Protein Alignment GluRIIC and KaiR1D

DIOPT Version :10

• Sequence 1: NP_608557.4
• Gene: GluRIIC / 33275
• FlyBaseID: FBgn0046113
• Length: 940
• Species: Drosophila melanogaster
• Sequence 2: XP_061498559.1
• Gene: KaiR1D / 4576020
• VectorBaseID: AGAMI1_006981
• Length: 930
• Species: Anopheles gambiae
• Alignment Length: 932
• Identity: 301/932 - (32%)
• Similarity: 495/932 - (53%)
• Gaps: 72/932 - (7%)

  Fly    10 CMWSAFFM---------CRSRGQQINIGAFFYDDELELEKEFMTVVNAINGPESEQTM----RFY 61
            |.|:|..:         .|:....|.||..|:.|:...|..|...|..||   |::|:    :..
Mosquito     9 CWWAACLLALLLHGPAPARALPDAIRIGGLFHPDDDHQEIAFRYAVEKIN---SDRTILPRSKLL 70

  Fly    62 PLIKRLKPEDGSVTMQEHACDLIDNGVAAIFGPSSKAASDIVALVCNSTGIPHIEFDISDEGIQA 126
            ..|:|:.|:| |....:..|.|:..||||||||.|...:..|..:|::..|||:| ...|..::.
Mosquito    71 AQIERISPQD-SFLASKRVCHLLGVGVAAIFGPQSSHTASHVQSICDTMEIPHLE-TRWDYRLRR 133

  Fly   127 EKPNHQMTLNLYPAQAILSKAYADIVQNFGWRKFTIVYDADDARAAARLQDLLQLREVHNDVVRV 191
            |    ...:||||..:.|||||.|:|..:||:.|||:|:.::  ...|:|:||:...:.:..:.|
Mosquito   134 E----SCLVNLYPHPSTLSKAYVDLVAAWGWKSFTIIYETNE--GLVRMQELLKAHGLSDYPITV 192

  Fly   192 RKFHKDDDFRVMWKSIR--GERRVVLDCEPNMLVELLNSSTEFGLTGQYNHIFLTNLETYTDHLE 254
            |:.....|:|.:.|.|:  .|..:||||....:.|:|..:.:.|:...|:...:|:|:.:|.:|:
Mosquito   193 RQLSDSGDYRPLLKQIKNSAESHIVLDCSTERIYEVLKQAQQIGMMSDYHSYLITSLDLHTINLD 257

  Fly   255 ELAADNETFAVNITAARLLVNPDPPP-----YSLPYGYVTQRDNIVYESSDPPRTLIHD--LIHD 312
            |.    :....||||.| ||:|:.|.     ::...|.......:.:::::....:..:  |::|
Mosquito   258 EF----KYGGTNITAFR-LVDPENPEVAQAIHNWTIGEARLGKKVDFKTAENVTVIKAETALMYD 317

  Fly   313 ALQLFAQSWRNASFFYPDRMVVPRITCDFAASGGRTWAMGRYLARLMKGTSGVNNTNFRTSILQF 377
            |:.|||::..:..  ...::.:..::||..    .||..|..|...||    :......|.:::|
Mosquito   318 AVHLFAKALHDLD--TSQQIDIHPLSCDTQ----DTWPHGYSLINYMK----IVEMRGLTDVIKF 372

  Fly   378 DEDGQRITFNIEVYD--PLDGI----------GIAIWDPRGQITQLNVDVKAQKKMIYRVATRIG 430
            |..|.|..|.:::.:  | .|:          |:......|:..:..|::...|.:|  |.|.:.
Mosquito   373 DHQGFRSDFVLDIVELGP-QGLRKSGTWNSTSGVNFTRTYGEQQKEIVEILQNKTLI--VTTILS 434

  Fly   431 PPYFSYNETARELNLTGNALYQGYAVDLIDAIARHVGFEYVFVPVADQQYGKLDKETKQWNGIIG 495
            .||....::|.:  ||||:.::|||:|||..|::.:||.|......|.:||..:|||.:|:|:|.
Mosquito   435 APYCMRKDSAEK--LTGNSQFEGYAIDLIHEISKILGFNYTIRLAPDGRYGSHNKETGEWDGMIK 497

  Fly   496 EIINNDAHMGICDLTITQARKTAVDFTVPFMQLGVSILAYKSPHVEKTLDAYLAPFGGEVWIWIL 560
            |::...|.:.|.|||||..|:..||||:|||.||:|:|..|.......|.::|:|...:|||::.
Mosquito   498 ELLEQRADLAIADLTITFDREQVVDFTMPFMNLGISVLYRKPVKQPPNLFSFLSPLSLDVWIYMA 562

  Fly   561 ISVFVMTFLKTIVARISKMDWENPHPCNRDPEVLENQWRIHNTGWLTVASIMTAGCDILPRSPQV 625
            .:...::.|..|:||.:..:|..|:||:..||.|:.|:.:.|..|..:.|:|..|||.||::...
Mosquito   563 TAYLGVSVLLFILARFTPYEWPTPNPCDPHPEKLQTQFTLMNCMWFAIGSLMQQGCDFLPKAVST 627

  Fly   626 RMFEATWWIFAIIIANSYTANLAAFLTSSKMEGSIANLKDLSAQKKVKFGTIYGGSTYNLLADSN 690
            ||....||.|.:|:.:|||||||||||..:|:..|.:.:||:.|.|:|:|.:.||||.....|||
Mosquito   628 RMVAGMWWFFTLIMISSYTANLAAFLTVERMDSPIESAEDLAKQTKIKYGALRGGSTAAFFRDSN 692

  Fly   691 ETVYRLAFNLMNNDDPSAYTKDNLEGVDRVRKNRGDYMFLMETTTLEYHREQNCDLRSVGEKFGE 755
            .:.|:..::.|.:..||.:|..|:|||:||.|.:|.|.||||:|::||..|:||:|..||.....
Mosquito   693 FSTYQRMWSFMESARPSVFTASNIEGVERVVKGKGSYAFLMESTSIEYVIERNCELTQVGGMLDS 757

  Fly   756 KHYAIAVPFGAEYRSNLSVAILKLSERGELYDLKQKWWKNP--NASCFEEPDPDATP--DMTFEE 816
            |.|.||:|..:.:|:.:|.|:|||.|.|:|:.||.:|||..  ..||.::....::.  ::....
Mosquito   758 KGYGIAMPPNSPFRTAISGAVLKLQEEGKLHILKTRWWKEKRGGGSCRDDTSKSSSTANELGLAN 822

  Fly   817 LRGIFYTLYAGILIAFLIGITEFLVYVQQVALEER-LTFKDAFKKEIRFVLCVWNNRKPIVAGTP 880
            :.|:|..|..|:.:|.:|.:.||:...::||:||| ::.......|:||.| ..|..:|..||:.
Mosquito   823 VGGVFVVLMGGMGVACVIAVCEFVWKSRKVAVEEREVSLCSEMASELRFAL-KRNRAQPKHAGSG 886

  Fly   881 ISSVRTTPRRSLDKSLDRTPKS 902
             .::||...|:..|.....|.|
Mosquito   887 -GTLRTASSRASPKDSASEPSS 907

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
GluRIIC	NP_608557.4	Periplasmic_Binding_Protein_type1	26..409	CDD:471960	110/407 (27%)
		PBP2_iGluR_Kainate	423..794	CDD:270432	152/370 (41%)
		Lig_chan	554..827	CDD:459656	107/276 (39%)
KaiR1D	XP_061498559.1	None