Protein Alignment GluRIIC and grin2da

DIOPT Version :9

• Sequence 1: NP_608557.4
• Gene: GluRIIC / 33275
• FlyBaseID: FBgn0046113
• Length: 940
• Species: Drosophila melanogaster
• Sequence 2: XP_009292354.1
• Gene: grin2da / 449864
• ZFINID: ZDB-GENE-041008-124
• Length: 1916
• Species: Danio rerio
• Alignment Length: 921
• Identity: 174/921 - (18%)
• Similarity: 334/921 - (36%)
• Gaps: 303/921 - (32%)

  Fly    72 GSVTMQEHACDLIDNGVAAIFG----------PSSKAASDIVALVCNSTGIPHIEFDISDEGIQA 126
            ||:.:|  .|:|:  ....:.|          |:....:.::..|...||:|.|... ...|:..
Zfish   124 GSLLLQ--LCELL--ATTPLQGLVFEEEKPPPPNRAPLAPMLEFVSAQTGVPVIAVG-GGAGLGR 183

  Fly   127 E-KPNHQMTLNLYPAQAILSKAYADIVQNFGWRKFTIVYDADDARAAARLQDLLQLREVHNDVVR 190
            | :.:..:.|....:..:..:...::::.|.|..|::|
Zfish   184 EPQESGSVYLQFSCSTDLQLEVIFEVLEEFDWTAFSVV--------------------------- 221

  Fly   191 VRKFHKDDDFRVMWKS------IRGERRVVLDCEPNMLVELLNSSTEFGLTGQYNHIFLTNLETY 249
            ..:.|..:||..|.:.      |..||:.|:         :||.:.:.|
Zfish   222 TTRHHGYEDFLAMVEGMIDGSFIGWERKSVV---------MLNLTDDPG---------------- 261

  Fly   250 TDHLEELAADNETFAVNITAARLLVNPDPPPYSLPYGYVTQRDNIVYESSDPPRTLIHDLIHDAL 314
            ......|..:||      ...|||             |.:|                    .:|.
Zfish   262 GARTRRLLKENE------AQVRLL-------------YCSQ--------------------EEAE 287

  Fly   315 QLFAQSWRNASFFYPDRMVVPRITCDFAASGGRT----W-AMGRYLA------------------ 356
            |:|..:|                     |||..|    | |:|..|:
Zfish   288 QIFKAAW---------------------ASGQATPSHMWFAVGPGLSGLGLEGLPKALFAVRPQG 331

  Fly   357 -------RLMKGTS--------------GVNNTNFRTSILQFDEDGQRI---------------- 384
                   |:.||.|              |...|:|..:.:......||:
Zfish   332 WRDEPRRRIAKGVSVLTHGAMALRREYGGARGTSFAGNCMMDGNQTQRVPGRIRFFSNITLSGRD 396

  Fly   385 -TFNIEVY--DPL------------DGIGIAIWDPRGQITQLNVDVKAQKKMIYRVATRIGPPYF 434
             :||.:.|  :||            :.:|   |...|.:           ::.|...:|.| |:.
Zfish   397 YSFNNDGYLANPLLDVISYTAGRGWEEVG---WWENGVL-----------RLRYPPWSRYG-PFL 446

  Fly   435 SYNETARELNL-----------------TGNAL-------------------------YQGYAVD 457
            ...:.::.|.:                 ||:.:                         .:|:.:|
Zfish   447 KPLDDSQHLRVVTLEERPFVIVEPADPGTGSCIRDSVPCRLPLNNSMVVEGIQSMKHCCKGFCID 511

  Fly   458 LIDAIARHVGFEYVFVPVADQQYGK-LDKETKQWNGIIGEIINNDAHMGICDLTITQARKTAVDF 521
            ::..:|:.|||.|....|.:.::|| :|   .||||::||:::..|.|.|..|||.:.|...|:|
Zfish   512 VLKRLAKIVGFTYDLYLVTNGRHGKNID---GQWNGMVGEVVSKRADMAIGSLTINEERSEVVEF 573

  Fly   522 TVPFMQLGVSILAYKSPHVEKTLDAYLAPFGGEVWIWILISVFVMTFLKTIVARISKMDWENPHP 586
            :|||::.|:|::..:| :...:..|:|.|:...||    :.:|||. |..:...:...::.:|..
Zfish   574 SVPFVETGISVMVSRS-NGTVSPSAFLEPYSPAVW----VMMFVMC-LSVVAVTVFIFEFFSPVG 632

  Fly   587 CNRDPEVLE----NQWRIHNTGWLTVASIMTAGCDI-LPRSPQVRMFEATWWIFAIIIANSYTAN 646
            .||..:..:    :::.|..:.||..|.:......: .||....::....|..||:|...|||||
Zfish   633 YNRSLQSGKTAGGSKFTIGKSIWLLWALVFNNSVPVENPRGTTSKIMVLVWAFFAVIFLASYTAN 697

  Fly   647 LAAFLTSSKMEGSIANLKDLSAQ------KKVKFGTIYGGSTYNLLADSNETVYRLAFNLMNNDD 705
            ||||:...:...:::.|.|...|      ..::|||:..|||...:..:...:::  :.:.||.
Zfish   698 LAAFMIQEEYIDTVSGLSDKKFQHPTEQYPPLRFGTVPNGSTEENIRSNYPNMHQ--YMVRNNQ- 759

  Fly   706 PSAYTKDNLEGVDRVRKNRGDYMFLMETTTLEY--HREQNCDLRSV--GEKFGEKHYAIAVPFGA 766
                 :...:.::.::..:.| .|:.:...|.|  .:::.|.:.::  |:.|....|.:|:...:
Zfish   760 -----RGVEDAIENLKTGKLD-AFIYDAAVLNYMARKDEGCKVMTIGSGKVFATTGYGVALHKNS 818

  Fly   767 EYRSNLSVAILKLSERGELYDLKQKWWKNPNASCFEEPDPDATPDMTFEELRGIFYTLYAGILIA 831
            .::..|.:|:|:|....|: |:.::.|.  :..|..:.....:..:..:.:.|:||.|...:.::
Zfish   819 RWKRPLDLALLQLVGDDEI-DMLERLWL--SGICHNDKIEVMSSKLDIDNMAGVFYMLLVAMGLS 880

  Fly   832 FLIGITEFLVY 842
            .|:...|.|||
Zfish   881 LLVFAWEHLVY 891

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
GluRIIC	NP_608557.4	PBP1_iGluR_Kainate	26..404	CDD:107377	66/423 (16%)
		Periplasmic_Binding_Protein_Type_1	<279..363	CDD:299141	17/113 (15%)
		PBP2_iGluR_Kainate	423..794	CDD:270432	96/428 (22%)
		Lig_chan	554..828	CDD:278489	60/288 (21%)
grin2da	XP_009292354.1	PBP1_iGluR_NMDA_NR2	42..441	CDD:107373	68/447 (15%)
		PBP2_iGluR_NMDA_Nr2	452..851	CDD:270436	94/419 (22%)
		HisJ	<507..>590	CDD:223904	32/86 (37%)
		Lig_chan	605..877	CDD:278489	60/288 (21%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170591036
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.840