Protein Alignment GluRIIC and GLR2

DIOPT Version :10

• Sequence 1: NP_608557.4
• Gene: GluRIIC / 33275
• FlyBaseID: FBgn0046113
• Length: 940
• Species: Drosophila melanogaster
• Sequence 2: NP_001318239.1
• Gene: GLR2 / 816231
• AraportID: AT2G17260
• Length: 925
• Species: Arabidopsis thaliana
• Alignment Length: 968
• Identity: 198/968 - (20%)
• Similarity: 338/968 - (34%)
• Gaps: 288/968 - (29%)

  Fly    80 ACDLIDNGVAAIFGPSSKAASDIVALVCNSTGIPHIEFDISDEGIQ-AEKPNHQMTLNLYPAQAI 143
            |...::..|.||.||.:...:.:::.:.|...:|.:.|...|..:. .:.|....|.   |:...
plant    91 ALQFMETDVVAIIGPQTSIMAHVLSHLANELTVPMLSFTALDPTLSPLQFPFFVQTA---PSDLF 152

  Fly   144 LSKAYADIVQNFGWRKFTIVYDADD--ARAAARLQDLLQLR--------------------EVHN 186
            |.:|.|:::..:||.....:|:.||  ......|.|.|:.|                    |:..
plant   153 LMRAIAEMITYYGWSDVVALYNDDDNSRNGVTALGDELEERRCKISYKAVLPLDVVITSPVEIIE 217

  Fly   187 DVVRVRKFHKDDDFRVMWKSIRGERRVVLDCEPNMLVELLNSSTEFGLTGQ-YNHIFLTNLETYT 250
            :::::|...              .|.:|::..||....:...:...|:..: |..|..|.|.:..
plant   218 ELIKIRGME--------------SRVIVVNTFPNTGKMIFKEAERLGMMEKGYVWIATTWLSSVL 268

  Fly   251 DHLEELAADNETFAVNITAARLLVNPDPPPYSLPYGYVTQRDNIVYESSDPPRTLIHDLIHDALQ 315
            |  ..|..|  |..||......|..||..         .:||
plant   269 D--SNLPLD--TKLVNGVLTLRLHTPDSR---------KKRD----------------------- 297

  Fly   316 LFAQSWRN-------------ASFFYPDRMVVPRITCDFAASGG-----RTWAMGRY-------- 354
             ||..|:|             ..:.|....::.|.......:||     ....:|..
plant   298 -FAARWKNKLSNNKTIGLNVYGLYAYDTVWIIARAVKTLLEAGGNLSFSNDAKLGSLKGEALNLS 361

  Fly   355 -LARLMKGT-----------SGVNNTNFRTSILQFDEDGQRITFNIEVYDPLD------------ 395
             |:|..:|:           ||:      |..:||..|...:..:.::.:.:|
plant   362 ALSRFDQGSQLLDYIVHTKMSGL------TGPVQFHPDRSMLQPSYDIINLVDDRVHQIGYWSNY 420

  Fly   396 -GIGI----------------------AIW------DPRGQITQLNVDVKAQKKMIYRVATRIG- 430
             |:.|                      ..|      .|||.|.:.|     .:::      |||
plant   421 SGLSIVPPESFYSKPPNRSSSNQHLNSVTWPGGTSVTPRGWIFRNN-----GRRL------RIGV 474

  Fly   431 PPYFSYNETARELNLTGNALYQGYAVDLIDAIARHVGF----EYVFVPVADQQYGKLDKETK-QW 490
            |...|:.:....:|.:.|.: |||.:|:.:|..:.:.:    |::|       :|  |..|. .:
plant   475 PDRASFKDFVSRVNGSSNKV-QGYCIDVFEAAVKLLSYPVPHEFIF-------FG--DGLTNPNY 529

  Fly   491 NGIIGEI---INNDAHMGICDLTITQARKTAVDFTVPFMQLGVSILAYKSPHVEKTLDAYLAPFG 552
            |.::.::   ::.||.:|  |:.|...|...||||.|:::.|:.::| ....:.:...|:|.||.
plant   530 NELVNKVTTGVDFDAVVG--DIAIVTKRTRIVDFTQPYIESGLVVVA-PVTRLNENPWAFLRPFT 591

  Fly   553 GEVWIWILISVFVMTFLKTIVARISKMDWENPHPCN---RDP---EVLENQWRIHNTGWLT--VA 609
            ..:|. :..|.||:         :....|...|..|   |.|   :::...|...:|.:.:  ..
plant   592 LPMWA-VTASFFVI---------VGAAIWILEHRINDEFRGPPRRQIITILWFTFSTMFFSHRET 646

  Fly   610 SIMTAGCDILPRSPQVRMFEATWWIFAIIIANSYTANLAAFLTSSKMEGSIANLKDL-SAQKKVK 673
            ::.|.|          ||....|....:||.:||||:|.:.||..::...|..:..| |:..::.
plant   647 TVSTLG----------RMVLLIWLFVVLIITSSYTASLTSILTVQQLNSPIKGVDTLISSTGRIG 701

  Fly   674 FGTIYGGSTYNLLADS-NETVYRLA--------FNLMNNDDPSAYTKDNLEGVDRVRKNRGDYMF 729
            |..  |....|.:.|. |....||.        .|.:.|...:|.. |....:|         :|
plant   702 FQV--GSFAENYMTDELNIASSRLVPLASPEEYANALQNGTVAAIV-DERPYID---------LF 754

  Fly   730 LMETTTLEYHREQNCDLRSVGEKFGEKHYAIAVPFGAEYRSNLSVAILKLSERGELYDLKQKWWK 794
            |.:          .|.....|::|....:..|.|..:....::|.|||.|||.|||..:..:|..
plant   755 LSD----------YCKFAIRGQEFTRCGWGFAFPRDSPLAVDMSTAILGLSETGELQKIHDRWLS 809

  Fly   795 NPNASCFEEPDPDATPDMTFEELR-----GIFYTLYAGILIAFLIG----ITEFLVYVQQVALEE 850
            ..|.|     .|..:.....|:|.     |:|..:....|:|..|.    |.:|.....:|.:||
plant   810 KSNCS-----SPHGSQSGDSEQLNVHSFWGMFLVVGIACLVALFIHFFKIIRDFCKDTPEVVVEE 869

  Fly   851 --------RLT-------FKDAFKKEI-RFVLCVWNNRKPIVAGTPISSVRTTPRRSL 892
                    |||       |.|..::|. |.:....||...:.|.:.||  ||..||.:
plant   870 AIPSPKSSRLTKLQTFLAFVDEKEEETKRRLKRKRNNDHSMNANSIIS--RTASRRPI 925

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
GluRIIC	NP_608557.4	Periplasmic_Binding_Protein_type1	26..409	CDD:471960	72/431 (17%)
		PBP2_iGluR_Kainate	423..794	CDD:270432	93/397 (23%)
		Lig_chan	554..827	CDD:459656	65/295 (22%)
GLR2	NP_001318239.1	PBP1_GABAb_receptor_plant	35..427	CDD:380645	68/395 (17%)
		GluR_Plant	468..808	CDD:270404	92/400 (23%)
		Lig_chan	591..842	CDD:459656	65/297 (22%)