Protein Alignment GluRIIC and GLR2.3

DIOPT Version :9

• Sequence 1: NP_608557.4
• Gene: GluRIIC / 33275
• FlyBaseID: FBgn0046113
• Length: 940
• Species: Drosophila melanogaster
• Sequence 2: NP_001325281.1
• Gene: GLR2.3 / 817007
• AraportID: AT2G24710
• Length: 919
• Species: Arabidopsis thaliana
• Alignment Length: 1035
• Identity: 201/1035 - (19%)
• Similarity: 377/1035 - (36%)
• Gaps: 294/1035 - (28%)

  Fly     7 LLGCMWSAFFMCR--SRGQQ-----INIGAFFYDDELELEKEFMTVVNA------INGPESEQTM 58
            |..|:...||.|.  :|||.     :::|. ..|.:....|..|..:|.      .:.|:.|..:
plant    30 LFFCILLVFFFCLEFNRGQNNGKTLVDVGV-VTDVDTSHSKVVMLCINMSISDFYSSNPQFETRL 93

  Fly    59 RFYPLIKRLKPEDGSVTMQEHACDLIDN-GVAAIFGPSSKAASDIVALVCNSTGIPHIEFDISDE 122
                ::.....:...|.....|.|||.| .|.||.||.:...:..:..:...:.:|.:.:..:..
plant    94 ----VVNVGDSKSDVVGAAIAALDLIKNKQVKAILGPWTSMQAHFLIEIGQKSRVPIVSYSATSP 154

  Fly   123 GIQA------EKPNHQMTLNLYPAQAILSKAYADIVQNFGWRKFTIVYDADDARAAA---RLQDL 178
            .:.:      .:..::.:..:.|.:|        |::.||||:...|| .|:.....   ||.|.
plant   155 ILTSLRSPYFLRATYEDSFQVQPIKA--------IIKLFGWREVVPVY-IDNTFGEGIMPRLTDA 210

  Fly   179 LQLREVHNDVVRVRKFHKDDDFRVMWKSIRGERRVVLDC-EPNMLVELLNSSTEFGLTGQYNHIF 242
            ||                |.:.|:.::|:     :.::. :..:.||||.      :......:|
plant   211 LQ----------------DINVRIPYRSV-----IAINATDHEISVELLK------MMNMPTRVF 248

  Fly   243 LTNLETYTDHLEELAADNETFAVNITAARLLVNPDPPPYSLPYGYVTQRDNIVYESSDPPRTLIH 307
            |.::  |.|                .|:|..:.........| |||....|.|.:.    .:||:
plant   249 LVHM--YYD----------------LASRFFIKAKELGLMEP-GYVWILTNGVIDD----LSLIN 290

  Fly   308 DLIHDA----------------LQLFAQSWRNASFFYPDRMVVPRITCDFAASGGRTWAMGRYLA 356
            :...:|                |:.|...||:         :.||:  :.:..|  .||.....|
plant   291 ETAVEAMEGVLGIKTYIPKSPDLEKFRSRWRS---------LFPRV--ELSVYG--LWAYDATTA 342

  Fly   357 RLMK-GTSGVNNTNFRTSILQFDEDGQRITFNIEVYDPLDGIGIAIWDP---------------- 404
            ..:. ..:|.||..|...:    :.|:.::       .|:.:|::.:.|
plant   343 LAVAIEEAGTNNMTFSKVV----DTGRNVS-------ELEALGLSQFGPKLLQTLLTVQFRGLAG 396

  Fly   405 -----RGQ--------ITQLNVDVKA----------------QKKMIYRVAT------------- 427
                 |||        :..:|...|:                |...|..::|
plant   397 EFRFFRGQLQPSVFEIVNIINTGEKSIGFWKEGNGLVKKLDQQASSISALSTWKDHLKHIVWPGE 461

  Fly   428 -----------------RIGPP----YFSYNETARELNLTGNALYQGYAVDLIDAIARHVGFE-- 469
                             |||.|    |....:..|: .:|.:.:..|:.:|..:|:.|.:.::
plant   462 ADSVPKGWQIPTKGKKLRIGVPKRTGYTDLVKVTRD-PITNSTVVTGFCIDFFEAVIRELPYDVS 525

  Fly   470 YVFVPVADQQYGKLDKETK-QWNGIIGEII--NNDAHMGICDLTITQARKTAVDFTVPFMQLGVS 531
            |.|:|     :.|.|.:|. .:|.::.::.  ..||.:|  |.||...|.:.||||.||::.||.
plant   526 YEFIP-----FEKPDGKTAGNYNDLVYQVYLGRYDAVVG--DTTILVNRSSYVDFTFPFIKSGVG 583

  Fly   532 ILAYKSPHVEKTLDAYLAPFGGEVWIWILISVFVMTFLKTIVARISKMDWENPHPCNRDPEVLEN 596
            ::...:..|::....::.|...::|:...||.|::.....::......|:..|           .
plant   584 LIVEMTDPVKRDYILFMKPLSWKLWLTSFISFFLVGCTVWVLEYKRNPDFSGP-----------P 637

  Fly   597 QWRIHNTGWLTVASIMTAGCDILPRSPQVRMFE-------ATWWIFAIIIANSYTANLAAFLTSS 654
            :::.....|...::::.|        |:.|:|.       ..|:...:::..||||:||:.|||.
plant   638 RFQASTICWFAFSTMVFA--------PRERVFSFWARALVIAWYFLVLVLTQSYTASLASLLTSQ 694

  Fly   655 KMEGSIANLKDLSAQKKVKFGTIYGGSTYNLLADSNETV--YRLAF---NLMNNDDP--SAYTKD 712
            |:..:|.::..                    |.:..|||  .|.:|   .|.....|  |....|
plant   695 KLNPTITSMSS--------------------LLEKGETVGYQRTSFILGKLKERGFPQSSLVPFD 739

  Fly   713 NLEGVDRV----RKNRGDYMFLMETTTLEYHREQNCD-LRSVGEKFGEKHYAIAVPFGAEYRSNL 772
            ..|..|.:    .|..|.....:|...|.....|.|: .:.|.|.|....:....|.|:...:::
plant   740 TAEECDELLSKGPKKGGVSGAFLEIPYLRLFLGQFCNTYKMVEEPFNVDGFGFVFPIGSPLVADV 804

  Fly   773 SVAILKLSERGELYDLKQKWWKNPNASCFEEPD----PDATPDMTFEELR-GIFYTLYAGILIAF 832
            |.||||::|..:..:|::.|:|....||   ||    ||..|..|..:|. ..|..|:.|:|:..
plant   805 SRAILKVAESPKAMELERAWFKKKEQSC---PDPITNPDPNPSFTSRQLDIDSFLFLFVGVLLVC 866

  Fly   833 LIGITEFLVYVQQVALEERLTFKDAFKKEIRFVLCVWNNRKPIVAGTPISSVRTTPRRSL 892
            ::.:..| .|.  ...::::::.|    ::....|..:.:.|:...|.::..:...:.||
plant   867 VMALGNF-TYC--FLAKDQVSYLD----KVEMSPCSSSQQMPVKRKTQLNMSQVHDQDSL 919

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
GluRIIC	NP_608557.4	PBP1_iGluR_Kainate	26..404	CDD:107377	73/411 (18%)
		Periplasmic_Binding_Protein_Type_1	<279..363	CDD:299141	19/100 (19%)
		PBP2_iGluR_Kainate	423..794	CDD:270432	90/428 (21%)
		Lig_chan	554..828	CDD:278489	66/297 (22%)
GLR2.3	NP_001325281.1	None

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	82	0.746	Domainoid score	I2907
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	137	1.000	Inparanoid score	I1813
OMA	1	1.010	-	-		QHG60082
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000021
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR18966
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	6	6.070