  Fly   122 EGIQAEKPNHQMTLNLYPAQAILSKAYADIVQNFGWRKFTIVYDADDARAAAR--LQDLLQLREV 184
            ..:.:.|.::.:...:..:..:  ||.|.|.::||||....:|..::......  |.|.||..:|
plant   133 PLLTSIKSDYFVRGTIDDSYQV--KAIAAIFESFGWRSVVAIYVDNELGEGIMPYLFDALQDVQV 195

  Fly   185 HNDVVRVRKFHKDDDFRVMWKSIRGERRV-VLDCEPNMLVELLNSSTEFGLTGQYNHIFL----- 243
            ...|: ..:.:.|...:.::|.:..:.|| |:.....:...:...:||.|:. :..:::|
plant   196 DRSVI-PSEANDDQILKELYKLMTRQTRVFVVHMASRLASRIFEKATEIGMM-EEGYVWLMTNGM 258

  Fly   244 TNLETYTDHLEELAADNETFAV--NITAARLL-------------VNPDPPPYSLPYGYVTQRDN 293
            |::..:..|...|...:....|  ::..::.|             .||            ..||:
plant   259 THMMRHIHHGRSLNTIDGVLGVRSHVPKSKGLEDFRLRWKRNFKKENP------------WLRDD 311

  Fly   294 I------VYESSDPPRTLIHDLIHDALQLFAQSWRNASFFYPDRMVVPRITCDFAASGGR----- 347
            :      .|:|:            .||.:..:....:||.|.:            |||..
plant   312 LSIFGLWAYDST------------TALAMAVEKTNISSFPYNN------------ASGSSNNMTD 352

  Fly   348 --TWAMGRYLARLMKGTSGVNNTNF--------------RTSILQFDEDGQRITFNIEVYDPLDG 396
              |..:.||...|::..|.:.....              :..|:.|..:.:||   :..:.|.:|
plant   353 LGTLHVSRYGPSLLEALSEIRFNGLAGRFNLIDRQLESPKFEIINFVGNEERI---VGFWTPSNG 414

  Fly   397 I----------------GIAIWDPRGQITQLNVDVKAQKKMIYRVATRIGPP----YFSYNETAR 441
            :                |..||..:..|.....::....|.|     ::|.|    :|::.|...
plant   415 LVNVNSNKTTSFTGERFGPLIWPGKSTIVPKGWEIPTNGKKI-----KVGVPVKKGFFNFVEVIT 474

  Fly   442 ELNLTGNALYQGYAVDLIDAIARHVGFEYVFVPVADQQYGKLDKETKQWNGIIGEIINNDAHMGI 506
            : .:|.....:|||:|:.:|..:.:  .|..:|    ||.:.:.....::.::.::.|......:
plant   475 D-PITNITTPKGYAIDIFEAALKKL--PYSVIP----QYYRFESPDDDYDDLVYKVDNGTLDAVV 532

  Fly   507 CDLTITQARKTAVDFTVPFMQLGVSILAYKSPHVEKTLDAYLAPFGGEVWI-----WILISVFVM 566
            .|:|||..|....|||:|:.:.|||::.....:..|....:|.|:|.::|:     ::||...|
plant   533 GDVTITAYRSLYADFTLPYTESGVSMMVPVRDNENKNTWVFLKPWGLDLWVTTACFFVLIGFVV- 596

  Fly   567 TFLKTIVARISKMDWENPHPCNRD----PEVLENQWRIHNTG---WLTVASIMTAGCDILPRSPQ 624
                          |...|..|.|    |.        |..|   |.:.::::.|..:.:. |..
plant   597 --------------WLFEHRVNTDFRGPPH--------HQIGTSFWFSFSTMVFAHREKVV-SNL 638

  Fly   625 VRMFEATWWIFAIIIANSYTANLAAFLTSSKMEGSIANLKDLSAQKKVKFGTIYGGSTYNLLADS 689
            .|.....|....:::..||||||.:|||..:.:.:..|:|||     :|.|...|
plant   639 ARFVVVVWCFVVLVLTQSYTANLTSFLTVQRFQPAAINVKDL-----IKNGDYVG---------- 688

  Fly   690 NETVYRLAFNLMNNDDPSAYTKDNL--EG--VDRVRK--NRGDYMFLMETTTLEYHREQNCDLRS 748
                |:          ..|:.||.|  ||  |.:::.  :..:...|:...::....::...||:
plant   689 ----YQ----------HGAFVKDFLIKEGFNVSKLKPFGSSEECHALLSNGSISAAFDEVAYLRA 739

  Fly   749 VGEKFGEKHYAIAVP------FGAEYRSN------LSVAILKLSERGELYDLKQKWWKNPNASCF 801
            :..::..| |||..|      ||..:..|      :|.|||.:::..|:..::.||:...| .|
plant   740 ILSQYCSK-YAIVEPTFKTAGFGFAFPRNSPLTGDVSKAILNVTQGDEMQHIENKWFMKQN-DC- 801

  Fly   802 EEPDPDATPDMTFEELRGIFYTLYAGILIAFLIGITEFLVYVQQVALEERLTFKDAFKKEIRFVL 866
              |||..........||. |:.|:   |||   ||..||..         |.|...|..|.|..|
plant   802 --PDPKTALSSNRLSLRS-FWGLF---LIA---GIASFLAL---------LIFVFLFLYENRHTL 848

  Fly   867 C------VW 869
            |      :|
plant   849 CDDSEDSIW 857

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
GluRIIC	NP_608557.4	Periplasmic_Binding_Protein_type1	26..409	CDD:471960	86/460 (19%)
		PBP2_iGluR_Kainate	423..794	CDD:270432	89/404 (22%)
		Lig_chan	554..827	CDD:459656	67/302 (22%)
GLR2.8	NP_001324459.1	PBP1_GABAb_receptor_plant	35..419	CDD:380645	83/436 (19%)
		GluR_Plant	454..795	CDD:270404	90/406 (22%)