Protein Alignment GluRIIC and GluRIID

DIOPT Version :10

• Sequence 1: NP_608557.4
• Gene: GluRIIC / 33275
• FlyBaseID: FBgn0046113
• Length: 940
• Species: Drosophila melanogaster
• Sequence 2: NP_651982.1
• Gene: GluRIID / 44483
• FlyBaseID: FBgn0028422
• Length: 902
• Species: Drosophila melanogaster
• Alignment Length: 923
• Identity: 258/923 - (27%)
• Similarity: 429/923 - (46%)
• Gaps: 112/923 - (12%)

  Fly    20 SRGQQINIGAFFYDDELELEKEFMTVVNAINGP-------ESEQTMRFYPLIKRLKPEDGSVTMQ 77
            |.||.|.:|....|....:.:.|...::.:|..       |:||.           ....||...
  Fly    29 SSGQSIRLGLITDDATDRIRQTFEHAISVVNNELGVPLVGETEQV-----------AYGNSVQAF 82

  Fly    78 EHACDLIDNGVAAIFGPSSKAASDIVALVCNSTGI----PHIEFDISDEGIQAEKPNHQMTLNLY 138
            ...|.|:.:||.|:|||:::..:..:...|:|..|    ||:.:..:.:|           .||:
  Fly    83 AQLCRLMQSGVGAVFGPAARHTASHLLNACDSKDIPFIYPHLSWGSNPDG-----------FNLH 136

  Fly   139 PAQAILSKAYADIVQNFGWRKFTIVYDADDARAAARLQDLLQLREVHNDVVRVRKF--HKDDDFR 201
            |:...::.|..|||..|.|.:|...|::  |.....|..|:....:...|::|.::  :.:.:::
  Fly   137 PSPEDIANALYDIVNQFEWSRFIFCYES--AEYLKILDHLMTRYGIKGPVIKVMRYDLNLNGNYK 199

  Fly   202 VMWKSIR--GERRVVLDCEPNMLVELLNSSTEFGLTGQ-YNHIFLTNLETYTDHLEELAADNETF 263
            .:.:.||  .:.|:|:......:.|||..:.:.|:..: |.:| :.||..:|..|||.....
  Fly   200 SVLRRIRKSEDSRIVVVGSTTGVAELLRQAQQVGIMNEDYTYI-IGNLNLHTFDLEEYKYSE--- 260

  Fly   264 AVNITAARLLVNPD-----------------PPPYSLPYGYVTQRDNIVYES-----------SD 300
             .|||..|:. :||                 ..|.:....::|....:.|::           ..
  Fly   261 -ANITGIRMF-SPDQEEVRDLMEKLHQELGESEPVNSGSTFITMEMALTYDAVRVIAETTKHLPY 323

  Fly   301 PPRTLIHDLIHDALQLFAQSWRN--ASFFYPDRMVVPRITCDFAASGGRTW-AMGRYLARLMKGT 362
            .|:.|.....||.:|....::||  .|....::.:..||..:.....|.|: .:....:.|:|..
  Fly   324 QPQMLNCSERHDNVQPDGSTFRNYMRSLEIKEKTITGRIYFEGNVRKGFTFDVIELQTSGLVKVG 388

  Fly   363 SGVNNTNFRTSILQFDEDGQRITFNIEVYDPLDGIGIAIWDPRGQITQLNVDVKAQKKMIYRVAT 427
            :.....:|     :|....|.:.|| ::.|             |.:......|      :..|||
  Fly   389 TWEEGKDF-----EFQRPPQAVNFN-DIDD-------------GSLVNKTFIV------LISVAT 428

  Fly   428 RIGPPYFSYNETARELNLTGNALYQGYAVDLIDAIARHVGFEYVFVPVADQQYGKLDKETKQWNG 492
            :   ||.|..|:..  .|.||..:|||.||||..:|..:||.:.|.. ....||..:|.|...:|
  Fly   429 K---PYASLVESID--TLIGNNQFQGYGVDLIKELADKLGFNFTFRD-GGNDYGSFNKTTNSTSG 487

  Fly   493 IIGEIINNDAHMGICDLTITQARKTAVDFTVPFMQLGVSILAYKSPHVEKTLDAYLAPFGGEVWI 557
            ::.||:...|.:.|.|||||..|:..:||::|||.||::||..|.......|.:::.||..|||:
  Fly   488 MLKEIVEGRADLAITDLTITSEREEVIDFSIPFMNLGIAILYVKPQKAPPALFSFMDPFSSEVWL 552

  Fly   558 WILISVFVMTFLKTIVARISKMDWENPHPCNRDPEVLENQWRIHNTGWLTVASIMTAGCDILPRS 622
            ::.|:...::....|:.|:|.::|:||:||..:||.||||:.|:|:.|.|..:::..|.:|.|::
  Fly   553 YLGIAYLGVSLCFFIIGRLSPIEWDNPYPCIEEPEELENQFTINNSLWFTTGALLQQGSEIAPKA 617

  Fly   623 PQVRMFEATWWIFAIIIANSYTANLAAFLTSSKMEGSIANLKDLSAQK-KVKFGTIYGGSTYNLL 686
            ...|...|.||.|.:|:.:|||||||||||.......|.::|||:..| .|::|....|||.|..
  Fly   618 LSTRTISAIWWFFTLIMVSSYTANLAAFLTIENPTSPINSVKDLADNKDDVQYGAKRTGSTRNFF 682

  Fly   687 ADSNETVYRLAFNLMNNDDPSAYTKDNLEGVDRVRKNRGDYMFLMETTTLEYHREQNCDLRSVGE 751
            :.|.|.:| :..|...|..|....::|.:|||:| |:...|.||||:|::|::..:.|:|..||:
  Fly   683 STSEEPIY-IKMNEYLNAHPEMLMENNQQGVDKV-KSGTKYAFLMESTSIEFNTVRECNLTKVGD 745

  Fly   752 KFGEKHYAIAVPFGAEYRSNLSVAILKLSERGELYDLKQKWWKNPNAS-CFEEPDPDATPDMTFE 815
            ...||.|.||:.....||...:.|:|:|.|:|.|..||.|||....|. |..:.|.|...::..:
  Fly   746 PLDEKGYGIAMVKNWPYRDKFNKALLELQEQGVLARLKNKWWNEVGAGVCSAKSDDDGPSELGVD 810

  Fly   816 ELRGIFYTLYAGILIAFLIGITEFLVYVQQVALEERLTFKDAFKKEIRFVLCVWNNRKPIVAGTP 880
            .|.||:..|..|.:|:.:|.|..:..:|.:.|....:.|.||..:|.|.|:....|.:|:.:...
  Fly   811 NLSGIYVVLVIGSIISIIISILCWCYFVYKKAKNYEVPFCDALAEEFRIVIRFSENERPLKSAQS 875

  Fly   881 ISSVRTTPRRSLD 893
            |.|......:|::
  Fly   876 IYSRSRNSSQSIE 888

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
GluRIIC	NP_608557.4	Periplasmic_Binding_Protein_type1	26..409	CDD:471960	85/429 (20%)
		PBP2_iGluR_Kainate	423..794	CDD:270432	142/371 (38%)
		Lig_chan	554..827	CDD:459656	102/274 (37%)
GluRIID	NP_651982.1	PBP1_iGluR_Kainate	35..400	CDD:380605	80/399 (20%)
		PBP2_iGluR_Kainate	417..788	CDD:270432	143/384 (37%)
		Lig_chan	547..819	CDD:459656	101/273 (37%)