Protein Alignment GluRIIC and grid1b

DIOPT Version :9

• Sequence 1: NP_608557.4
• Gene: GluRIIC / 33275
• FlyBaseID: FBgn0046113
• Length: 940
• Species: Drosophila melanogaster
• Sequence 2: XP_009304811.1
• Gene: grid1b / 557511
• ZFINID: ZDB-GENE-121214-84
• Length: 1048
• Species: Danio rerio
• Alignment Length: 1026
• Identity: 246/1026 - (23%)
• Similarity: 420/1026 - (40%)
• Gaps: 189/1026 - (18%)

  Fly     6 LLLGCMWSAFFMCRSRGQQ--INIGAFFYDDELELEKEFMTVVNAIN-GPESEQTMRFYPLIKRL 67
            ||:.|:......|.|.|..  |:|||.|.::....::.|...::.:: ..:..|:.:....||.:
Zfish     3 LLIICLSFGILQCSSAGADSIIHIGAIFEENAARDDEVFQLAISDLSLNDDILQSEKITHSIKYI 67

  Fly    68 KPEDGSVTMQEHACDLIDNGVAAIFGPSSKAASDIVALVCNSTGIPHIEFDISDEGIQAEKPNHQ 132
            :|.:....:|| ||:|:..|:.|:...:..|::..:..:.::..|||:....:.||    .|...
Zfish    68 EPNNPFQAVQE-ACELMTQGILALVTSTGCASASALQSLTDAMHIPHLYVQRNAEG----SPRTA 127

  Fly   133 MTLNLYP----------AQAILSKAYADIVQNFGWRKFTIVYDAD-DARAAARLQDL-------L 179
            ..||..|          ....|......:|....|:||.:.||:| |.|......|.       :
Zfish   128 CQLNPSPDGERYTLAARPPVRLGDVMLTLVGELRWQKFIVFYDSDYDIRGLQVFLDQTSRQGLDV 192

  Fly   180 QLREVHNDVVRVRKFHKDDDFRVMWKSIRGE---------RRVVLDCEPNMLVELLNSSTEFGLT 235
            .|:.|..::..|        |..::.|:|.|         ||.:|...|......::.:.|..|.
Zfish   193 SLQRVDRNISGV--------FSSLFTSMRTEELNRYRDTLRRAILLLSPRGAQVFIHQAVETNLA 249

  Fly   236 GQYNHIFLTNLETYTDHLEELAADNETFAVNITAARLLVNPDPPPYSLPYGYVTQRDNIV----- 295
            .:.:|....|.|.....:.|||   .:....:|..|.:             :...||:.|
Zfish   250 SKDSHWVFVNEEISDTEILELA---HSSLGRMTVVRQI-------------FPLWRDSSVSCMRN 298

  Fly   296 -YESS----DPPRTLIHDLIHDALQLFAQSWRNASFFYPDRMVVPRITCDFAA-----------S 344
             :..|    ||....:..|....|.|:......|:.||  |.:..|.....|:           :
Zfish   299 SHRISSLLCDPQEGYLQSLEVSNLYLYDSVLMLANAFY--RKLEDRKWHSMASLNCIRKSTKPWN 361

  Fly   345 GGRTWAMGRYLARLMKG-TSGVNNTNFRTSILQFDEDGQRITFNIEVYDPLDGIG---------- 398
            ||  |:|   |..:.|| .:|:      |.|:.|.|:|.......|:      :|
Zfish   362 GG--WSM---LETIQKGRITGL------TGIMDFMENGSNSHVQFEI------LGTSFSETFGKD 409

  Fly   399 ---IAIWDP----RGQITQLNVDVKAQKKMIYRVATRIGPPYFSYNETARELNLTGN-ALYQGYA 455
               :|.||.    .|.:.:..:: ...:.:..:|.|.:..|:....|     |:.|. ..|:|::
Zfish   410 IKRLATWDSVHGLNGSLKESRIE-NGMQGVTVKVVTLLEDPFVMVAE-----NILGQPKRYKGFS 468

  Fly   456 VDLIDAIARHVGFEYVFVPVADQQYGKLDKETKQWNGIIGEIINNDAHMGICDLTITQARKTAVD 520
            :|:::|:|:.:||:|....|||.:||. ......|||:|||:||..|.:.:..:|||..|:..||
Zfish   469 IDVLEALAKILGFKYDIYQVADSKYGS-QLSNGSWNGMIGELINKRADLAVSAITITPERENVVD 532

  Fly   521 FTVPFMQLGVSILAYKSPHVEKTLDAYLAPFGGEVWIWILISVFVMTFLKTIVARISKMDWENPH 585
            |:..:|...|.|| ::.|..:..:.:..|||...||..|..::.|:..|..::.|:..:..:||
Zfish   533 FSKRYMDYSVGIL-HRKPEEKINIFSLFAPFDLAVWACIAAAIPVVGVLIFLLTRMQMLRSQNP- 595

  Fly   586 PCNRDPEVLENQWRIHNTGWLTVASIMTAGCDILPRSPQVRMFEATWWIFAIIIANSYTANLAAF 650
            |.......:.|.  :|:..|:...:.:..|.|.:..|..:|:...:||:|.:|:.:|||||||||
Zfish   596 PGAHHASSMSNS--LHSAIWIVYGAFVQQGGDSVVGSVALRIVMGSWWLFTLIVCSSYTANLAAF 658

  Fly   651 LTSSKMEGSIANLKDLSAQKKVKFGTIYGGSTYNLL-------ADSNETVYRLAFNLMNNDDPSA 708
            ||.|:|:.:|...:||:.|....:||:...:.|:..       .:.:.|...|...:..|:....
Zfish   659 LTVSRMDNTIRTFQDLARQMDFAYGTVRDSAVYDYFKAKGTNPLEQDSTYAELWRTISKNNGQDF 723

  Fly   709 YTKDNLEGVDRVRKNRGDYMFLMETTTLEYH--REQNCDLRSVGEKFGEKHYAIAVPFGAEYRSN 771
            ......||:.:.:|  |.|.||.:...:||.  .:.:|.:...|.....|.|.||:..|:.||..
Zfish   724 SVSSPSEGIRKAKK--GPYAFLWDMAVVEYAALTDDDCTITVSGNSMSSKGYGIAMQHGSPYRDL 786

  Fly   772 LSVAILKLSERGELYDLKQKWWKNPNASCFEEPDPDATPD---MTFEELRGIFYTLYAGILIAFL 833
            :|..||:|.|:|:|..||||||.. ...|......:|.||   :......|:|..|.||:|:|.|
Zfish   787 ISQKILELQEKGDLDVLKQKWWPR-TGRCDLNSHSNAQPDGRSLKLHSFAGVFCILAAGLLLACL 850

  Fly   834 IGITEF--------LVYVQQVALEER-------LTFKDAFKKEIRFVLCVWNNRKPIVAGTPISS 883
            :...|.        ....::|..:.|       ||:.|...........:|.:|:
Zfish   851 VAALEMWWNSNRCRQEQPKEVTKDYRLARVSGPLTYNDIATASSEGSKDIWTDRE---------- 905

  Fly   884 VRTTPRRSLDKSLDRTPKSSRRVVIGRSSEEMREMAQGSGSSSGSNNAGRG 934
                  |..|:        :..:..|:..|      .|:|:|:.....|||
Zfish   906 ------RDWDE--------AEAIDTGQGGE------PGTGASAFEQPYGRG 936

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
GluRIIC	NP_608557.4	PBP1_iGluR_Kainate	26..404	CDD:107377	90/440 (20%)
		Periplasmic_Binding_Protein_Type_1	<279..363	CDD:299141	22/105 (21%)
		PBP2_iGluR_Kainate	423..794	CDD:270432	116/380 (31%)
		Lig_chan	554..828	CDD:278489	82/285 (29%)
grid1b	XP_009304811.1	PBP1_iGluR_delta_1	25..424	CDD:107387	91/446 (20%)
		ANF_receptor	36..400	CDD:279440	83/411 (20%)
		Periplasmic_Binding_Protein_Type_2	437..809	CDD:304360	116/383 (30%)
		Lig_chan	565..840	CDD:278489	80/280 (29%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170590992
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000021
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.840